Results 51 to 60 of about 18,295 (182)

Epidemiology of visceral leishmaniasis [PDF]

Clinical Epidemiology, 2014
Leishmania species are the causative agents of leishmaniasis, a neglected tropical disease. These parasitic protozoans are usually transmitted between vertebrate hosts by the bite of blood sucking female phlebotomine sand flies. This review focuses on the two parasites causing most human visceral leishmaniasis (VL), which leads to substantial health ...
openaire   +4 more sources

Developing giant plasma membrane vesicles from Leishmania cells to investigate the role of membrane proteins in photodynamic inactivation

Photochemistry and Photobiology, EarlyView.
In this study, we developed giant plasma membrane vesicles (GPMVs) from Leishmania amazonensis promastigote membranes to investigate the role of protein‐embedded membranes in methylene blue (MB) photooxidation. Upon MB photoactivation in model lipid membranes (giant unilamellar vesicles, GUVs), a distinct photooxidation effect was observed, marked by ...
Maressa D. F. de Souza, Pietro Ciancaglini, Rosangela Itri, Martha S. Ribeiro   +3 more
wiley   +1 more source

A case report on para-kala-azar dermal leishmaniasis: an unresolved mystery

BMC Infectious Diseases, 2023
Background Post-kala-azar dermal leishmaniasis (PKDL) is a dermatosis that occurs 2–3 years after an apparently successful treatment of visceral leishmaniasis (VL).
Md. Mehedi Hasan, Sanghita Banik Proma, Md. Saddam Hossain, Md. Arifuzzaman, Naylla Islam, Md. Abu Bakar Siddique, Amiruzzaman   +6 more
doaj   +1 more source

Assessment of Leishmania exposure in blood donors from a non‐endemic urban area: A study in São Paulo

Vox Sanguinis, EarlyView.
Abstract Background and Objectives According to the World Health Organization, more than 1 billion people are at risk of leishmaniasis in over 89 countries. Environmental changes such as deforestation, urban expansion and climate change facilitate the spread of sand fly vectors and reservoirs, increasing disease transmission.
Ismael Severino de Lima, Suzete Cleusa Ferreira, Anna Shoko Nishiya, Norival Kesper Jr., Jerenice Esdras Ferreira, Claudia Maria de Castro Gomes, Juliana Derriga, Katia Cristina Dantas, Silvia Petrossi Gallo Polato, Nanci Alves Salles, Jose Angelo Lauletta Lindoso, Tila Fanciani, Cesar de Almeida‐Neto, Vanderson Rocha, Alfredo Mendrone Jr.   +14 more
wiley   +1 more source

Leishmaniasis–HIV coinfection: current challenges

HIV/AIDS: Research and Palliative Care, 2016
José Angelo Lauletta Lindoso,1,2 Mirella Alves Cunha,3 Igor Thiago Queiroz,4 Carlos Henrique Valente Moreira2 1Laboratory of Soroepidemiology (LIM HC-FMUSP), São Paulo University, São Paulo, 2Instituto de Infectologia Emilio ...
Lindoso JAL, Cunha MA, Queiroz IT, Moreira CHV   +3 more
doaj  

New Se‐Compounds With Antileishmanial, Antitumor, and Carbonic Anhydrase Inhibitory Properties

Archiv der Pharmazie, Volume 358, Issue 12, December 2025.
A small library of selenocompounds was evaluated for their antileishmanial, antitumoral, and human carbonic anhydrase (hCA) inhibitory properties. Two trifluoromethoxy‐substituted anilide derivatives (3 and 6) were the most effective ones against Leishmania major (L. major) and Leishmania infantum (L. infantum) promastigotes and also showed a promising
Cristina Morán‐Serradilla, Daniel Plano, Andrea Angelli, Arun K. Sharma, Carmen Sanmartin, Claudiu T. Supuran   +5 more
wiley   +1 more source

Epidemiological aspects of human and canine visceral leishmaniasis in State of Alagoas, Northeast, Brazil

Brazilian Journal of Biology, 2018
Zoonotic visceral leishmaniasis (ZVL), caused by protozoans of the genus Leishmania, it is a worldwide of great importance disease. In the northeast region of Brazil, the state of Alagoas has an endemic status for ZVL.
M. A. N. Rocha, T. J. Matos-Rocha, C. M. B. Ribeiro, S. R. O. Abreu   +3 more
doaj   +1 more source

Oxidative Stress Modulation and Antileishmanial Activity of Salvinia auriculata

Chemistry &Biodiversity, Volume 22, Issue 12, December 2025.
Ethanolic extract of Salvinia auriculata showed significant antioxidant and antileishmanial activities. Salviniside II, the major metabolite, was isolated, structurally characterized, and evaluated, but exhibited weaker antiparasitic effects when compared to the whole extract.
Augusto César Rodrigues, Emilha Uzum Papaya, Fernanda da Silva, Carla Cardozo Pinto de Arruda, Edson Lucas dos Santos, Kely de Picoli Souza, Carlos Alexandre Carollo   +6 more
wiley   +1 more source

Amphotericin B deoxycholate for relapse visceral leishmaniasis in Bangladesh: a cross-sectional study

BMC Research Notes, 2018
Objective Based on studies in India (as there was no studies from outside India) amphotericin B deoxycholate has been considered as a backup drug for treatment of visceral leishmaniasis.
Md Golam Hasnain, Proggananda Nath, Shomik Maruf, Shah Golam Nabi, A. F. M. Akhtar Hossain, Be-Nazir Ahmed, Dinesh Mondal, Ariful Basher   +7 more
doaj   +1 more source

Novel Nonsense Mutation in SMARCD2 Gene Results in Dysplasia of All Myeloid Cell Lines

eJHaem, Volume 6, Issue 6, December 2025.
ABSTRACT Introduction Specific granule deficiency type II (SGD2) is a rare heterogeneous congenital disease characterized by early‐onset life‐threatening infections. SGD2 is caused by autosomal recessive mutations in the SMARCD2 gene. Methods Prenatal screening in our patient revealed a novel homozygous nonsense mutation in SMARCD2 (c.208C>T, p.Gln70*).
Michelle A. E. Brouwer, Arie Arensman, H. Rob Taal, Emilie P. Buddingh, Su Ming Sun, Anthon Hulsmann, Lenneke Waals‐Prinzen   +6 more
wiley   +1 more source