Results 31 to 40 of about 253 (124)
Clinical and Translational Science, Volume 19, Issue 1, January 2026.ABSTRACT Fluoropyrimidines are a vital component of chemotherapy regimens. Deleterious DPYD variants reduce activity of dihydropyrimidine dehydrogenase, the rate‐limiting enzyme of fluoropyrimidine catabolism, resulting in reduced fluoropyrimidine clearance and elevated risk of life‐threatening toxicities.
Nihal El Rouby +33 more
wiley +1 more source
The Lemke–Howson Algorithm Solving Finite Non-Cooperative Three-Person Games in a Special Setting
DEStech Transactions on Computer Science and Engineering, 2019 We present a brief outline of an approximate method (3LP) proposed by E.G. Golshteyn for solving three-person games in mixed strategies. Similar to the 2LP-algorithm (which approximately solves bimatrix games), the solution procedure consists in the search of a global minimum of the so-called Nash function.
Evgeny Golshteyn +2 more
openaire +2 more sources
Essential Protein Identification Using FCNN and Harris Hawks Optimization
Applied Computational Intelligence and Soft Computing, Volume 2026, Issue 1, 2026.This research addresses the critical task of computationally identifying essential proteins, vital for organismal survival, disease understanding, and drug discovery. Existing methods face limitations with diverse biological data, significant class imbalance, and complex model optimization.
Muhammad Ihraz Fahmid Bhuiyan +5 more
wiley +1 more source
Resuelve: A Gauss program for solving computable general equilibrium and disequilibrium models [PDF]
This paper describes a GAUSS program that can be used, among other things, to find equilibria for computable general equilibrium models, and fix price equilibria for general non Walrasian models.
Urzúa, Carlos M.
core
Criss-cross methods: A fresh view on pivot algorithms [PDF]
, 2018 Criss-cross methods are pivot algorithms that solve linear programming problems in one phase starting with any basic solution. The first finite criss-cross method was invented by Chang, Terlaky and Wang independently.
Fukuda, Komei, Terlaky, Tamás
core
Geophysical Research Letters, Volume 52, Issue 23, 16 December 2025.Abstract The influence of elevated surface water temperature in disconnected pools of intermittent rivers on microbial metabolism within the benthic biolayer and underlying sediments remains unclear. This study investigates sediment metabolism under pool temperatures of 20°C, 30°C, and 40°C, focusing on biofilm growth, bioclogging, and reaction rates ...
Qihao Jiang +8 more
wiley +1 more source
MULTIPLE OPTIMAL SOLUTIONS IN QUADRATIC PROGRAMMING MODELS [PDF]
The problem of determining whether quadratic programming models possess either unique or multiple optimal solutions is important for empirical analyses which use a mathematical programming framework.
Paris, Quirino
core +1 more source
Swiss Political Science Review, Volume 31, Issue 4, Page 597-621, December 2025.Abstract Democratic innovations are increasingly used to counteract crisis phenomena such as citizen disengagement or disaffection. But to offer a cure, democratic innovations must be embedded within the democratic system; there must be a healthy “flow in communication” (henceforth: transmissions) between different democratic spaces.
Dannica Fleuß, Christoph Deppe
wiley +1 more source
An algorithm for the linear complementarity problem with upper and lower bounds [PDF]
Functional ...
Laan, G. van der, Talman, A.J.J.
core +1 more source
Journal of Geophysical Research: Atmospheres, Volume 130, Issue 22, 28 November 2025.Abstract Global storm resolving models (GSRMs) represent the next generation of global climate models. One of them is a 5‐km Icosahedral Nonhydrostatic Weather and Climate Model (ICON). Its high resolution means that parameterizations of convection and clouds, including subgrid‐scale clouds, are omitted, relying on explicit simulation but necessarily ...
Peter Kuma +11 more
wiley +1 more source