Results 71 to 80 of about 3,884 (198)

Immunotherapy Administration and Survival for Stage IV Melanoma Patients at Minority‐Serving Hospitals

Cancer Medicine, Volume 15, Issue 4, April 2026.
ABSTRACT Background Immunotherapy has transformed outcomes in stage IV melanoma, yet disparities in access persist. Minority‐serving hospitals (MSH) disproportionately care for socioeconomically disadvantaged and minority patients, but their impact on immunotherapy use and survival in melanoma is not well defined.
Mackenzie M. Mayhew, Zoe Hemmer, Elizabeth J. Olecki, Jacob A. Sellers, Nidhi Kuchimanchi, Lynn T. Dengel, Craig L. Slingluff Jr., Russell G. Witt   +7 more
wiley   +1 more source

Robustness of a convolutional neural network trained on dermoscopic images and challenged with close‐up images

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 4, Page 504-513, April 2026.
Summary Background and Objectives Deep learning‐convolutional neural networks (DL‐CNNs) have demonstrated high diagnostic accuracy within the domain of dermoscopy. However, many clinical settings lack dermoscopic devices, requiring reliance on close‐up images. This study evaluates the robustness of a DL‐CNN trained on dermoscopic images when challenged
Anastasia Sophie Vollmer, Julia Katharina Winkler, Katharina Susanne Kommoss, Wilhelm Stolz, Albert Rosenberger, Alexander Enk, Holger Andreas Haenssle   +6 more
wiley   +1 more source

Domänenübergreifende diagnostische Genauigkeit eines DL‐CNN: Dermatoskopie versus klinische Nahaufnahmen

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 4, Page 504-514, April 2026.
Zusammenfassung Hintergrund und Zielsetzung Deep‐learning‐basierte Convolutional Neural Networks (DL‐CNN) erzielen innerhalb der Domäne der dermatoskopischen Bildgebung eine hohe diagnostische Genauigkeit. In der klinischen Praxis stehen dermatoskopische Geräte jedoch nicht immer zur Verfügung, sodass häufig klinische Nahaufnahmen angefertigt werden ...
Anastasia Sophie Vollmer, Julia Katharina Winkler, Katharina Susanne Kommoss, Wilhelm Stolz, Albert Rosenberger, Alexander Enk, Holger Andreas Haenssle   +6 more
wiley   +1 more source

AI‐derived prognostic biomarkers from melanoma whole slide image segmentation: an initial discovery and assessment

The Journal of Pathology: Clinical Research, Volume 12, Issue 2, March 2026.
Abstract The current melanoma staging system predicts 74% of the variance in survival, with prognostic biomarkers subject to high levels of inter‐observer variation. This work assesses whether a previously developed convolutional neural network (CNN) for invasive melanoma segmentation in whole slide images (WSIs) may reveal new insights into melanoma ...
Emily L Clarke, Derek Magee, Julia Newton‐Bishop, Gerald Saldanha, William Merchant, Marlous Hall, Robert Insall, Nigel G Maher, Richard A Scolyer, Grace Farnworth, Anisah Ali, Mark Bamford, Eva Sticova, Petr Kujal, Sally O'Shea, Darren Treanor   +15 more
wiley   +1 more source

Hypothyroidism as Prognostic Factor in Cutaneous Melanoma: A 1553‐Patient Single‐Center Study

Cancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT Background Cutaneous melanoma is a rising global health concern and identifying modifiable or associated risk factors remains essential for improving prognostic stratification. Hypothyroidism, affecting approximately 5.1% of the general population in Germany, has been associated with various malignancies. This study investigates the prevalence
Julie Klose, Filipa Almeida Oliveira, Charalampos Varnava, Philipp Wiebringhaus, Grit Sophie Herter‐Sprie, Hans‐Joachim Schulze, Tobias Hirsch, Sascha Wellenbrock, Maximilian Kueckelhaus   +8 more
wiley   +1 more source

Lentigo maligna: Clinical management and histopathological diagnosis

, 2020
Lentigo maligna is a disease usually seen on sun-exposed skin in the elderly population. Usually it is situated on the face which contains anatomical and cosmetic critical structures.
Tio, Darryl C. K. S.
core  

Improvement of early recognition of lentigo maligna using dermatoscopy

, 2000
Background: The clinical differentiation between lentigo senilis/initial seborrheic keratosis and lentigo maligna on the face can be difficult. Objective: Our purpose was to determine whether dermatoscopy (eg, skin surface microscopy at 10x magnification)
Wlotzke, Uwe, Schiffner, Roman, Landthaler, Michael, Cognetta, Armand B., Stolz, Wilhelm, Vogt, Thomas, Schiffner-Rohe, Julia   +6 more
core   +1 more source

Decision Aid for Lentigo Maligna

, 2020
The Decision Aid for Lentigo Maligna was developed by members of the American Society for Dermatologic Surgery with iterative feedback from patients. It contains evidence-based information regarding LM and various treatment modalities, including surgery,
vaidya, T (via Mendeley Data)
core   +2 more sources

Chondrosarcomatous Differentiation in a Large Malignant Melanoma of the Scalp

Case Reports in Medicine, 2016
Background. Divergent differentiation in malignant melanoma is a rare phenomenon, which can lead to delayed diagnosis or misdiagnosis, impacting upon patient treatment and outcome, as well as the understanding of tumour behaviour. Case.
Colin S. Alderson, Helen E. Douglas, Rebecca Rollett, Bipin Mathew, Paolo Matteucci   +4 more
doaj   +1 more source

Increasing incidence of lentigo maligna and lentigo maligna melanoma in Catalonia

International Journal of Dermatology, 2018
AbstractBackgroundRecent epidemiological studies suggest that past data where superficial spreading melanoma was by far the most common subtype of melanoma may not reflect current patterns of sun exposure or other risk factors more involved in other subtypes of melanoma as lentigo maligna (LM) or lentigo maligna melanoma (LMM).MethodsIn order to ...
Clara Matas‐Nadal, Josep Malvehy, Jose Ramon Ferreres, Aram Boada, Domingo Bodet, Sonia Segura, Montse Salleras, Antoni Azon, Susana Bel‐Pla, Xavier Bigata, Antoni Campoy, Neus Curcó, Joan Dalmau, Manel Formigon, Alberto Gonzalez, Miquel Just, Enric Llistosella, M. Elena Nogues, Ramon Pedragosa, Josep A. Pujol, Mireia Sabat, Joan A. Smandia, Pedro Zaballos, Susana Puig, Rosa M. Martí   +24 more
openaire   +5 more sources