Results 21 to 30 of about 21,198 (196)

Immune-based biomarker accurately predicts response to imiquimod immunotherapy in cervical high-grade squamous intraepithelial lesions

open access: yesJournal for ImmunoTherapy of Cancer, 2022
Background The complete response rate of cervical high-grade squamous intraepithelial lesion (cHSIL) patients to imiquimod immunotherapy is approximately 60%. Consequently, many patients are exposed to unnecessary adverse effects of imiquimod.
Natasja Hendriks   +12 more
doaj   +1 more source

DataSheet_1_Optimized dithranol-imiquimod-based transcutaneous immunization enables tumor rejection.pdf

open access: yes, 2023
IntroductionTranscutaneous immunization (TCI) is a non-invasive vaccination method promoting strong cellular immune responses, crucial for the immunological rejection of cancer.
Sophie Luise Meiser (16917870)   +25 more
core   +1 more source

Imiquimod-induced hypertrophic lupus erythematosus-like reaction. [PDF]

open access: yes, 2022
Imiquimod is a topical immunomodulator that acts as an inducer of interferon (IFN)-a expression through Toll-like receptor (TLR)7 signaling with indications for the treatment of non-hyperkeratotic actinic keratosis of the face or scalp, superficial basal
Safadi, Mohannad G   +4 more
core   +1 more source

Management of superficial basal cell carcinoma: focus on imiquimod

open access: yes, 2009
Superficial basal cell carcinoma comprise up to 25% of all histological sub-types. They are more likely to occur on younger persons and females and although generally more common on the trunk, also occur frequently on the exposed areas of the head and ...
Raasch, Beverley, Beverly Raasch
core   +2 more sources

Imiquimod induced vitiligo‐like lesions—A consequence of modified melanocyte function

open access: yesImmunity, Inflammation and Disease, 2022
Introduction Imiquimod plays an important role in the management of condyloma and premalignant lesions. Successively, an increase of hypopigmented lesions following imiquimod application has been reported.
Haiyan Yu   +4 more
doaj   +1 more source

Systemic adverse events in imiquimod use for cervical intraepithelial neoplasia – A case series

open access: yesCase Reports in Women's Health, 2019
Treatment for cervical intraepithelial neoplasia (CIN) often consists of an excisional procedure. However, less invasive treatment methods have been explored, such as topical treatment with imiquimod cream.
Tirza Wouters   +8 more
doaj   +1 more source

The Immunomodulatory Small Molecule Imiquimod Induces Apoptosis in Devil Facial Tumour Cell Lines. [PDF]

open access: yesPLoS ONE, 2016
The survival of the Tasmanian devil (Sarcophilus harrisii) is threatened by devil facial tumour disease (DFTD). This transmissible cancer is usually fatal, and no successful treatments have been developed.
Amanda L Patchett   +4 more
doaj   +1 more source

Imiquimod cream improves photodamaged skin

open access: yesJournal of Dermatology and Dermatologic Surgery, 2022
Chronic exposure to ultraviolet light causes wrinkles and dyspigmentation. Imiquimod cream is an immune-modulator medication approved for the treatment of genital warts, actinic keratosis, and superficial basal cell carcinoma.
Suliman S Alfaraj   +2 more
doaj   +1 more source

TLR7 Activation of Macrophages by Imiquimod Inhibits HIV Infection through Modulation of Viral Entry Cellular Factors

open access: yesBiology, 2021
The Toll-like receptor (TLR) 7 is a viral sensor for detecting single-stranded ribonucleic acid (ssRNA), the activation of which can induce intracellular innate immunity against viral infections.
Feng-Zhen Meng   +6 more
doaj   +1 more source

The Complementary Role of ToF-SIMS in the Assessment of Imiquimod Permeated into the Skin from a Microemulsion Dosage Form

open access: yesAl-Mustansiriyah Journal of Pharmaceutical Sciences, 2019
The assessment of drug permeation into/across the skin is traditionally accomplished using Franz diffusion cells with subsequent analysis by conventional chromatographic methods such as HPLC and more recently using advanced imaging techniques.
Mohammed Hussain Al-Mayahy   +2 more
doaj   +1 more source

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