Results 41 to 50 of about 180,299 (231)

Recent Development of Visceral Leishmaniasis Treatments: Successes, Pitfalls, and Perspectives

open access: yesClinical Microbiology Reviews, 2018
Research in visceral leishmaniasis in the last decade has been focused on how better to use the existing medicines as monotherapy or in combination. Systematic research by geographical regions has shown that a universal treatment is far from today's ...
F. Alves   +16 more
semanticscholar   +1 more source

Evaluación de una prueba de aglutinación directa como método alternativo para el diagnóstico de leishmaniasis visceral canina y humana en Venezuela

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2007
Introducción. La leishmaniasis visceral es la forma clínica más grave de la leishmaniasis. Ésta puede ser fatal si no se administra el tratamiento adecuado.
Guillermo Terán-Angel   +5 more
doaj   +1 more source

Cyclin-dependent kinase 12, a novel drug target for visceral leishmaniasis

open access: yesNature, 2018
Visceral leishmaniasis causes considerable mortality and morbidity in many parts of the world. There is an urgent need for the development of new, effective treatments for this disease.
S. Wyllie   +31 more
semanticscholar   +1 more source

Visceral leishmaniasis in Afghanistan [PDF]

open access: yesCanadian Medical Association Journal, 2006
Despite being the third most important vector-borne diseases worldwide in terms of burden of disease, the leishmaniases are one of the so-called “neglected diseases.” Since the massive humanitarian re-construction efforts began after the fall of the Taliban in 2002, Afghanistan is ...
Najibullah Mahboob   +8 more
openaire   +3 more sources

Current and promising novel drug candidates against visceral leishmaniasis

open access: yesPure and Applied Chemistry, 2019
Leishmaniasis is a group of zoonotic diseases caused by a trypanosomatid parasite mostly in impoverished populations of low-income countries. In their different forms, leishmaniasis is prevalent in more than 98 countries all over the world and ...
Rosa M. Reguera   +7 more
semanticscholar   +1 more source

Characterization of a municipality as free of canine visceral leishmaniasis in the context of One Health

open access: yesRevista Brasileira de Parasitologia Veterinária, 2021
Dogs are the main urban reservoir of Leishmania infantum, the causative agent of visceral leishmaniasis (VL), which is transmitted by sand flies. In the state of Paraná, the first detection of a positive dog for VL was in 2014, this year Paraná lost free
Silvia Cristina Osaki   +6 more
doaj   +1 more source

Mucosal relapse of visceral leishmaniasis in a child treated with anti-TNFα

open access: yesInternational Journal of Infectious Diseases, 2015
Visceral leishmaniasis is an enzootic parasitosis present across the Mediterranean Basin. Some consider it an opportunistic parasite. We report the case of a girl treated with anti-tumour necrosis factor alpha (anti-TNFα) for juvenile idiopathic ...
E. Jeziorski   +6 more
doaj   +1 more source

Non-Leishmania Parasite in Fatal Visceral Leishmaniasis–Like Disease, Brazil

open access: yesEmerging Infectious Diseases, 2019
Through whole-genome sequencing analysis, we identified non-Leishmania parasites isolated from a man with a fatal visceral leishmaniasis–like illness in Brazil. The parasites infected mice and reproduced the patient’s clinical manifestations.
S. Maruyama   +14 more
semanticscholar   +1 more source

Para-kala-azar dermal leishmaniasis in a patient in Brazil: a case report

open access: yesRevista da Sociedade Brasileira de Medicina Tropical
Visceral leishmaniasis is common in Brazil and is caused by Leishmania (Leishmania) infantum/chagasi. Post-kala-azar dermal leishmaniasis frequently follows visceral leishmaniasis caused by L.
José Angelo Lauletta Lindoso   +5 more
doaj   +1 more source

Acute liver failure due to visceral leishmaniasis in Barcelona: a case report

open access: yesBMC Infectious Diseases, 2019
Background Leishmaniasis is an emerging infectious disease. Due to human migration and tourism, visceral leishmaniasis may become more common in non-endemic areas. In the Mediterranean basin, visceral leishmaniasis typically occurs in rural regions. Case
Iratxe Martinez de Narvajas   +10 more
doaj   +1 more source

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