Results 81 to 90 of about 108,588 (220)

Exploring Novel Nitrofuryl‐1,3,4‐Thiadiazole‐Based Derivatives: Design, Synthesis, and Evaluation of In Vitro Leishmanicidal and Trypanocidal Activity

Archiv der Pharmazie, Volume 359, Issue 3, March 2026.
In a series of substituted 1‐[5‐(5‐nitrofuran‐2‐yl)‐1,3,4‐thiadiazol‐2‐yl]piperidine‐4‐carboxamides evaluated for in vitro antileishmanial and antitrypanosomal activity, compound 18 emerged as the most promising derivative, showing submicromolar anti‐parasitic effects targeting diverse Leishmania and Trypanosoma species and acceptable selectivity ...
Alireza Mousavi, Martina Slapničková, Maryam Norouzbahari, Sarah D'Alessandro, Parham Foroumadi, Fariba Peytam, Federica Perego, Eva Doleželová, Zahra Emamgholipour, Maliheh Barazandeh Tehrani, Seyed Esmaeil Sadat‐Ebrahimi, Elahe Hosseinzadeh, Elmira Meghrazi Ahadi, Loghman Firoozpour, Hamidreza Bijanzadeh, Nicoletta Basilico, Alena Zíková, Alireza Foroumadi   +17 more
wiley   +1 more source

Phytochemical and Biological Evaluation of Leaves, Stems, and Roots of Schinus weinmanniifolia Mart. Ex Engl.

Chemistry &Biodiversity, Volume 23, Issue 3, March 2026.
Ethanolic extracts from leaves, stems, and roots of Schinus weinmanniifolia Mart. ex Engl. were evaluated for phytochemical composition and biological activities. The extracts exhibited antioxidant, photoprotective, and antimicrobial activity, without hemolytic effects or cytotoxicity at active concentrations. Syringic acid, epicatechin, and rutin were
João Andrade, Adriana Araújo de Almeida‐Apolonio, Fabiana Gomes da Silva Dantas, José Irlan da Silva Santos, Andréia Sangalli, Melyssa Negri, Deisiany Gomes Ferreira, Claudia Andrea Lima Cardoso, Thiago Luis Aguayo de Castro, Aline dos Santos Garcia Gomes, Rhagner Bonono, Liliana Fernandes, Maria Elisa Rodrigues, Mariana Contente Rangel Henriques, Kelly Mari Pires de Oliveira   +14 more
wiley   +1 more source

Cutaneous Leishmaniasis in High‐Altitude: A Case Report From Nepal

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Leishmaniasis is a parasitic infection caused by Leishmania and spread by the bite of a sandfly, most commonly Phlebotomus. Among the three subtypes of Leishmaniasis, cutaneous leishmaniasis is the most common form. Visceral Leishmaniasis is common in Nepal whereas few cases of cutaneous leishmaniasis have been reported in migrant Nepalese ...
Eliz Aryal, Rohan Sapkota, Sunny Shrestha, Arika Baral, Santosh Sapkota, Mandish Prasad Phuyal   +5 more
wiley   +1 more source

The emergence of anthroponotic cutaneous leishmaniasis following the earthquake in southern villages of bam district, southeastern iran, 2010.

Journal of Arthropod-Borne Diseases, 2013
Background: The objective of this study was to assess the epidemiological characteristics of a new emerging focus of cutaneous leishmaniasis (CL) in southern villages of Bam District, southeastern Iran, 2010.
Mohammad Reza Aflatoonian, Iraj Sharifi, Somayeh Poursmaelian, Maryam Hakimi-Parizi, Nasser Ziaali   +4 more
doaj  

Evaluation of fluorimetry and direct visualization to interpret results of a loop-mediated isothermal amplification kit to detect Leishmania DNA

Parasites & Vectors, 2018
Background Nucleic acid amplification tests (NAATs) have proven to be advantageous in the diagnosis of leishmaniases, allowing sensitive diagnosis of: (i) cutaneous leishmaniasis in long duration lesions and (ii) visceral leishmaniasis using a less ...
Ana V. Ibarra-Meneses, Israel Cruz, Carmen Chicharro, Carmen Sánchez, Sylvain Biéler, Tobias Broger, Javier Moreno, Eugenia Carrillo   +7 more
doaj   +1 more source

Etymologia: Leishmaniasis

Emerging Infectious Diseases, 2008
Disease caused by protozoan parasites of the genus Leishmania, named in 1901 for British Army doctor William Leishman, who developed a stain to detect the agent. It is transmitted by the bite of certain species of sand fly, including the genus Lutzomyia in the New World and Phlebotomus in the Old World.
openaire   +2 more sources

Elucidating Trigonelline's Therapeutic Mechanisms for Traumatic Brain Injury Through Integrated Network Pharmacology and In Vivo Validation

CNS Neuroscience &Therapeutics, Volume 32, Issue 3, March 2026.
Trigonelline alleviates traumatic brain injury (TBI) by attenuating oxidative stress and neuroinflammation. It inhibits MAPK signaling–mediated neuronal apoptosis and reduces cerebral edema via downregulation of AQP4 and MMP‐9, thereby maintaining blood–brain barrier integrity.
Qian Zhang, Yuefan Zhang, Zhibing Song, Zixiang Tang, Guoqiang Wang, Xiang Yang, Jincai Li, Tiejun Li   +7 more
wiley   +1 more source

A Papillary Thyroid Cancer Metastasis Presented as a Ciliated Cyst in the Neck: An Unusual Presentation

Clinical Case Reports
This case highlights the diagnostic challenges of neck masses that appear benign but are malignant upon histological examination. It underscores the need for comprehensive diagnostic procedures to rule out cancer.
Ali Asilian, Mohammad Shoushtarizadeh, Sarah Seyedyousefi   +2 more
doaj   +1 more source

Leishmaniasis.

Revista de la Facultad de Medicina, Universidad Nacional de Colombia, 1948
Historia de la ulcera leishmaniásica en Colombia, y tratamiento de la Leishmaniasis por medio del difosfato de cloro ...
openaire   +2 more sources

Palpebral leishmaniasis

Clinical Case Reports
Key Clinical MessageLeishmaniasis can mimic many conditions, including hordeolum, basal cell carcinoma, and squamous cell carcinoma. The presence of kinetoplast in free‐form or intramacrophage amastigotes, ensuring us to establish the microscopic diagnosis of leishmaniasis.
Mohammad Sharifi, Tayebe Shiravi, Ali Bolouki, Mehrdad Motamed Shariati   +3 more
openaire   +3 more sources