Results 31 to 40 of about 21,198 (196)
Вопросы вирусологии, 2017 Background. Imiquimod is an imidazole derivative acting as an immunomodulator on the level of innate and adaptive immune system. Our objective was to evaluate the antiviral activity of generically reproduced imiquimod administered subcutaneously in mice ...
V. S. Smirnov, S. V. Petlenko
doaj +1 more source
Surgery versus 5% imiquimod for nodular and superficial basal-cell carcinoma: five year results of the SINS randomised controlled trial [PDF]
, 2016 Background: We previously reported modest clinical 3-year benefit for topical imiquimod compared with surgery for superficial or nodular basal cell carcinoma (sBCC, nBCC) at low risk sites in our non-inferiority randomised controlled SINS trial.
Miller, Paul S.J. +7 more
core +1 more source
Iraqi Journal of Pharmaceutical Sciences, 2023 Psoriasis is a chronic, inflammatory condition that primarily affects the skin, hair, and joints and is associated with significant humanistic and economic consequences. Psoriasis was induced in mice in this work using an imiquimod 5%
Raghad Abdulsalam Khaleel +1 more
doaj +1 more source
Immunomodulator loaded microneedle arrays for targeted intradermal drug delivery to skin tumors
Drug DeliveryTopical therapy with imiquimod in a cream [5% w/w imiquimod cream (Aldara™)] for the treatment of nodular basal cell carcinoma (BCC) currently results in low cure rates, attributed to low imiquimod permeation.
Akmal H. Sabri +10 more
doaj +1 more source
JPRAS Open, 2017 Topical Imiquimod is increasingly used in the treatment of lentigo maligna (LM) for patients not suitable or willing for surgery. It acts as an immune response modifier and is recommended for use with caution in patients with autoimmune disorders.
E.A. Whatling +2 more
doaj +1 more source
Imiquimod Targets Toxoplasmosis Through Modulating Host Toll-Like Receptor-MyD88 Signaling
Frontiers in Immunology, 2021 Toxoplasma gondii is a prevalent parasite of medical and veterinary importance. Tachyzoïtes and bradyzoïtes are responsible for acute and chronic toxoplasmosis (AT and CT), respectively.
Maguy Hamie +6 more
doaj +1 more source
Safety, efficacy, and patient acceptability of imiquimod for topical treatment of actinic keratoses
, 2011 Caroline Caperton, Brian BermanDepartment of Dermatology and Cutaneous Surgery, Miller School of Medicine, University of Miami, Miami, FL, USAAbstract: Imiquimod, an immune-modulating imidazoquinoline compound, has been approved in topical formulation ...
Caperton CV +3 more
core +1 more source
8-Methoxypsoralen Plus Ultraviolet A Reduces the Psoriatic Response to Imiquimod in a Murine Model
Acta Dermato-Venereologica, 2018 The effects of 8-Methoxypsoralen plus ultraviolet A (PUVA) or ultraviolet B (UVB) alone on imiquimod-induced psoriasis were examined in a mouse model.
Nitesh Shirsath +7 more
doaj +1 more source
Ameliorating Effect of Oral Guggulsterone Administration in Imiquimod-Induced Psoriasis in Mice
Iraqi Journal of Pharmaceutical Sciences, 2018 Psoriasis is a common chronic skin condition characterized by infiltration of inflammatory cells into the epidermis and altered keratinocyte differentiation.
Raghad A. Khaleel, Munaf H. Zalzala
doaj +1 more source
Advanced Science, EarlyView.This work identified CPD3a as a potent, stable C‐nucleoside cordycepin derivative. When formulated into microneedle array for topical treatment, it ameliorated psoriasis by rebalancing immunity and enhancing antioxidant defenses. ABSTRACT Psoriasis is a chronic inflammatory disorder characterized by immune dysregulation and epidermal hyperplasia ...
Wenfang Pan +7 more
wiley +1 more source