Results 71 to 80 of about 9,389 (214)

Toll-like receptors 2, 4, and 9 expressions over the entire clinical and immunopathological spectrum of American cutaneous leishmaniasis due to Leishmania(V.) braziliensis and Leishmania (L.) amazonensis. [PDF]

PLoS One, 2018
Leishmania (V.) braziliensis and Leishmania(L.) amazonensis are the most pathogenic agents of American Cutaneous Leishmaniasis in Brazil, causing a wide spectrum of clinical and immunopathological manifestations, including: localized cutaneous leishmaniasis (LCLDTH+/++), borderline disseminated cutaneous leishmaniasis (BDCLDTH±), anergic diffuse ...
Campos MB, Lima LVDR, Lima LVDR, de Lima ACS, Vasconcelos Dos Santos T, Ramos PKS, Gomes CMC, Silveira FT.   +7 more
europepmc   +5 more sources

Health Benefits and Therapeutic Potential of Quercetin

Journal of Food Biochemistry, Volume 2026, Issue 1, 2026.
Quercetin, a polyphenolic compound prevalent in many fruits, vegetables, and other dietary sources, has attracted considerable interest due to its extensive health benefits. This review examines its diverse biological properties, particularly its antioxidant and anti‐inflammatory effects. The study integrates recent scientific findings to elucidate the
Mahendra Aryal, Kim Wei Chan
wiley   +1 more source

Piplartine as an Innovative Natural Product With Dual Antiparasitic and Immunomodulatory Actions

Journal of Immunology Research, Volume 2026, Issue 1, 2026.
Neglected tropical diseases (NTDs) remain a major global health burden, disproportionately affecting low‐ and middle‐income regions and demanding innovative therapeutic strategies. This review summarizes current evidence on piplartine (piperlongumine), a naturally occurring amide from Piper species with broad antiparasitic and immunomodulatory ...
Lucas Fukui-Silva, Felipe C. R. de Souza, Camila S. Amorim, Josué de Moraes, Poorani Gurumallesh Prabu   +4 more
wiley   +1 more source

Geospatial analysis of tegumentary leishmaniasis in Rio de Janeiro state, Brazil from 2000 to 2015: Species typing and flow of travelers and migrants with leishmaniasis.

PLoS Neglected Tropical Diseases, 2019
BackgroundWe identified the species of Leishmania isolated from traveling and migrant patients attended in a reference center from 2000 to 2015, we performed the georeferencing of these species in Rio de Janeiro (RJ) state and we had knowledge about the ...
Luciana de Freitas Campos Miranda, Raquel da Silva Pacheco, Maria Inês Fernandes Pimentel, Mariza de Matos Salgueiro, Aline Fagundes da Silva, Cíntia Xavier de Mello, Juliana Helena da Silva Barros, Claudia Maria Valete-Rosalino, Maria de Fátima Madeira, Samanta Cristina das Chagas Xavier, Armando de Oliveira Schubach   +10 more
doaj   +1 more source

Severe Cutaneous Leishmaniasis in a Human Immunodeficiency Virus Patient Coinfected with Leishmania braziliensis and Its Endosymbiotic Virus. [PDF]

, 2016
Leishmania parasites cause a broad range of disease, with cutaneous afflictions being, by far, the most prevalent. Variations in disease severity and symptomatic spectrum are mostly associated to parasite species.
Adaui, Alexia Cusini, Alvar, Alvar, Amato, Amato, Bourreau, Carvalho, Carvalho, Catherine Ronet, Chantal Desponds, Costa, Couppie, de Souza e Souza, el Tai, Goto, Guerra, Haroun Zangger, Hartley, Ives, Laurent Parmentier, Lindoso, Machado, Machado, Mary-Anne Hartley, Nicolas Fasel, Norbert Müller, Patrick Dubach, Patrik Castiglioni, Reithinger, Salinas, Silveira, Stephen M. Beverley, Tarr, Turetz, Widmer, Zangger, Zangger   +37 more
core   +3 more sources

Oxidative Stress Modulation and Antileishmanial Activity of Salvinia auriculata

Chemistry &Biodiversity, Volume 22, Issue 12, December 2025.
Ethanolic extract of Salvinia auriculata showed significant antioxidant and antileishmanial activities. Salviniside II, the major metabolite, was isolated, structurally characterized, and evaluated, but exhibited weaker antiparasitic effects when compared to the whole extract.
Augusto César Rodrigues, Emilha Uzum Papaya, Fernanda da Silva, Carla Cardozo Pinto de Arruda, Edson Lucas dos Santos, Kely de Picoli Souza, Carlos Alexandre Carollo   +6 more
wiley   +1 more source

Cutaneous leishmaniasis caused by members of Leishmania braziliensis complex in Nayarit, State of Mexico

Memorias do Instituto Oswaldo Cruz, 2001
An epidemiological study was carried out in the northern Mexican state, Nayarit. Fourteen patients with possible cutaneous leishmaniasis skin lesions gave positive Montenegro skin tests.
Gustavo Sanchez-Tejeda, Noris Rodríguez, Carlos I Parra, Omar Hernandez-Montes, Douglas C Barker, Amalia Monroy-Ostria   +5 more
doaj   +1 more source

De-novo design of complementary (antisense) peptide mini-receptor inhibitor of interleukin 18 (IL-18).

, 2004
Complementary (antisense) peptide mini-receptor inhibitors are complementary peptides designed to be receptor-surrogates that act by binding to selected surface features of biologically important proteins thereby inhibiting protein-cognate receptor ...
Bhakoo, Ashish, Heal, Jonathan R, Keller, Michael, Miller, Andrew D, Raynes, John G   +4 more
core   +1 more source

Mapping the Burden of Tegumentary Leishmaniasis in South America: A Systematic Review and Meta‐Analysis

Tropical Medicine &International Health, Volume 30, Issue 12, Page 1261-1268, December 2025.
ABSTRACT Introduction In recent years, the global burden of tegumentary leishmaniasis (TL) has significantly increased in the Americas. Objective To estimate the prevalence of TL in South America based on publications from the past 13 years. Methods Three databases were searched, and articles were selected based on inclusion criteria and methodological
Sérgio Caldas, Job Alves de Souza Filho, Janete Soares Coelho Santos, Felipe Campos de Melo Iani, Cristiane Faria de Oliveira Scarponi   +4 more
wiley   +1 more source

Capacidad infectiva de promastigotes en fase estacionaria de leishmania (viannia) braziliensis y leishmania (viannia) peruviana, en línea celular dh82

Revista Peruana de Medicina Experimental y Salud Pública
Objetivos. Determinar la capacidad infectiva de los promastigotes de Leishmania (V.) peruviana y Leishmania (V.) braziliensis en la línea celular macrófago-monocítica de Canis familiaris DH82. Materiales y métodos.
Karen Daphne Calvay-Sánchez, Nyshon Máximo Rojas-Palomino, Aidé Clorinda Sandoval-Juarez, Alberto Cisneros-Tarmeño, Cristian Obregón-Cahuaya, Gloria Sonia Minaya-Gómez   +5 more
doaj   +2 more sources