Results 61 to 70 of about 19,013 (180)

Knowledge mapping of risk mitigation measures against vector‐borne diseases

open access: yesEFSA Journal, Volume 24, Issue 5, May 2026.
Abstract A comprehensive synthesis of current evidence on surveillance, prevention and control measures for 25 selected vector‐borne diseases (VBDs) affecting animals in the EU is presented here. The assessment integrates evidence from systematic literature reviews, modelling studies, field investigations and expert judgement.
European Food Safety Authority (EFSA)   +8 more
wiley   +1 more source

Epidemiological aspects of human and canine visceral leishmaniasis in State of Alagoas, Northeast, Brazil

open access: yesBrazilian Journal of Biology, 2018
Zoonotic visceral leishmaniasis (ZVL), caused by protozoans of the genus Leishmania, it is a worldwide of great importance disease. In the northeast region of Brazil, the state of Alagoas has an endemic status for ZVL.
M. A. N. Rocha   +3 more
doaj   +1 more source

Targeting Kinetoplastid Parasites with ProTide Prodrugs: A Proof‐of‐Concept Study

open access: yesChemMedChem, Volume 21, Issue 7, 14 April 2026.
Neglected tropical diseases (NTDs) remain a major global health challenge, particularly in low‐ and middle‐income countries. Kinetoplastid parasites causing Chagas disease, leishmaniasis, and African trypanosomiasis rely on host purine salvage pathways, making nucleoside analogues attractive therapeutic candidates.
Silvester Lowe   +6 more
wiley   +1 more source

Amphotericin B deoxycholate for relapse visceral leishmaniasis in Bangladesh: a cross-sectional study

open access: yesBMC Research Notes, 2018
Objective Based on studies in India (as there was no studies from outside India) amphotericin B deoxycholate has been considered as a backup drug for treatment of visceral leishmaniasis.
Md Golam Hasnain   +7 more
doaj   +1 more source

Safety, tolerability and pharmacokinetics of DNDI‐6148, a novel agent for leishmaniasis: A randomized, controlled, single ascending dose study in healthy participants

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 4, Page 1087-1097, April 2026.
Aim The benzoxaborole derivative DNDI‐6148 is an antiparasitic agent with activity against multiple Leishmania protozoan species, including L. infantum and L. donovani, which cause visceral leishmaniasis. We investigated the safety, tolerability and pharmacokinetics of single oral doses of DNDI‐6148 in a randomized, parallel‐group, placebo‐controlled ...
Jean‐Yves Gillon   +12 more
wiley   +1 more source

Linking Targeted Pancreatic Cancer Genes With Metabolic Disorders: A Cross‐Species Translational Pathway

open access: yesCancer Medicine, Volume 15, Issue 4, April 2026.
ABSTRACT Introduction Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies because of its typically late diagnosis and limited treatment options, with surgical resection being the primary intervention. Emerging studies have consistently reported associations between PDAC and metabolic dysfunctions, including obesity ...
Dipanwita Nath   +5 more
wiley   +1 more source

Visceral leishmaniasis in lung transplantation

open access: yesTransplantation Proceedings, 2003
Infection by intracellular microorganisms with a special geographic distribution, such as Leishmania spp, has been reported in a limited number of patients undergoing solid-organ transplant (SOT). No cases of Leishmania spp infection in lung transplant patients were found in a review of the literature.
Morales, P.   +5 more
openaire   +3 more sources

Elimination of visceral leishmaniasis in Ethiopia: cross-sector collaboration and cost sharing to promote sustainability

open access: yesInternational Journal of Infectious Diseases
Objectives: Sustainable elimination of visceral leishmaniasis as a public health problem requires the contribution of various stakeholders led by the governments.
Duncan Ochol   +4 more
doaj   +1 more source

Vulnerability to the transmission of human visceral leishmaniasis in a Brazilian urban area

open access: yesRevista de Saúde Pública
OBJECTIVE To analyze the determinants for the occurrence of human visceral leishmaniasis linked to the conditions of vulnerability. METHODS This is an ecological study, whose spatial analysis unit was the Territorial Analysis Unit in Araguaína, State ...
Celina Roma Sánchez de Toledo   +5 more
doaj   +1 more source

Is Visceral Leishmaniasis the same in HIV-coinfected adults?

open access: yesBrazilian Journal of Infectious Diseases, 2018
Introduction: Visceral Leishmaniasis is the most severe form of disease caused by the Leishmania donovani complex, with significant morbidity and mortality in developing countries.
Guilherme Alves de Lima Henn   +7 more
doaj   +1 more source

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