Results 11 to 20 of about 109,328 (235)

Leishmaniasis [PDF]

open access: yesClinical Medicine, 2011
Leishmaniasis is an uncommon infectious disease in the UK with a variety of clinical presentations. Physicians should remember to consider this diagnosis in patients with an appropriate travel history (including the Mediterranean basin) and seek help with diagnostics from a specialised parasitology laboratory.
Elinor M, Moore, Diana N, Lockwood
openaire   +5 more sources

Brain Involvement in Leishmaniasis. [PDF]

open access: yesCell Biochem Funct
ABSTRACT Leishmaniasis is a neglected tropical disease caused by infection with the protozoan parasite Leishmania and it is a significant global health problem. The disease has a wide clinical spectrum, from tegumentary leishmaniasis (TL) that encompasses cutaneous (CL), mucosal (ML) and cutaneous‐diffuse (CDL) forms, to the potentially fatal systemic ...
Freitas CS   +2 more
europepmc   +2 more sources

Leishmaniasis

open access: yesIndian Journal of Critical Care Medicine, 2021
Leishmaniasis is one of the chronic debilitating vector-borne diseases caused by obligate intracellular protozoa. The global burden of disease although not increasing but potential risk of spread is there. At least 20 species of Leishmania are pathogenic to human beings. The transmission is from female sandfly through a blood meal.
Daga, Mradul K   +2 more
openaire   +3 more sources

Visceral Leishmaniasis in Somalia: Diagnosis and Management of a Classic Case in a Resource-Limited Endemic Setting. [PDF]

open access: yesClin Case Rep
ABSTRACT Visceral Leishmaniasis (VL), a severe systemic neglected tropical disease (NTD) caused by Leishmania donovani complex protozoa, poses a significant public health threat, particularly in East Africa, where it is fatal if untreated. Somalia is known to be endemic, but the true burden and programmatic challenges are poorly documented due to long ...
Hussein AN   +4 more
europepmc   +2 more sources

Infection Without Borders. [PDF]

open access: yesJ Paediatr Child Health
Journal of Paediatrics and Child Health, Volume 62, Issue 4, Page 650-651, April 2026.
Lu JT, Cheung K, Sebaratnam DF.
europepmc   +2 more sources

Translational Pharmacokinetic-Pharmacodynamic Modeling and Efficacious Human Dose Prediction of DNDI-6148 for the Treatment of Cutaneous Leishmaniasis. [PDF]

open access: yesClin Transl Sci
ABSTRACT Cutaneous leishmaniasis is a neglected tropical disease with only one oral treatment option. DNDI‐6148 is an orally bioavailable compound with potent antiparasitic activity in preclinical studies. Establishing skin target‐site pharmacokinetic/pharmacodynamic (PK/PD) relationships is essential to enable its clinical development.
Henninger RH   +7 more
europepmc   +2 more sources

Leishmaniasis [PDF]

open access: yesPostgraduate Medical Journal, 2006
Abstract Epidemiology, disease patterns, immunology, diagnosis, treatment and control measures of leishmaniasis are described. Various issues relating to leishmaniasis are highlighted: the relative lack of importance given to this disease is compared with other infections, climate change and its possible effect on extension of endemicity
Tonio V, Piscopo   +1 more
openaire   +4 more sources

Evaluation of a new live recombinant vaccine against cutaneous leishmaniasis in BALB/c mice

open access: yesParasites & Vectors, 2020
Background Leishmaniasis is a serious health problem in some parts of the world. In spite of the many known leishmaniasis control measures, the disease has continued to increase in endemic areas, and no effective vaccine has been discovered.
Samira Salari   +3 more
doaj   +1 more source

The epidemiology of canine leishmaniasis: transmission rates estimated from a cohort study in Amazonian Brazil [PDF]

open access: yes, 1997
We estimate the incidence rate, serological conversion rate and basic case reproduction number (R0) of Leishmania infantum from a cohort study of 126 domestic dogs exposed to natural infection rates over 2 years on Marajó Island, Pará State, Brazil.
Courtenay, O.   +3 more
core   +1 more source

Insights from mathematical modelling and quantitative analysis on the proposed WHO 2030 targets for visceral leishmaniasis on the Indian subcontinent [version 1; peer review: 2 approved]

open access: yesGates Open Research, 2019
Visceral leishmaniasis (VL) is a neglected tropical disease (NTD) caused by Leishmania protozoa that are transmitted by female sand flies. On the Indian subcontinent (ISC), VL is targeted by the World Health Organization (WHO) for elimination as a public
NTD Modelling Consortium Visceral Leishmaniasis Group
doaj   +1 more source

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