Results 81 to 90 of about 31,946 (227)

Amphotericin B deoxycholate for relapse visceral leishmaniasis in Bangladesh: a cross-sectional study

BMC Research Notes, 2018
Objective Based on studies in India (as there was no studies from outside India) amphotericin B deoxycholate has been considered as a backup drug for treatment of visceral leishmaniasis.
Md Golam Hasnain, Proggananda Nath, Shomik Maruf, Shah Golam Nabi, A. F. M. Akhtar Hossain, Be-Nazir Ahmed, Dinesh Mondal, Ariful Basher   +7 more
doaj   +1 more source

When macrophages have more than one thing to show

British Journal of Haematology, EarlyView.
Hachem Abou Moustafa, Maïlys Le Guyader, Pierre Loiseau, Yohann Le Govic, Thomas Boyer   +4 more
wiley   +1 more source

Clinical and Diagnostic Considerations in Laryngeal Leishmaniasis: A Systematic Review

OTO Open, Volume 10, Issue 3, July-September 2026.
Abstract Objective Laryngeal leishmaniasis is a rare, insidious manifestation of Leishmania infection with potential for life‐threatening complications. Awareness is critical for efficient and timely diagnosis. This systematic review of laryngeal leishmaniasis focuses on presentation, treatment, and the role of serological studies in the work up of ...
Joseph Celidonio, Nicholas Hamilton, Alexandra Filipkowski, Raj Malhotra, Samantha Shave, Myat E. Mon, Kenneth Yan, Rachel Kaye   +7 more
wiley   +1 more source

Development of an enzyme-linked immunosorbent assay to identify host-feeding preferences of Phlebotomus species (Diptera: Psychodidae) in endemic foci of visceral leishmaniasis in Nepal. [PDF]

, 2010
Anthroponotic visceral leishmaniasis, transmitted by Phlebotomus argentipes Annandale & Brunetti (Diptera: Psychodidae) sand flies, is regarded as a major problem of public health importance in the Indian subcontinent.
Roy, Lalita, Cameron, M., Matthew Rogers, Picado, Albert, Das, Murari, Cameron, Mary, Clive Davies, Davies, C., Ian Burniston, Mary Cameron, Boelaert, M., Lalita Roy, Boelaert, Marleen, Davies, Clive, Rogers, M., Burniston, I., Rijal, S., Marc Coosemans, Picado, A., Rogers, Matthew, Coosemans, Marc, Albert Picado, Marleen Boelaert, Coosemans, M., Burniston, Ian, Roy, L., Rijal, Suman, Murari Das, Das, M., Suman Rijal   +29 more
core   +1 more source

Recent autochthonous cases of leishmaniasis in residents of the Republic of Dagestan, Russian Federation

International Journal of Infectious Diseases, 2019
Eighty years after the last published record of human leishmaniasis from Dagestan, Russian Federation, we report two recent cases which were most probably acquired locally: one case of visceral leishmaniasis in a 2-year old child, and one cutaneous ...
Sergey Andreevich Nagorny, Larisa Alexandrovna Ermakova, Natalia Vladimirovna Golovchenko, Natalia Yurievna Pshenichnaya, Andrey Sergeevich Zhuravlev, Trentina Di Muccio, Luigi Gradoni   +6 more
doaj   +1 more source

Structural basis of ligand selectivity in FAD/NAD(P)H‐dependent dehydrogenases: insights from trypanothione reductase and type II NADH dehydrogenase

Protein Science, Volume 35, Issue 7, July 2026.
Abstract FAD/NAD(P)H‐dependent dehydrogenases form a structurally conserved family of redox enzymes that participate in essential metabolic processes across parasites and higher organisms. Among them, trypanothione reductase (TR) is a key component of the redox metabolism of Leishmania species and represents an attractive target for antileishmanial ...
Giulia Chiara Maria Perrone, Serena Spadone, Anna Lucia Francavilla, Sara Morselli, Sabino Todisco, Margherita Ortalli, Jairo Alfonso Mendoza‐Roldan, Valeria Scaglione, Maria Noemi Sgobba, Lorenzo Guerra, Federica Belluti, Stefania Varani, Domenico Otranto, Anna De Grassi, Mariateresa Volpicella, Ciro Leonardo Pierri   +15 more
wiley   +1 more source

