Results 11 to 20 of about 71,650 (224)
A dhfr-ts- Leishmania major Knockout Mutant Cross-protects against Leishmania amazonensis [PDF]
Memorias do Instituto Oswaldo Cruz, 1999 E10-5A3 is a dhfr-ts- Leishmania major double knockout auxotrophic shown previously to induce substantial protection against virulent L. major infection in both genetically susceptible and resistant mice.
PST Veras +8 more
doaj +4 more sources
Increased transmission potential of Leishmania major/Leishmania infantum hybrids [PDF]
International Journal for Parasitology, 2007 Development of Leishmania infantum/Leishmania major hybrids was studied in two sand fly species. In Phlebotomus papatasi, which supported development of L. major but not L. infantum, the hybrids produced heavy late-stage infections with high numbers of metacyclic promastigotes.
Petr, Volf +5 more
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Cloning of Leishmania Major P4 Gene [PDF]
Cell Journal, 2008 Objective: Leishmania major P4 gene is normally expressed during amastigote form ofthe parasite and can be good candidate for producing an effective vaccine.
Minoo Shaddel +4 more
doaj +1 more source
Plasmenylethanolamine synthesis in Leishmania major [PDF]
Molecular Microbiology, 2016 SummaryEthanolamine glycerophospholipids are ubiquitous cell membrane components. Trypanosomatid parasites of the genus Leishmania synthesize the majority of their ethanolamine glycerophospholipids as 1‐O‐alk‐1′‐enyl‐2‐acyl‐sn‐glycero‐3‐phosphoethanolamine or plasmenylethanolamine (PME) through the Kennedy pathway.
Pawlowic, Mattie C. +4 more
openaire +3 more sources
Structure ofLeishmania majorcysteine synthase [PDF]
Acta Crystallographica Section F Structural Biology and Crystallization Communications, 2012 Cysteine biosynthesis is a potential target for drug development against parasiticLeishmaniaspecies; these protozoa are responsible for a range of serious diseases. To improve understanding of this aspect ofLeishmaniabiology, a crystallographic and biochemical study ofL.
Fyfe, Paul K +5 more
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Comparative Gene Expression Profiles of Leishmania major and Leishmania infantum Promastigotesa
Turkiye parazitolojii dergisi, 2021 This study aimed to determine the differences between the gene expression profiles of Leismania major and Leishmania infantum promastigotes through comparative analysis of gene expressions.Cell culture of L. major (MHOM/IL/80) and L. infantum (MHOM/MA/67/ITMAP/263) cell lines was performed.
Özlem Ulusan Bağcı +2 more
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Leishmania major: Parasite Interactions Suggesting Sexuality [PDF]
Memorias do Instituto Oswaldo Cruz, 1997 In five experiments, Leishmania (Leishmania) major (MRHO/SU/59/P-strain) grew poorly when seeded in FYTS medium supplemented with 15% fetal calf serum, but presented several peculiar pairs of promastigotes diametrically opposed and attached at their ...
Sousa Maria Auxiliadora de +2 more
doaj +3 more sources
In Vitro Screening Test Using Leishmania Promastigotes Stably Expressing mCherry Protein [PDF]
, 2014 Transgenic Leishmania major and Leishmania donovani axenic promastigotes constitutively expressing mCherry were used for in vitro antileishmanial drug screening. This method requires minimal sample manipulation and can be easily adapted to automatic drug
Miguel A. Morales, Vacchina, Paola
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Mixed Mucosal Leishmaniasis Infection Caused by Leishmania tropica and Leishmania major [PDF]
Journal of Clinical Microbiology, 2012 ABSTRACT Mixed infections with different Leishmania species could explain differences in the clinical courses of these infections. On identification of Leishmania parasites from Iranian patients with mucosal leishmaniasis (ML), a patient with both oral and nasal lesions was found to
Sadegh, Shirian +3 more
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Treatment Outcome of the Drug-resistant Zoonotic Cutaneous Leishmaniasis by Glucantime
Advanced Biomedical Research, 2017 Background: Resistance of Leishmania species to antimonial drugs has increased. Hence, in the present study Leishmania major isolates were collected from patients with resistance phenotype and the presence/absence of resistance to Glucantime was ...
Simindokht Soleimanifard +4 more
doaj +1 more source