Results 21 to 30 of about 29,009 (218)
Peripheral inflammation is associated with remote global gene expression changes in the brain [PDF]
, 2014 Background: Although the central nervous system (CNS) was once considered an immunologically privileged site, in recent years it has become increasingly evident that cross talk between the immune system and the CNS does occur. As a result, patients with
Cavanagh, Jonathan +3 more
core +2 more sources
Imiquimod induced vitiligo‐like lesions—A consequence of modified melanocyte function
Immunity, Inflammation and Disease, 2022 Introduction Imiquimod plays an important role in the management of condyloma and premalignant lesions. Successively, an increase of hypopigmented lesions following imiquimod application has been reported.
Haiyan Yu +4 more
doaj +1 more source
Imiquimod cream improves photodamaged skin
Journal of Dermatology and Dermatologic Surgery, 2022 Chronic exposure to ultraviolet light causes wrinkles and dyspigmentation. Imiquimod cream is an immune-modulator medication approved for the treatment of genital warts, actinic keratosis, and superficial basal cell carcinoma.
Suliman S Alfaraj +2 more
doaj +1 more source
Acantholytic Pityriasis Rubra Pilaris Associated with Imiquimod 3.75% Application
Case Reports in Dermatological Medicine, 2011 Imiquimod is an immunomodulator with both antitumor and antiviral properties. It is currently available in two cream formulations as Aldara (imiquimod 5%) and the newly approved Zyclara (imiquimod 3.75%).
Natasha Atanaskova Mesinkovska +3 more
doaj +1 more source
Biology, 2021 The Toll-like receptor (TLR) 7 is a viral sensor for detecting single-stranded ribonucleic acid (ssRNA), the activation of which can induce intracellular innate immunity against viral infections.
Feng-Zhen Meng +6 more
doaj +1 more source
Clinical utility of ingenol mebutate in the management of actinic keratosis. Perspectives from clinical practice [PDF]
, 2018 Actinic keratoses (AKs) are epidermal cutaneous neoplasia observed predominantly in middle-aged and older subjects with mainly photo type I and photo type II on sun-exposed surfaces as a result of DNA damage.
Bernardini, Nicoletta +3 more
core +1 more source
Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2019 The assessment of drug permeation into/across the skin is traditionally accomplished using Franz diffusion cells with subsequent analysis by conventional chromatographic methods such as HPLC and more recently using advanced imaging techniques.
Mohammed Hussain Al-Mayahy +2 more
doaj +1 more source
Targeting GLI factors to inhibit the Hedgehog pathway [PDF]
, 2015 Hedgehog (Hh) signaling has emerged in recent years as an attractive target for anticancer therapy because its aberrant activation is implicated in several cancers. Major progress has been made in the development of SMOOTHENED (SMO) antagonists, although
Alfonsi, Romina +4 more
core +2 more sources
Human plasmacytoid dendritic cells and cutaneous melanoma [PDF]
, 2020 The prognosis of metastatic melanoma (MM) patients has remained poor for a long time. However, the recent introduction of effective target therapies (BRAF and MEK inhibitors for BRAFV600-mutated MM) and immunotherapies (anti-CTLA-4 and anti-PD-1) has ...
Bugatti, Mattia +4 more
core +2 more sources
Вопросы вирусологии, 2017 Background. Imiquimod is an imidazole derivative acting as an immunomodulator on the level of innate and adaptive immune system. Our objective was to evaluate the antiviral activity of generically reproduced imiquimod administered subcutaneously in mice ...
V. S. Smirnov, S. V. Petlenko
doaj +1 more source