Assessment of the Adjuvant Effects of Lentinan on the Tuberculosis Subunit Vaccine BG [PDF]
VaccinesObjectives: This study aims to assess the adjuvant effects of lentinan and its combination with Mn(J), a manganese-based colloidal adjuvant, on the BG (fusion protein BfrB-GrpE of Mycobacterium tuberculosis) subunit vaccine.
Shuai Zhou +6 more
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Lentinan has a beneficial effect on cognitive deficits induced by chronic Toxoplasma gondii infection in mice [PDF]
Parasites & Vectors, 2023 Background Toxoplasma gondii (T. gondii) is increasingly considered a risk factor for neurodegenerative diseases. However, there is only limited information on the development of drugs for T. gondii infection.
Shuxi Liu +12 more
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Lentinan inhibits colorectal cancer stemness by binding CD133 and suppressing the CD133/p85/p-AKT signaling axis [PDF]
Frontiers in PharmacologyBackgroundColorectal cancer (CRC) ranks third in the global cancer incidence rate worldwide. Cancer stem cells (CSCs) are key drivers of CRC recurrence, metastasis, and therapy resistance, while therapies against them remain limited.
Yan Liu +16 more
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Prognostic model for gastric cancer patients with COVID-19 and network pharmacology study on treatment by lentinan [PDF]
Scientific ReportsPatients with gastric cancer (GC) are more susceptible to coronavirus disease 2019 (COVID-19), which further worsens their already challenging prognosis. However, there are no effective treatment options for these patients. Lentinan is a potent bioactive
Sitong Zhou, Hao Sun
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Lentinan promotes the root of Brassica CampestrisL. [PDF]
Brazilian Archives of Biology and Technology, 2015 The aim of this work was to study the effect of lentinan on Brassica campestris L (rape). Spraying on the leaves of lentinan B. campestris L. at 0.05×10-6 g ml-1 concentration significantly promoted the root elongation (P＜0.05). The results for the first
Guoyun Zhang +6 more
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Lentinan Reduces Transmission Efficiency of COVID-19 by Changing Aerodynamic Characteristic of Exhaled SARS-CoV-2 Aerosols in Golden Hamsters [PDF]
MicroorganismsLentinan (LNT) was found to reduce the aerosol transmission rate between golden hamsters from 100% (9/9) to 44.4% (4/9). The viral loads in the respiratory system, including the nasal turbinate, trachea, and lung, were significantly reduced in the ...
Cheng Zhang +9 more
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Effect of lentinan for advanced prostate carcinoma [PDF]
Hinyokika kiyo. Acta urologica Japonica, 1994 進行前立腺癌を封筒法で2群に分け, L群はテガフールを含む内分泌化学療法にレンチナンを併用, C群は, レンチナン(-)以外はL群と同様の治療を行った。L群33例の5年生存率43%, 50%生存期間は48ヵ月, C群36例の5年生存率は29%, 50%生存期間は35ヵ月で, L群は有意 ...
中込, 一彰 +9 more
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Lentinan enhances CAR-T cell potency in solid tumors by optimizing T cell differentiation [PDF]
Frontiers in ImmunologyCAR-T cell therapy has demonstrated remarkable success in treating hematologic malignancies; however, its efficacy in solid tumors remains constrained.
Xiangyun Niu +11 more
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Supplementation with Lentinan Improves the Colostrum Quality of Holstein Dairy Cows and the Immunity and Antioxidant Capacity of Newborn Calves [PDF]
AnimalsThe aim of this study was to evaluate the effects of lentinan (LNT) on the quality of colostrum produced by perinatal dairy cows and the health status of their newborn calves. A total of 40 expectant Holstein cows, matched for parity and expected date of
Yinghao Huang +8 more
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Fermentation, 2023 Lentinan has important applications in the food and medicine fields. Fermenting Lentinula edodes with Bacillus subtilis natto increased the lentinan extraction yield by 87.13% and greatly altered the molecular structure and antioxidant activity of ...
Mengyue Xu +6 more
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