Results 11 to 20 of about 36,816 (193)

The SNARE protein family of Leishmania major [PDF]

BMC Genomics, 2006
Abstract Background Leishmania major is a protozoan parasite with a highly polarised cell shape that depends upon endocytosis and exocytosis from a single area of the plasma membrane, the flagellar pocket.
Besteiro, S., Coombs, G.H., Mottram, J.C.   +2 more
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Increased transmission potential of Leishmania major/Leishmania infantum hybrids [PDF]

International Journal for Parasitology, 2007
Development of Leishmania infantum/Leishmania major hybrids was studied in two sand fly species. In Phlebotomus papatasi, which supported development of L. major but not L. infantum, the hybrids produced heavy late-stage infections with high numbers of metacyclic promastigotes.
Petr, Volf, Ivana, Benkova, Jitka, Myskova, Jovana, Sadlova, Lenea, Campino, Christophe, Ravel   +5 more
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Plasmenylethanolamine synthesis in Leishmania major [PDF]

Molecular Microbiology, 2016
SummaryEthanolamine glycerophospholipids are ubiquitous cell membrane components. Trypanosomatid parasites of the genus Leishmania synthesize the majority of their ethanolamine glycerophospholipids as 1‐O‐alk‐1′‐enyl‐2‐acyl‐sn‐glycero‐3‐phosphoethanolamine or plasmenylethanolamine (PME) through the Kennedy pathway.
Pawlowic, Mattie C., Hsu, Fong Fu, Moitra, Samrat, Biyani, Neha, Zhang, Kai   +4 more
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The LPG1 gene family of Leishmania major [PDF]

Molecular and Biochemical Parasitology, 2004
In Leishmania major, the core of the abundant surface lipophosphoglycan (LPG) is structurally related to that of the smaller glycosylinositolphospholipids (GIPLs) in containing galactosylfuranose (Gal(f)) residues in a Gal(f) (beta1, 3)Man motif. However, deletion of the putative Gal(f)-transferase (Gal(f)T) LPG1 affected Gal(f) incorporation in LPG ...
Kai, Zhang, Tamara, Barron, Salvatore J, Turco, Stephen M, Beverley   +3 more
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The Genome of the Kinetoplastid Parasite, Leishmania major [PDF]

Science, 2005
Leishmania species cause a spectrum of human diseases in tropical and subtropical regions of the world. We have sequenced the 36 chromosomes of the 32.8-megabase haploid genome of Leishmania major (Friedlin strain) and predict 911 RNA genes, 39 pseudogenes, and 8272 ...
Ivens, A.C., Peacock, C.S., Worthey, E.A., Murphy, L., Aggarwal, G., Berriman, M., Sisk, E., Rajandream, M.A., Adlem, E., Aert, Rita, Anupama, A., Myler, P.J., Apostolou, Z., Attipoe, P., Bason, N., Bauser, C., Beck, A., Beverley, S.M., Bianchettin, G., Borzym, K., Bothe, G., Bruschi, C.V., Collins, M., Cadag, E., Ciarloni, L., Clayton, C., Coulson, R.MR., Cronin, A., Cruz, A.K., Davies, R.M., De Gaudenzi, J., Dobson, D.E., Duesterhoeft, A., Fazelina, G., Fosker, N., Frasch, A.C., Fraser, A., Fuchs, M., Gabel, C., Goble, A., Goffeau, A., Harris, D., Hertz-Fowler, C., Hilbert, H., Horn, D., Huang, Y.T., Klages, S., Knights, A., Kube, M., Larke, N., Litvin, L., Lord, A., Louie, T., Marra, M., Masuy, D., Matthews, K., Michaeli, S., Mottram, J.C., Muller-Auer, S., Munden, H., Nelson, S., Norbertczak, H., Oliver, K., O'Neil, S., Pentony, M., Pohl, T.M., Price, C., Purnelle, B., Quail, M.A., Rabbinowitsch, E., Reinhardt, R., Rieger, M., Rinta, J., Robben, Johan, Robertson, L., Ruiz, J.C., Rutter, S., Saunders, D., Schafer, M., Schein, J., Schwartz, D.C., Seeger, K., Seyler, A., Sharp, S., Shin, H., Sivam, D., Squares, R., Squares, S., Tosato, V., Vogt, C., Volckaert, Guido, Wambutt, R., Warren, T., Wedler, H., Woodward, J., Zhou, S.G., Zimmermann, W., Smith, D.F., Blackwell, J.M., Stuart, K.D., Barrell, B.   +100 more
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Structure ofLeishmania majorcysteine synthase [PDF]

Acta Crystallographica Section F Structural Biology and Crystallization Communications, 2012
Cysteine biosynthesis is a potential target for drug development against parasiticLeishmaniaspecies; these protozoa are responsible for a range of serious diseases. To improve understanding of this aspect ofLeishmaniabiology, a crystallographic and biochemical study ofL.
Fyfe, Paul K, Westrop, Gareth D, Ramos, Tania, Müller, Sylke, Coombs, Graham H, Hunter, William N   +5 more
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Updates on Geographical Dispersion of Leishmania Parasites Causing Cutaneous Affections in Algeria

Pathogens, 2021
Leishmaniases are neglected tropical diseases of public health concern in Algeria. To update the geographical distribution of Leishmania spp. causing cutaneous affection, we examined a set of Giemsa-stained smears prepared from skin lesions of the ...
Arezki Izri, Amina Bendjaballah-Laliam, Denis Sereno, Mohammad Akhoundi   +3 more
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Cyclic nucleotide specific phosphodiesterases of Leishmania major [PDF]

BMC Microbiology, 2006
Abstract Background Leishmania represent a complex of important human pathogens that belong to the systematic order of the kinetoplastida. They are transmitted between their human and mammalian hosts by different bloodsucking sandfly vectors.
Johner A, Kunz S, Linder M, Shakur Y, Seebeck T   +4 more
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Leishmania vaccines entered in clinical trials: A review of literature

International Journal of Preventive Medicine, 2019
Leishmaniasis is considered as a zoonotic infection and neglected tropical disease. Leishmania treatment is not totally successful and imposes high expenditures, especially in developing countries. Since the natural infection leads to the robust immunity
Mohammad Moafi, Hossein Rezvan, Roya Sherkat, Roya Taleban   +3 more
doaj   +1 more source

Comorbidity of Leishmania major with cutaneous sarcoidosis

Indian Journal of Dermatology, 2014
leishmaniasis infection might manifest as sarcoidosis; on the other hand, some evidences propose an association between sarcoidosis and leishmaniasis. Most of the times, it is impossible to discriminate idiopathic sarcoidosis from leishmaniasis by conventional histopathologic exam.We performed a cross-sectional study to examine the association of ...
Hamideh Moravvej, Parvaneh Vesal, Ehsan Abolhasani, Shizar Nahidi, Fereidoun Mahboudi   +4 more
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