American Tegumentary Leishmaniasis: Is Antimonial Treatment Outcome Related to Parasite Drug Susceptibility? [PDF]
BackgroundAntimonials are the first drug of choice for the treatment of American tegumentary leishmaniasis (ATL); however, their efficacy is not predictable, and this may be linked to parasite drug resistance.
Adui, Vanessa +11 more
core
Comparison of gene expression patterns among Leishmania braziliensis clinical isolates showing a different in vitro susceptibility to pentavalent antimony [PDF]
Introduction. Evaluation of Leishmania drug susceptibility depends on in vitro SbV susceptibility assays, which are labour-intensive and may give a biased view of the true parasite resistance. Molecular markers are urgently needed to improve and simplify
ADAUI, V. +11 more
core
[Leishmania (Viannia) braziliensis in naturally infected dogs].
Eight dogs from Maricá Municipality (RJ), with suggestive lesion of American tegumentary leishmaniasis were studied by parasitological and serological methods. Leishmania spp was found in six dogs by in vitro cultivation. Specific antibodies were detected in six dogs by ELISA and in two by indirect immunofluorescence. Five canine isolates were found to
Maria de Fátima, Madeira Md +6 more
openaire +1 more source
Introduction: Multilocus enzyme electrophoresis (MLEE) is the reference standard for the characterization of Leishmania species. The test is restricted to specialized laboratories due to its technical complexity, cost, and time required to obtain results.
Clemencia Ovalle-Bracho +3 more
doaj +1 more source
Participation of heparin binding proteins from the surface of Leishmania (Viannia) braziliensis promastigotes in the adhesion of parasites to Lutzomyia longipalpis cells (Lulo) in vitro [PDF]
Background: Leishmania (V.) braziliensis is a causative agent of cutaneous leishmaniasis in Brazil. During the parasite life cycle, the promastigotes adhere to the gut of sandflies, to avoid being eliminated with the dejection.
Alves, Carlos Roberto +12 more
core +3 more sources
Vaccination of dogs against Leishmania (Viannia) braziliensis [PDF]
Mayrink, Wilson +9 more
openaire +5 more sources
Objectives. To determine the infectivity of promastigotes of Leishmania (V.) peruviana and Leishmania (V.) braziliensis in monocyte-macrophage cell line DH82 of Canis familiaris. Materials and methods. Was conducted a experimental study during the months of january to december 2013. Were used strains of Leishmania were used (V.) braziliensis MHOM / PE /
Calvay-Sánchez, Karen Daphne +5 more
openaire +4 more sources
Leishmaniasis: A review of the disease and the debate over the origin and dispersal of the causaitive parasite Leishmania [PDF]
The vector borne disease Leishmaniasis, caused by the Leishmania parasite, is estimated to affect the lives of 12 million people. Manifesting itself into three different clinical forms that center on disfiguring sores and enlargement of several organs ...
MacMorris-Adix, Molly
core +1 more source
Risk factors for cutaneous leishmaniasis transmission in children aged 0 to 5 years in an endemic area of Leishmania (Viannia) braziliensis [PDF]
With the purpose of identifying risk factors for cutaneous leishmaniasis transmission in children from 0 to 5 years, a matched case-control study was carried out in Corte de Pedra, Bahia, Brazil, an endemic area of Leishmania (Viannia) braziliensis ...
Ampuero Vela, Julia Sonia +2 more
core +2 more sources
Changes in Macrophage Gene Expression Associated with Leishmania (Viannia) braziliensis Infection
Different Leishmania species cause distinct clinical manifestations of the infectious disease leishmaniasis. It is fundamentally important to understand the mechanisms governing the interaction between Leishmania and its host cell. Little is known about this interaction between Leishmania (Viannia) braziliensis and human macrophages.
Clemencia Ovalle-Bracho +4 more
openaire +4 more sources

