Results 191 to 200 of about 11,204 (214)

In vitro promastigote fitness of putative Leishmania (Viannia) braziliensis/Leishmania (Viannia) peruviana hybrids

Acta Tropica, 1999
In order to initiate studies on the phenotypic properties of hybrids vs. their putative parents, the in vitro growth behaviour of promastigotes was compared for 15 stocks characterised as Leishmania (Viannia) braziliensis, Leishmania (Viannia) peruviana and putative hybrids (isolated from the Eastern Andean valley of Huanuco, Peru).
Torrico, M. C., De Doncker, S., Arevalo, J., Le Ray, D., Dujardin, J. C.   +4 more
openaire   +2 more sources

Cysteine proteinases from promastigotes of Leishmania (Viannia) braziliensis

Parasitology Research, 2009
Leishmania (Viannia) braziliensis is the major causative agent of American tegumentary leishmaniasis, a disease that has a wide geographical distribution and is a severe public health problem. The cysteine proteinase B (CPB) from Leishmania spp. represents an important virulence factor. In this study, we characterized and localized cysteine proteinases
Karina M, Rebello, Luzia M C, Côrtes, Bernardo A S, Pereira, Bernardo M O, Pascarelli, Suzana, Côrte-Real, Léa C, Finkelstein, Rosa T, Pinho, Claudia M, d'Avila-Levy, Carlos R, Alves   +8 more
openaire   +2 more sources

Heparin binding proteins from Leishmania (Viannia) braziliensis promastigotes

Veterinary Parasitology, 2007
We have examined the heparin binding proteins from Leishmania (Viannia) braziliensis promastigotes (HBP-Lb) by chromatography assays. The proposed strategy to isolate an enriched fraction of the HBP-Lb consisted of an association of the Triton X-114 method with affinity chromatography in heparin-Sepharose 4B column.
Azevedo-Pereira, R. L., Pereira, M. C. S., Oliveria Junior, F. O. R., Brazil, R. P., Cortes, L. M. C., Madeira, M. F., Santos, A. L. S., Toma, L., Alves, C. R.   +8 more
openaire   +3 more sources

Immunological selection forLeishmania(Viannia)braziliensisantigens

Annals of Tropical Medicine & Parasitology, 2001
Comparative ELISA and selective immunoblotting procedures were used in attempts to identify differential serological indicators of infection with the Leishmania (Viannia) braziliensis complex, infection with the L. braziliensis species, and therapeutic cure of localized or mucocutaneous leishmaniasis (LCL or MCL).
C A, Cuba Cuba, W, Ogunkolade, M K, Howard, M A, Miles   +3 more
openaire   +2 more sources

In vitro selection of ketoconazole-pentamidine-resistant Leishmania (Viannia) braziliensis strains

Experimental Parasitology, 2022
The use of ketoconazole (KTZ) plus pentamidine (PMD) could be an interesting treatment option for New World cutaneous leishmaniasis. The aim of this work was to generate KTZ- and PMD-resistant strains and to determine some characteristics of the selection process and the resulting parasites.
Mary Elízabeth Salazar-Villamizar, Patricia Escobar   +1 more
openaire   +2 more sources

Macrophage Polarisation During Leishmania (Viannia) braziliensis Infection in Mice

Parasite immunology (Print)
Leishmania (Viannia) braziliensis causes cutaneous and mucocutaneous leishmaniasis. Macrophages are host cells for parasite replication and act as effector cells against the parasite.
Marina Flóro e Silva, G. A. Roque, Lilian de Oliveira Coser, G. P. Jorge, Alexandre Leite Rodrigues de Oliveira, Francisca Janaína Soares Rocha, Selma Giorgio   +6 more
semanticscholar   +1 more source

Clinical complexity of Leishmania (Viannia) braziliensis infections amongst travelers

European Journal of Dermatology, 2013
The protozoan parasite Leishmania (Viannia) braziliensis is one of the main causes of cutaneous and mucocutaneous leishmaniasis in South America. Here, we describe three cases of L. (V.) braziliensis infection which were acquired during travelling in Bolivia, Peru or Paraguay and illustrate the phenotypic heterogeneity and therapeutic complexity of the
Saskia, Eichner, Sybille, Thoma-Uszynski, Ilka, Herrgott, Heidi, Sebald, Andrea, Debus, Athanasios, Tsianakas, Jan, Ehrchen, Gundel, Harms, Miklos, Simon, Cord, Sunderkötter, Christian, Bogdan   +10 more
openaire   +2 more sources

Leishmanicidal activity of synthetic chalcones in Leishmania (Viannia) braziliensis

Experimental Parasitology, 2014
The treatment of American cutaneous leishmaniasis (ACL) is based on a small group of compounds that were developed decades ago, all of which are highly toxic and have a high rate of treatment failure. The chalcones show leishmanicidal activity, yet few studies have evaluated this activity against Leishmania (Viannia) braziliensis, one of the most ...
Tatiane F P, de Mello, Heriberto R, Bitencourt, Raissa B, Pedroso, Sandra M A, Aristides, Maria V C, Lonardoni, Thais G V, Silveira   +5 more
openaire   +2 more sources

Antileishmanial Activity of Azitahromycin Against Leishmania (Leishmania) amazonensis, Leishmania (Viannia) braziliensis, and Leishmania (Leishmania) chagasi

The American Journal of Tropical Medicine and Hygiene, 2008
Azithromycin, an azalide antibiotic, is highly concentrated within different phagocytic cells, especially macrophages. The potential antileishmanial activity of azithromycin against three species of Leishmania from the New World was assessed using in vitro models.
Fernanda, de Oliveira-Silva, Eliane, de Morais-Teixeira, Ana, Rabello   +2 more
openaire   +2 more sources

Lack of relationship on in vitro susceptibility of Leishmania (Viannia) braziliensis promastigotes and Leishmania RNA virus 1 to the trivalent antimonial

Revista Eletrônica Acervo Saúde
Objective: To evaluate the relationship between the presence/viral load of Leishmania RNA virus 1 (LRV1) and the in vitro susceptibility of Leishmania (Viannia) braziliensis promastigotes to trivalent antimony (SbIII).
Enmanuella Helga Ratier Terceiro de Medeiros, Cristiane Batista Mattos, S. N. Fialho, Ana Karoline da Cruz Silva, Claudino Limeira Souza, C. Teles, L. M. Cantanhêde, Moreno Magalhães de Souza Rodrigues, Ricardo de Godoi Matos Ferreira, Gabriel Eduardo Melim Ferreira   +9 more
semanticscholar   +1 more source