Results 1 to 10 of about 29,009 (218)

Effective treatment of a giant condyloma with imiquimod and HPV vaccination [PDF]

Gynecologic Oncology Reports
Background: Giant condyloma acuminata (GCA) is a sexually transmitted disease caused by human papillomavirus (HPV), mostly types 6 and 11. Only a few cases have been reported in children and young patients.
Julia Fromme, Roland Hake, Elmar Armin Joura, Monika Hampl   +3 more
doaj   +2 more sources

[Artículo traducido] Serie de 14 casos de tratamiento con imiquimod tópico al 5% en lentigo maligno: modalidades terapéuticas y claves para detectar recidivas

Actas Dermo-Sifiliográficas, 2022
Resumen: Imiquimod tópico ha sido utilizado como monoterapia o tratamiento adyuvante fuera de indicación para el lentigo maligno (LM). Nuestro objetivo es describir las modalidades de tratamiento, los resultados clínicos y el manejo de la recidiva en los
I. Poveda-Montoyo, P. Álvarez-Chinchilla, L. Schneller-Pavelescu, P. Hispán-Ocete, J. Bañuls-Roca   +4 more
doaj   +1 more source

Series of Fourteen Cases of Topical Imiquimod 5% in Lentigo Maligna: Treatment Modalities and Clues for Detecting Recurrences

Actas Dermo-Sifiliográficas, 2022
Topical imiquimod has been used off-label as monotherapy or adjuvant treatment for lentigo maligna. Our aim is to describe treatment modalities, clinical outcomes, and management of recurrence in patients receiving imiquimod for lentigo maligna.Patients ...
I. Poveda-Montoyo, P. Álvarez-Chinchilla, L. Schneller-Pavelescu, P. Hispán-Ocete, J. Bañuls-Roca   +4 more
doaj   +1 more source

Imiquimod induces apoptosis of squamous cell carcinoma (SCC) cells via regulation of A20. [PDF]

PLoS ONE, 2014
Imiquimod, a nucleoside analogue of the imidazoquinoline family, is being used to treat various cutaneous cancers including squamous cell carcinoma (SCC).
Kyung-Cheol Sohn, Zheng Jun Li, Dae-Kyoung Choi, Tiejun Zhang, Jae Woo Lim, In-Kyu Chang, Gang Min Hur, Myung Im, Young Lee, Young-Joon Seo, Jeung-Hoon Lee, Chang Deok Kim   +11 more
doaj   +1 more source

A Perspective on Imiquimod Microneedles for Treating Warts

Pharmaceutics, 2021
Warts are a common skin problem and are caused by infection with a virus. Warts are currently mainly treated by therapies involving ablating tissue or interrupting cellular division.
Tsu-Man Chiu, Ping-Chun Hsu, Mohd Yaqub Khan, Cheng-An J. Lin, Chun-Hung Lee, Tsai-Ching Hsu, Min-Hua Chen, Nobutaka Hanagata   +7 more
doaj   +1 more source

Co-Delivery of Imiquimod and Curcumin by Nanoemugel for Improved Topical Delivery and Reduced Psoriasis-Like Skin Lesions

Biomolecules, 2020
The current investigation aimed to improve the topical efficacy of imiquimod in combination with curcumin using the nanoemulsion-based delivery system through a combinatorial approach.
Mohammed S. Algahtani, Mohammad Zaki Ahmad, Ihab Hamed Nourein, Javed Ahmad   +3 more
doaj   +1 more source

Imiquimod Boosts Interferon Response, and Decreases ACE2 and Pro-Inflammatory Response of Human Bronchial Epithelium in Asthma

Frontiers in Immunology, 2021
BackgroundBoth anti-viral and anti-inflammatory bronchial effects are warranted to treat viral infections in asthma. We sought to investigate if imiquimod, a TLR7 agonist, exhibits such dual actions in ex vivo cultured human bronchial epithelial cells ...
Juan José Nieto-Fontarigo, Sofia Tillgren, Samuel Cerps, Asger Sverrild, Morten Hvidtfeldt, Sangeetha Ramu, Mandy Menzel, Adam Frederik Sander, Adam Frederik Sander, Celeste Porsbjerg, Lena Uller   +10 more
doaj   +1 more source

Case of large lentigo maligna melanoma of the scalp treated with 5% and 3.75% Imiquimod,

Anais Brasileiros de Dermatologia, 2021
The paper presents a case of lentigo maligna melanoma of the scalp in an elderly patient treated for the nodular part with surgery and the residual melanoma in situ with 5% Imiquimod and subsequently with 3.75% Imiquimod (each concentration for 4 months,
Miriam Rovesti, Alfredo Zucchi, Claudio Feliciani, Francesca Satolli   +3 more
doaj   +1 more source

Effect of Imiquimod on Tachyzoites of Toxoplasma gondii and Infected Macrophages in vitro and in BALB/c Mice

Frontiers in Cellular and Infection Microbiology, 2020
Treatment for toxoplasmosis is not completely successful because of their unwanted side effects, and new treatments are needed. Imiquimod has ability to moderate immune response and used to treat a wide variety of infections and tumors.
Leila Zaki, Fatemeh Ghaffarifar, Zohreh Sharifi, John Horton, Javid Sadraei   +4 more
doaj   +1 more source

Roles of TLR7 in activation of NF-κB signaling of keratinocytes by imiquimod. [PDF]

PLoS ONE, 2013
Imiquimod is known to exert its effects through Toll-like receptor 7 (TLR7) and/or TLR8, resulting in expression of proinflammatory cytokines and chemokines.
Zheng Jun Li, Kyung-Cheol Sohn, Dae-Kyoung Choi, Ge Shi, Dongkyun Hong, Han-Eul Lee, Kyu Uang Whang, Young Ho Lee, Myung Im, Young Lee, Young-Joon Seo, Chang Deok Kim, Jeung-Hoon Lee   +12 more
doaj   +1 more source