Results 11 to 20 of about 600,595 (298)

ADVANCED OPTICAL TECHNIQUES TO EXPLORE BRAIN STRUCTURE AND FUNCTION [PDF]

open access: yesJournal of Innovative Optical Health Sciences, 2013
Understanding brain structure and function, and the complex relationships between them, is one of the grand challenges of contemporary sciences. Thanks to their flexibility, optical techniques could be the key to explore this complex network.
L. SILVESTRI   +4 more
doaj   +1 more source

α-catenin switches between a slip and an asymmetric catch bond with F-actin to cooperatively regulate cell junction fluidity

open access: yesNature Communications, 2022
By using laser tweezers, the authors show that a single α-catenin molecule does not resist force on F-actin. However, clustering of multiple molecules and force applied toward F-actin pointed end engage a molecular switch in α-catenin, which unfolds and ...
C. Arbore   +8 more
doaj   +1 more source

Vesicular Trafficking, a Mechanism Controlled by Cascade Activation of Rab Proteins: Focus on Rab27

open access: yesBiology, 2023
Vesicular trafficking is essential for the cell to internalize useful proteins and soluble substances, for cell signaling or for the degradation of pathogenic elements such as bacteria or viruses.
Camille Menaceur   +4 more
doaj   +1 more source

Highlighting In Vitro the Role of Brain-like Endothelial Cells on the Maturation and Metabolism of Brain Pericytes by SWATH Proteomics

open access: yesCells, 2023
Within the neurovascular unit, brain pericytes (BPs) are of major importance for the induction and maintenance of the properties of the blood-brain barrier (BBB) carried by the brain microvessel endothelial cells (ECs).
Camille Menaceur   +9 more
doaj   +1 more source

Assessing brain state and anesthesia level with two-photon calcium signals

open access: yesScientific Reports, 2023
Brain states, such as wake, sleep, or different depths of anesthesia are usually assessed using electrophysiological techniques, such as the local field potential (LFP) or the electroencephalogram (EEG), which are ideal signals for detecting activity ...
Núria Tort-Colet   +5 more
doaj   +1 more source

The Blood–Brain Barrier, an Evolving Concept Based on Technological Advances and Cell–Cell Communications

open access: yesCells, 2021
The construction of the blood–brain barrier (BBB), which is a natural barrier for maintaining brain homeostasis, is the result of a meticulous organisation in space and time of cell–cell communication processes between the endothelial cells that carry ...
Camille Menaceur   +3 more
doaj   +1 more source

Some counterexamples for (strong) persistence property and (nearly) normally torsion-freeness

open access: yesExamples and Counterexamples, 2023
In this article, we present some rare counterexamples, which are related to (strong) persistence property and (nearly) normally torsion-freeness of monomial ideals.
Mehrdad Nasernejad
doaj   +1 more source

Angular lens

open access: yesOptics Express, 2018
We propose a single phase-only optical element that transforms different orbital angular momentum (OAM) modes into localized spots at separated angular positions on a transverse plane. We refer to this element as an angular lens since it separates out OAM modes in a manner analogous to how a converging lens separates out transverse wave-vector modes at
Rishabh Sahu   +5 more
openaire   +6 more sources

Hydrophobic versus hydrophilic acrylic intraocular lens on posterior capsule opacification: a Meta-analysis [PDF]

open access: yesInternational Journal of Ophthalmology, 2022
AIM: To conduct a Meta-analysis pooling randomized controlled trials (RCTs) to compare hydrophobic with hydrophilic acrylic intraocular lenses in terms of posterior capsule opacification (PCO) development.
Qiong Wu, Yan Li, Lian Wu, Cong-Yi Wang
doaj   +1 more source

Miniaturization and Automation of a Human In Vitro Blood–Brain Barrier Model for the High-Throughput Screening of Compounds in the Early Stage of Drug Discovery

open access: yesPharmaceutics, 2021
Central nervous system (CNS) diseases are one of the top causes of death worldwide. As there is a difficulty of drug penetration into the brain due to the blood–brain barrier (BBB), many CNS drugs treatments fail in clinical trials.
Elisa L. J. Moya   +7 more
doaj   +1 more source

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