Results 31 to 40 of about 29,009 (218)

The Ameliorating Effect of Oral Paquinimod Administration against Imiquimod Induced Psoriasis-like Inflammation in Mice

Iraqi Journal of Pharmaceutical Sciences, 2023
                 Psoriasis is a chronic, inflammatory condition that primarily affects the skin, hair, and joints and is associated with significant humanistic and economic consequences. Psoriasis was induced in mice in this work using an imiquimod 5%
Raghad Abdulsalam Khaleel, Munaf Hashim Zalzala   +1 more
doaj   +1 more source

Impact of Age and Body Site on Adult Female Skin Surface pH [PDF]

, 2012
Background: pH is known as an important parameter in epidermal barrier function and homeostasis. Aim: The impact of age and body site on skin surface pH (pH(SS)) of women was evaluated in vivo.
Barbara Behm, Barland CO, Behne MJ, Behne MJ, Braun-Falco O, Choi EH, Dikstein S, Elias PM, Fluhr JW, Fluhr JW, Ghadially R, Ghadially R, Giusti F, Hachem JP, Hans Christian Korting, Hoeger PH, Kim EJ, Kocinkova AS, Korting HC, Korting HC, Kürner JM, Lambers H, Liebsch G, Mauro T, Michael Landthaler, Philipp Babilas, Posch HE, Robert Johannes Meier, Schmid-Wendtner MH, Schmuth M, Schreml S, Schreml S, Seyfarth F, Stephan Schreml, Takagi Y, Veronika Zeller, Wilhelm KP, Ye J, Yosipovitch G, Yosipovitch G, Zlotogorski A   +40 more
core   +2 more sources

Basal cell carcinoma: 10-year experience with electrochemotherapy [PDF]

, 2017
BACKGROUND: Electrochemotherapy (ECT), by combining manageable cytotoxic agents with short electric pulses, represents an effective palliative skin-directed therapy.
Alaibac, MAURO SALVATORE ALESSANDRO, Campana, LUCA GIOVANNI, Galuppo, Sara, Marconato, Roberto, Mocellin, Simone, Rossi, CARLO RICCARDO, Valpione, Sara   +6 more
core   +2 more sources

Effect of topical imiquimod as primary treatment for lentigo maligna: the LIMIT-1 study [PDF]

, 2016
Background: Topical imiquimod is sometimes used for lentigo maligna (LM) in situ melanoma instead of surgery, but frequency of cure is uncertain. Pathological complete regression (pCR) is a logical surrogate marker for cure after imiquimod, although ...
, NCRI Skin Cancer Clinical Studies Group, the U.K. Dermatology Cl, Billingham, L J, Boota, N M, Cook, M, Fox, R, Marsden, J R, Steven, N M, Wheatley, K   +7 more
core   +4 more sources

Immunomodulator loaded microneedle arrays for targeted intradermal drug delivery to skin tumors

Drug Delivery
Topical therapy with imiquimod in a cream [5% w/w imiquimod cream (Aldara™)] for the treatment of nodular basal cell carcinoma (BCC) currently results in low cure rates, attributed to low imiquimod permeation.
Akmal H. Sabri, Fiona Smith, Zachary Cater, Pratik Gurnani, Ami Nash, Victoria Brentville, Lindy Durrant, John McKenna, Joel Segal, David J. Scurr, Maria Marlow   +10 more
doaj   +1 more source

Chronic vulvar Paget’s disease: a therapeutic challenge with a review of the literature [PDF]

, 2019
Vulvar Paget’s disease is an uncommon adenocarcinoma of the female genital tract, occuring more often in postmenopausal Caucasian women and accounting for 1-2% of all vulvar malignancies. A 39-year-old female patient was examined for the erythematous and
Hatem, Bouzaiene, Ines, Zemni, Khaled, Rahal, Malek, Bouhani, Yasmine, Fertani   +4 more
core   +2 more sources

Immune thrombocytopenic purpura: A rare side effect in a patient treated with Imiquimod for lentigo maligna

JPRAS Open, 2017
Topical Imiquimod is increasingly used in the treatment of lentigo maligna (LM) for patients not suitable or willing for surgery. It acts as an immune response modifier and is recommended for use with caution in patients with autoimmune disorders.
E.A. Whatling, K. Balghari, B.W.E.M. Powell   +2 more
doaj   +1 more source

Imiquimod Targets Toxoplasmosis Through Modulating Host Toll-Like Receptor-MyD88 Signaling

Frontiers in Immunology, 2021
Toxoplasma gondii is a prevalent parasite of medical and veterinary importance. Tachyzoïtes and bradyzoïtes are responsible for acute and chronic toxoplasmosis (AT and CT), respectively.
Maguy Hamie, Rania Najm, Carine Deleuze-Masquefa, Pierre Antoine Bonnet, Jean-François Dubremetz, Marwan El Sabban, Hiba El Hajj   +6 more
doaj   +1 more source

Hedgehog signaling pathway and its targets for treatment in basal cell carcinoma [PDF]

, 2012
Basal cell carcinoma (BCC) of the skin is the most common type of cancer, and accounts for up to 40% of all cancers in the United States with a growing incidence rate in the last decades in all developed countries.
CUCCHI, DANILO, DE SMAELE, Enrico, GULINO, Alberto, OCCHIONE, MARIA ANNA   +3 more
core   +3 more sources

Exosome-delivered microRNAs promote IFN-α secretion by human plasmacytoid DCs via TLR7 [PDF]

, 2018
The excessive production of type I IFNs is a hallmark and a main pathogenic mechanism of many autoimmune diseases, including systemic lupus erythematosus (SLE).
Andreoli, Laura, Bergese, Paolo, Bosisio, Daniela, Busatto, Sara, D'Oro, Ugo, Giannello, Veronica, Salvi, Valentina, Sozzani, Silvano, Tincani, Angela, Zingoni, Alessandra   +9 more
core   +1 more source