Results 91 to 100 of about 47,700 (222)

Utility of Lymph Node Aspiration in the Diagnosis of Visceral Leishmaniasis in Sudan. [PDF]

open access: yes, 2007
We evaluated lymph node aspiration (LNA) as a simple diagnostic procedure for visceral leishmaniasis (VL). Lymph node aspiration was compared with the direct agglutination test (DAT) using a diagnostic titer > or = 1:6,400 in 7,880 suspected VL patients ...
Babiker, Z O E   +4 more
core   +1 more source

The epidemiology of canine leishmaniasis: transmission rates estimated from a cohort study in Amazonian Brazil [PDF]

open access: yes, 1997
We estimate the incidence rate, serological conversion rate and basic case reproduction number (R0) of Leishmania infantum from a cohort study of 126 domestic dogs exposed to natural infection rates over 2 years on Marajó Island, Pará State, Brazil.
Courtenay, O.   +3 more
core   +1 more source

Exploring Novel Nitrofuryl‐1,3,4‐Thiadiazole‐Based Derivatives: Design, Synthesis, and Evaluation of In Vitro Leishmanicidal and Trypanocidal Activity

open access: yesArchiv der Pharmazie, Volume 359, Issue 3, March 2026.
In a series of substituted 1‐[5‐(5‐nitrofuran‐2‐yl)‐1,3,4‐thiadiazol‐2‐yl]piperidine‐4‐carboxamides evaluated for in vitro antileishmanial and antitrypanosomal activity, compound 18 emerged as the most promising derivative, showing submicromolar anti‐parasitic effects targeting diverse Leishmania and Trypanosoma species and acceptable selectivity ...
Alireza Mousavi   +17 more
wiley   +1 more source

Declining Visceral Leishmaniasis in Malta [PDF]

open access: yes, 2008
Aims: To study visceral leishmaniasis (VL) trends in Malta. Methods: Analysis of epidemiological and clinical trends, a veterinary questionnaire and questioning a canine laboratory testing facility.
Grech, Victor E., Vella, Cecil
core  

Synthesis and Antileishmanial Activity of 1,2,4,5-Tetraoxanes against Leishmania donovani [PDF]

open access: yes, 2020
A chemically diverse range of novel tetraoxanes was synthesized and evaluated in vitro against intramacrophage amastigote forms of Leishmania donovani. All 15 tested tetraoxanes displayed activity, with IC50 values ranging from 2 to 45 µm.
Amado, Patrícia   +5 more
core   +1 more source

Elimination of visceral leishmaniasis in Ethiopia: cross-sector collaboration and cost sharing to promote sustainability

open access: yesInternational Journal of Infectious Diseases
Objectives: Sustainable elimination of visceral leishmaniasis as a public health problem requires the contribution of various stakeholders led by the governments.
Duncan Ochol   +4 more
doaj   +1 more source

Leishmania donovani's protein tyrosine phosphatases interact with DUF21 and respond to environmental magnesium

open access: yesThe FEBS Journal, Volume 293, Issue 6, Page 1754-1770, March 2026.
The Leishmania phosphatase PTP1, and possibly the genetically similar PTP2, interacts with the Leishmania transmembrane protein DUF21. When both ptp1 and ptp2 are knocked out of Leishmania (LdΔPTP1/2), the parasite can no longer survive without magnesium in vitro and has reduced viability in the host macrophage. Conversely, in duf21 knockout (LdΔDUF21),
Kayla Paulini   +6 more
wiley   +1 more source

Leishmaniasis in rheumatoid arthritis

open access: yesReumatismo, 2011
Leishmaniasis represents a complex of diseases with an important clinical and epidemiological diversity. Visceral leishmaniasis is of higher priority than cutaneous leishmaniasis as it is a fatal disease in the absence of treatment. The clinical spectrum
M. Cutolo, M.E. Secchi, C. Pizzorni
doaj   +1 more source

Vulnerability to the transmission of human visceral leishmaniasis in a Brazilian urban area

open access: yesRevista de Saúde Pública
OBJECTIVE To analyze the determinants for the occurrence of human visceral leishmaniasis linked to the conditions of vulnerability. METHODS This is an ecological study, whose spatial analysis unit was the Territorial Analysis Unit in Araguaína, State ...
Celina Roma Sánchez de Toledo   +5 more
doaj   +1 more source

Is Visceral Leishmaniasis the same in HIV-coinfected adults?

open access: yesBrazilian Journal of Infectious Diseases, 2018
Introduction: Visceral Leishmaniasis is the most severe form of disease caused by the Leishmania donovani complex, with significant morbidity and mortality in developing countries.
Guilherme Alves de Lima Henn   +7 more
doaj   +1 more source

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