Results 51 to 60 of about 109,637 (271)

Leishmaniasis in Germany [PDF]

open access: yesEmerging Infectious Diseases, 2003
In 2000, a reference center was created to systematically record leishmaniases in Germany. We analyzed 58 cases of leishmaniases imported during a 2-year period. These findings will serve as a baseline for the sandfly vector's anticipated northward move because of global warming and as an advisory for immunocompromised persons traveling to ...
Gundel Harms   +2 more
openaire   +3 more sources

Drug resistance and treatment failure in leishmaniasis: A 21st century challenge

open access: yesPLoS Neglected Tropical Diseases, 2017
Reevaluation of treatment guidelines for Old and New World leishmaniasis is urgently needed on a global basis because treatment failure is an increasing problem.
A. Ponte-Sucre   +8 more
semanticscholar   +1 more source

The potential role and apoptotic profile of three medicinal plant extracts on Leishmania tropica by MTT assay, macrophage model and flow cytometry analysis

open access: yesParasite Epidemiology and Control, 2021
Introduction: Treatment of leishmaniasis with conventional synthetic drugs is a major global challenge. This study was designed to explore the leishmanicidal activity and apoptotic profile of three leaf extracts on Leishmania tropica stages. Methods: The
Mozhde Ilaghi   +8 more
doaj   +1 more source

Visceral leishmaniasis: a global overview

open access: yesJournal of Global Health Science, 2020
The leishmaniases are protozoan infections that are among the neglected tropical diseases (NTDs). Over one billion people are at risk of these diseases in virtually all continents. These diseases debilitate large numbers of people, keeping them from full,
R. Wamai   +3 more
semanticscholar   +1 more source

Human leishmaniasis vaccines: Use cases, target population and potential global demand

open access: yesmedRxiv, 2021
The development of vaccines against one or all forms of human leishmaniasis remains hampered by a paucity of investment, at least in part resulting from the lack of well-evidenced and agreed estimates of vaccine demand.
S. Malvolti   +4 more
semanticscholar   +1 more source

Leishmaniasis y corazón

open access: yesArchivos de Cardiología de México, 2021
As one of the neglected tropical diseases, leishmaniasis is defined as a parasitic communicable disease that is most prevalent in tropical and subtropical regions, affecting especially populations living in poverty. It has a profound negative impact on developing economies.
Alvaro Sosa-Liprandi   +11 more
openaire   +4 more sources

Leishmania: Responding to environmental signals and challenges without regulated transcription

open access: yesComputational and Structural Biotechnology Journal, 2020
Here we describe the non-canonical control of gene expression in Leishmania, a single-cell parasite that is responsible for one of the major neglected tropical diseases.
Janne Grünebast, Joachim Clos
doaj   +1 more source

Anti-Leishmanial and Immunomodulatory Effects of Epigallocatechin 3-O-Gallate on Leishmania tropica: Apoptosis and Gene Expression Profiling

open access: yesIranian Journal of Parasitology, 2019
Background: Pentavalent antimonials such as meglumine antimoniate (MA, Glucantime), are the first-line treatment against leishmaniasis, but at present, they have basically lost their efficacy. This study was aimed to explore epigallocatechin 3-O-gallate (
Morteza SADUQI   +14 more
doaj   +1 more source

Cytokines: Key Determinants of Resistance or Disease Progression in Visceral Leishmaniasis: Opportunities for Novel Diagnostics and Immunotherapy

open access: yesFrontiers in Immunology, 2019
Leishmaniasis is a parasitic disease of humans, highly prevalent in parts of the tropics, subtropics, and southern Europe. The disease mainly occurs in three different clinical forms namely cutaneous, mucocutaneous, and visceral leishmaniasis (VL).
A. Dayakar   +3 more
semanticscholar   +1 more source

Leishmaniasis [PDF]

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, 2008
SummaryLeishmaniasis is a clinically heterogeneous group of diseases, caused by infection with protozoa of the genus Leishmania. The aggressiveness of the individual species, their organ preference and the host immune status determine disease course.
openaire   +2 more sources

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