Arsenic exposure and outcomes of antimonial treatment in visceral leishmaniasis patients in bihar, India:a retrospective cohort study [PDF]

, 2015
Background: In the late twentieth century, emergence of high rates of treatment failure with antimonial compounds (SSG) for visceral leishmaniasis (VL) caused a public health crisis in Bihar, India.
Joris Menten (95438), Prajapati Vijay K., Raab Andrea, Feldmann Joerg, Perry Meghan R., Meghan R Perry, Sundar Shyam, Chakraborti, Dipankar, Joerg Feldmann (343233), Alan H Fairlamb, Fairlamb, Alan H., Joerg Feldmann, Albert Picado (194712), Picado, Albert, Fairlamb, Alan H, Joris Menten, Boelaert Marleen, Meghan R. Perry (343229), Dipankar Chakraborti (253671), Sundar, Shyam, Menten, Joris, Fairlamb, Alan H.; id_orcid, Boelaert, Marleen, Andrea Raab, Prajapati, Vijay K., Raab, Andrea, Marleen Boelaert (56961), Dipankar Chakraborti, Shyam Sundar, Vijay K. Prajapati (697028), Picado Albert, Fairlamb Alan H., Feldmann, Joerg, Albert Picado, Marleen Boelaert, Picado de Puig, Albert, Chakraborti Dipankar, Shyam Sundar (58354), Alan H. Fairlamb (118600), Perry, Meghan R, Perry, Meghan R., Andrea Raab (249766), Prajapati, Vijay K, Vijay K Prajapati, Menten Joris   +44 more
core   +1 more source

Latent Class Log‐Linear Models for Estimating Diagnostic Test Accuracy Without a Gold Standard: A Simulation Study

Statistics in Medicine, Volume 45, Issue 15-17, July 2026.
ABSTRACT Background In the absence of a gold standard, latent class models can be used to estimate test accuracy from a study comparing results on multiple tests. Fixed‐effect and latent trait models are often used to account for conditional dependencies between tests, mitigating against biased accuracy estimates, but are difficult to implement. Latent
Yasin Okkaoglu, Nicky J. Welton, A. E. Ades, Hayley E. Jones   +3 more
wiley   +1 more source

Urine as a promising sample for Leishmania DNA extraction in the diagnosis of visceral leishmaniasis – a review

Brazilian Journal of Infectious Diseases, 2019
Visceral leishmaniasis is a serious and debilitating infection with high fatality rate in tropical and subtropical countries. As clinical symptoms of visceral leishmaniasis are not so specific, confirmatory diagnostic methods with high sensitivity and ...
Gilberto Silva Nunes Bezerra, Walter Lins Barbosa, Júnior, Elis Dionísio da Silva, Nilma Cintra Leal, Zulma Maria de Medeiros   +4 more
doaj   +1 more source

Elucidation of DNA Primase as a Drug Target in Leishmania donovani: Structure‐Guided Inhibitor Identification and Biochemical Validation

Chemical Biology &Drug Design, Volume 108, Issue 1, July 2026.
Structure‐guided and biochemical analyses indicate that DNA primase of Leishmania donovani represents a potential therapeutic target, as repurposed compounds, particularly Pritelivir, demonstrate marked inhibitory effects accompanied by reduced parasite proliferation, replication, and altered cellular morphology in in vitro and cell‐based studies ...
Deep Bhowmik, Anupama Sharma, Ravi Prakash Arya, Diwakar Kumar   +3 more
wiley   +1 more source