Results 131 to 140 of about 2,246,388 (261)
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Physical and Mechanical Characterization of Flax Fibers: From Elementary Fiber to Yarn
FibersThis study presents a multiscale characterization of flax fibers, from elementary fibers to technical bundles and yarns, to elucidate how fiber scale attributes influence yarn mechanics.
Wafa Mahjoub, Omar Harzallah
doaj +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
EncyclopediaThis paper aims to present the phenotypic characteristics, such as length, width, circular diameter, volume, surface area to cross-sectional area ratio, surface uniformity, and surface texture, of the foodborne pathogens Salmonella enterica serovar Agona,
Ladees Al Hafi +3 more
doaj +1 more source
On Convergence in Length [PDF]
Proceedings of the National Academy of Sciences, 1945 openaire +3 more sources
A note on exponential dispersion models which are invariant under length-biased sampling [PDF]
Length-biased sampling situations may occur in clinical trials, reliability, queueing models, survival analysis and population studies where a proper sampling frame is absent.In such situations items are sampled at rate proportional to their length so ...
Bar-Lev, S.K. +1 more
core
Length-weight relationships of three estuarine fish species from Bangladesh
, 2018 Length-weight relationships of three estuarine fish species from ...
MA Hanif (17202520) +3 more
core +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source