Results 71 to 80 of about 5,863 (212)

Case report. A rare case of giant basal cell carcinoma and malignant melanoma [PDF]

, 2018
The presence of two several skin lesions in the same patient is a rare occurrence in dermatological findings. The associations of malignant melanoma (MM) and giant basal cell carcinoma (BCC) within the same patient have only been described in few cases
Izzo, L., Izzo, P., Izzo, S., Pugliese, F.   +3 more
core   +1 more source

Atypical Gene Rearrangement of the COL1A1::PDGFB Fusion in Dermatofibrosarcoma Protuberans of the Abdominal Wall: A Case Report

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT The aim of this case report is to introduce the reader to dermatofibrosarcoma protuberans (DFSP). In addition to the general characteristics of this rare skin tumor with possible metastatic potential, we also describe an atypical genetic finding that made our patient's case unique.
Jakub Bejbl, Denisa Drozdková, Martina Peřinová, Jiří Ehrmann   +3 more
wiley   +1 more source

In vitro evidence for senescent multinucleated melanocytes as a source for tumor-initiating cells [PDF]

, 2015
Oncogenic signaling in melanocytes results in oncogene-induced senescence (OIS), a stable cell-cycle arrest frequently characterized by a bi- or multinuclear phenotype that is considered as a barrier to cancer progression.
Bröcker, E.-B., Haferkamp, S., Hufnagel, A.L., Kneitz, S., Leikam, C., Meierjohann, S., Murphy, D.J., Mühling, B., Nanda, I., Otto, C., Schartl, M., Schmid, M., Wagner, T.U.   +12 more
core   +2 more sources

Melanoma: Pathogenesis and Targeted Therapy

MedComm, Volume 7, Issue 1, January 2026.
The treatment landscape for advanced melanoma has evolved significantly. BRAF–MEK inhibitor combinations are standard for BRAF‐mutant melanoma, whereas targeting NRAS mutations is more challenging, with MEK inhibitors like tunlametinib emerging as an option.
Yang Fu, Jie Liu, Zeming Mo, Bin Wang, Yaotiao Deng, Yu Jiang   +5 more
wiley   +1 more source

Association between confocal morphologic classification and clinical phenotypes of multiple primary and familial melanomas [PDF]

, 2018
Importance: The improved knowledge of clinical, morphologic, and epidemiologic heterogeneity of melanoma in the context of multiple primary and familial melanomas may improve prevention, diagnosis, and prognosis of melanoma.
Aguilera, Paula, Alarcon, Ivette, Alós i Hernández, Llúcia, Badenas Orquin, Celia, Bonamigo, Renan Rangel, Brito, Johanna, Carrera Álvarez, Cristina, Grazziotin, Thais Corsetti, Malvehy, J. (Josep), Potrony Mateu, Míriam, Puig Butillé, Joan Anton, Puig i Sardà, Susana   +11 more
core   +1 more source

Lateral Release – A technique for medium to large scalp lesions

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Julian Kött, Daniel Czesla, Moritz Felcht   +2 more
wiley   +1 more source

Evaluation of Multiple Tissue Levels Frequently Upstages Patients With Clinically Localized Thin Primary Cutaneous Melanoma

Journal of Cutaneous Pathology, Volume 53, Issue 1, Page 71-80, January 2026.
ABSTRACT Background Breslow thickness (BT), ulceration, and microsatellitosis are critical prognostic parameters for cutaneous melanoma staging. These parameters can vary depending on the number of tissue levels examined from individual paraffin blocks.
Louise A. Jackett, James P. Gullifer, Richard A. Scolyer   +2 more
wiley   +1 more source

Folliculotropism in head and neck lentigo maligna and lentigo maligna melanoma

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, 2020
SummaryBackgroundLentigo maligna (LM) and lentigo maligna‐melanoma (LMM) are histotypes of melanoma arising in skin with cumulative solar radiation damage. The extension of atypical melanocytes to the hair follicle (folliculotropism) is a histopathological feature of LM/LMM. Its role has not been totally clarified, but it may be correlated to treatment
Emi Dika, Martina Lambertini, Annalisa Patrizi, Cosimo Misciali, Federica Scarfì, Giovanni Pellacani, Victor Desmond Mandel, Francesca Di Tullio, Ignazio Stanganelli, Johanna Chester, Shaniko Kaleci, Daniela Massi, Vincenzo De Giorgi, Elisa Cinotti, Pietro Rubegni, Jean Luc Perrot, Francesca Farnetani   +16 more
openaire   +8 more sources

Melanoma Diagnosis in the Mihm Era—And Beyond

Journal of Cutaneous Pathology, Volume 53, Issue 1, Page 16-22, January 2026.
ABSTRACT During the illustrious career of Martin C. Mihm Jr., MD, the diagnosis of melanoma underwent significant changes, to which he made many contributions. In early descriptions, melanomas were fungating tumor masses that were obviously malignant, and highly lethal. In seminal work by Dr. Mihm and his mentor, Wallace H.
David E. Elder
wiley   +1 more source

'This isn't what mine looked like': a qualitative study of symptom appraisal and help seeking in people recently diagnosed with melanoma. [PDF]

, 2014
OBJECTIVE: To explore symptom appraisal and help-seeking decisions among patients recently diagnosed with melanomas, and to compare experiences of people with 'thinner' (2 mm) melanomas, as thickness at diagnosis is an important prognostic feature ...
Birt, Linda, Burrows, Nigel, Campbell, Christine, Cavanagh, Gina, Cavers, Debbie, Emery, Jon, MacKie, Rona, Scott, Suzanne, Walter, Fiona M, Weller, David   +9 more
core   +4 more sources