Results 21 to 30 of about 246 (126)
Clinical and Translational Science, Volume 19, Issue 1, January 2026.ABSTRACT Fluoropyrimidines are a vital component of chemotherapy regimens. Deleterious DPYD variants reduce activity of dihydropyrimidine dehydrogenase, the rate‐limiting enzyme of fluoropyrimidine catabolism, resulting in reduced fluoropyrimidine clearance and elevated risk of life‐threatening toxicities.
Nihal El Rouby +33 more
wiley +1 more source
Geophysical Research Letters, Volume 52, Issue 23, 16 December 2025.Abstract The influence of elevated surface water temperature in disconnected pools of intermittent rivers on microbial metabolism within the benthic biolayer and underlying sediments remains unclear. This study investigates sediment metabolism under pool temperatures of 20°C, 30°C, and 40°C, focusing on biofilm growth, bioclogging, and reaction rates ...
Qihao Jiang +8 more
wiley +1 more source
Swiss Political Science Review, Volume 31, Issue 4, Page 597-621, December 2025.Abstract Democratic innovations are increasingly used to counteract crisis phenomena such as citizen disengagement or disaffection. But to offer a cure, democratic innovations must be embedded within the democratic system; there must be a healthy “flow in communication” (henceforth: transmissions) between different democratic spaces.
Dannica Fleuß, Christoph Deppe
wiley +1 more source
Journal of Geophysical Research: Atmospheres, Volume 130, Issue 22, 28 November 2025.Abstract Global storm resolving models (GSRMs) represent the next generation of global climate models. One of them is a 5‐km Icosahedral Nonhydrostatic Weather and Climate Model (ICON). Its high resolution means that parameterizations of convection and clouds, including subgrid‐scale clouds, are omitted, relying on explicit simulation but necessarily ...
Peter Kuma +11 more
wiley +1 more source
A new algorithm for generalized fractional programs [PDF]
, 1996 A new dual problem for convex generalized fractional programs with no duality gap is presented and it is shown how this dual problem can be efficiently solved using a parametric approach.
Barros, A.I. (Ana) +3 more
core +1 more source
Water Resources Research, Volume 61, Issue 11, November 2025.Abstract The benthic biolayer is a shallow zone of reactive streambed sediments, widely believed to contribute disproportionately to whole‐stream reactions such as aerobic respiration and contaminant transformation. Quantifying the relative contribution of the biolayer to whole‐stream reactions remains challenging because it requires that hyporheic ...
Kevin R. Roche +8 more
wiley +1 more source
Geochemistry, Geophysics, Geosystems, Volume 26, Issue 11, November 2025.Abstract The Lepontine dome (European Central Alps) is constituted by basement nappes under Alpine regional Barrovian metamorphism, yet the duration and pattern of its post‐peak amphibolite‐facies cooling remain uncertain. We examine garnet‐rim compositional re‐adjustment and employ inverse multicomponent diffusion modeling to estimate apparent cooling
A. Tagliaferri +3 more
wiley +1 more source
Criss-cross methods: A fresh view on pivot algorithms [PDF]
, 2018 Criss-cross methods are pivot algorithms that solve linear programming problems in one phase starting with any basic solution. The first finite criss-cross method was invented by Chang, Terlaky and Wang independently.
Fukuda, Komei, Terlaky, Tamás
core
A new beef: An analysis of discourse coalitions in the nascent cellular agriculture policy subsystem
Review of Policy Research, Volume 42, Issue 6, Page 1404-1427, November 2025.Abstract A robust approach to examining the nature and influence of coalitions in the policy process is the Advocacy Coalition Framework (ACF), which is especially useful to study policy issues fraught with scientific and technical controversy. Yet, important gaps exist in ACF literature regarding nascent policy subsystems. Consequently, there is scant
Nikki Nadeau, Ramiro Berardo
wiley +1 more source
The Lemke–Howson Algorithm Solving Finite Non-Cooperative Three-Person Games in a Special Setting
DEStech Transactions on Computer Science and Engineering, 2019 We present a brief outline of an approximate method (3LP) proposed by E.G. Golshteyn for solving three-person games in mixed strategies. Similar to the 2LP-algorithm (which approximately solves bimatrix games), the solution procedure consists in the search of a global minimum of the so-called Nash function.
Evgeny Golshteyn +2 more
openaire +2 more sources