Longer telomere length in peripheral white blood cells is associated with risk of lung cancer and the rs2736100 (CLPTM1L-TERT) polymorphism in a prospective cohort study among women in China. [PDF]
A recent genome-wide association study of lung cancer among never-smoking females in Asia demonstrated that the rs2736100 polymorphism in the TERT-CLPTM1L locus on chromosome 5p15.33 was strongly and significantly associated with risk of adenocarcinoma ...
Xiang, Y +67 more
core +1 more source
AbstractTuna fisheries have become the most important contributor to the coastal central provinces of Vietnam since it was introduced in early 1990s. However, developing effective management guidelines for yellowfin (Thunnus albacares) and bigeye (Thunnus obesus) tuna, the main target species for longline and handline fisheries, is difficult because ...
Khanh Quoc Nguyen +7 more
openaire +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Length-weight relationship, growth pattern and Fulton condition factor for the targeted fishes.
Length-weight relationship, growth pattern and Fulton condition factor for the targeted fishes.
Md. Mahfujur Rahman (7513265) +7 more
core +1 more source
Length-dependent activation, the Frank-Starling mechanism and vascular filling therapy.
Length-dependent activation (LDA) is a cardiac cell property highlighted by the length-tension relationship (left). As the length of the cardiac cell increases, the peak force during an isometric twitch contraction increases. It is commonly admitted that
Sarah Kosta (417791) +1 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Measuring newborn foot length to identify small babies in need of extra care: a cross sectional hospital based study with community follow-up in Tanzania. [PDF]
BACKGROUND\ud \ud Neonatal mortality because of low birth weight or prematurity remains high in many developing country settings. This research aimed to estimate the sensitivity and specificity, and the positive and negative predictive values of newborn ...
Jaribu Jennie +14 more
core +1 more source
Biometric analysis offered important information on growth patterns, population differentiation, and habitat effects in trout. The present study aimed to evaluate variations among diverse ecological conditions and growth patterns across three farm sites ...
Hishani Kumari +7 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source

