Results 11 to 20 of about 66 (64)
Abstract Background Adolescence is marked by increased vulnerability to sleep disturbances and mood disorders. Understanding how day‐to‐day changes in sleep and mood are linked within the same individual is crucial for clarifying sleep's role in emerging internalizing disorders. However, the extent to which an adolescent's fluctuations in sleep predict
Konstantin Drexl +4 more
wiley +1 more source
Amyloid β alters vascular CaV1.2 channel spatiotemporal properties
Abstract figure legend Amyloid‐β1‐42 (Aβ1‐42) triggers a male‐specific signalling cascade influencing CaV1.2 spatiotemporal properties in cerebral vascular smooth muscle. The signalling pathway involves NADPH oxidase (NOX)‐derived reactive oxygen species (ROS) activation of protein kinase C (PKC). Aβ1‐42 can also activate protein kinase A (PKA).
Jade L. Taylor +5 more
wiley +1 more source
Soil CO2 and CH4 emissions were higher in broadleaf than conifer afforestation systems in the southeastern U.S., particularly during the growing season. Machine learning analyses identified soil temperature, moisture, and atmospheric conditions as key drivers, emphasizing that soil greenhouse gas responses critically influence the climate mitigation ...
Jianing Liang +24 more
wiley +1 more source
ABSTRACT Over the past decades, science education research has extensively examined the role of metaphors in teaching and learning science. However, much of the existing research has focused on verbal manifestations of metaphors, thereby overlooking aspects of metaphors that may occur in non‐verbal form. This study reconceptualises metaphors as dynamic
Magdalena Kersting +2 more
wiley +1 more source
Harnessing Generative AI for Sustainable Supply Chains: Lean, Circular and Green Perspectives
ABSTRACT Generative artificial intelligence is playing a significant role in the transformation of digital ecosystems by reinventing the processes of content generation, process automation, product innovation and customer experience. At the same time that these technologies are becoming more integrated into routine operations, the focus has shifted to ...
Ashutosh Singh +3 more
wiley +1 more source
We quantified the heritability of spring and autumn phenology and frost tolerance in European beech using a common‐garden experiment with 961 seedlings from half‐sib families. Spring leaf out and autumn senescence showed moderate heritability, indicating substantial adaptive potential, whereas bud and leaf frost tolerance exhibited low heritability ...
Jonas Schmeddes +10 more
wiley +1 more source
Fusion protein condensate formation via coiled‐coil domains
Abstract While recent research shows that biomolecular condensates play important roles in normal cellular processes and diseases, the driving forces in condensate formation are not well understood, especially regarding the role of structured self‐associative protein domains.
Om Prakash Narayan +5 more
wiley +1 more source
Blood Relatives: Linking Evolutionary History and Conservation of Medicinal Leeches (Hirudo spp.)
ABSTRACT Medicinal leeches of the genus Hirudo are both historically important in medicine and increasingly studied as models in ecology and biomedicine. However, the taxonomy, population structure and evolutionary history of this genus remain partially unresolved.
Gianluca Lombardo +10 more
wiley +1 more source
Abstract Intrinsically disordered regions (IDRs) play important molecular roles in cells even though they do not adopt a stable structure. Relative to structured regions, IDRs have skewed amino acid compositions favoring polar and charged amino acids. This feature is a major contributor to the biophysical behavior and in vivo activity of IDRs, but the ...
Sean M. Cascarina +3 more
wiley +1 more source
Abstract Process‐based watershed models require robust, spatially distributed data for accurate total nitrogen (TN) simulation. However, traditional calibrations are often constrained by sparse in situ monitoring networks, resulting in substantial estimation errors and biases, particularly in ungauged sub‐basins. While newly available spatial inversion
Shunping Zhou +3 more
wiley +1 more source

