Results 21 to 30 of about 2,093 (209)

Combined Effect of Lentinan and Cisplatin on Cytokines IL-6, TNF-α, and TGF-β in Tumor Therapy

International Journal of Polymer Science, 2019
Lentinan is a biologically active ingredient isolated from the fruiting body of Lentinula edodes (shiitake) and has antitumor properties. Cytokines, at the same time, are a key factor in regulating immune responses in physiological and pathological ...
Xu-dong Liu, Min Li, Wan-xiang Li, Qing-yu Wang, Hong-xia Zhang   +4 more
doaj   +2 more sources

The effect of lentinan on the resistance of mice to Mesocestoides corti

Parasitology Research, 1988
CBA/H mice were given the immunomodulator lentinan in multiple, ascending doses before (prophylactic) or after (therapeutic) inoculation with tetrathyridia of Mesocestoides corti or as a single prophylactic dose. The latter was without effect, but increasing multiple prophylactic and therapeutic doses of lentinan resulted in a marked reduction in the ...
White, T.R., Thompson, R.C.A., Penhale, W.J., Chihara, G.   +3 more
openaire   +3 more sources

Chemo-Immunotherapy Using Lentinan for the Treatment of Gastric Cancer with Liver Metastases

Medical Sciences, 2016
Gastric cancer is the third leading cause of cancer-related mortality worldwide. Systemic chemotherapy is the main treatment option for advanced gastric cancer when the tumor is inoperable.
Kenji Ina, Ryuichi Furuta, Takae Kataoka, Satoshi Kayukawa, Hiroko Ina, Masahiko Yoneda   +5 more
doaj   +2 more sources

[Effect of lentinan for advanced prostate carcinoma]. [PDF]

Hinyokika kiyo. Acta urologica Japonica, 1994
A prospective, randomized multi-center study was conducted to assess the clinical effectiveness of Lentinan, an immunomodulatory agent, in the metastatic prostate cancer. Of seventy-five patients enrolled from July 1987 to June 1992, 69 were eligible. All patients received hormonal therapy and chemotherapy using Tegafur p.o. at a dose of 400-800 mg/day.
K, Tari, I, Satake, K, Nakagomi, K, Ozawa, F, Oowada, Y, Higashi, T, Negishi, T, Yamada, H, Saito, K, Yoshida   +9 more
openaire   +2 more sources

Inhibitory Effect and Mechanism of Lentinan on Colitis-Associated Colorectal Cancer Induced by AOM/DSS Through IL-6/STAT3 Pathway [PDF]

Zhongliu Fangzhi Yanjiu
ObjectiveTo investigate the inhibitory effect and mechanism of lentinan on colitis-associated colorectal cancer (CAC) induced by azomethane (AOM)/dextran sulfate sodium salt (DSS) through the IL-6/ STAT3 pathway. MethodsC57BL/6 mice were randomly divided
Junjie LIU, Jia LIANG, Tianshu PANG, Jialong XUE, Dechun LIU   +4 more
doaj   +2 more sources

Effects of Ultrasound Modification with Different Frequency Modes on the Structure, Chain Conformation, and Immune Activity of Polysaccharides from Lentinus edodes

Foods, 2022
The aim of this study was to investigate the effects of ultrasound with different frequency modes on the chemical structure, chain conformation, and immune activity of lentinan from Lentinus edodes; the structure–activity relationship of lentinan was ...
Yu Hua, Haihui Zhang, Qian Fu, Yuqin Feng, Yuqing Duan, Haile Ma   +5 more
doaj   +1 more source

Protective Effects of Lentinan Against Lipopolysaccharide-Induced Mastitis in Mice

Frontiers in Pharmacology, 2021
Mastitis is a worldwide production disease in dairy cows, which mainly affects milk yield, causing huge economic losses to dairy farmers. Lentinan is a kind of polysaccharide extracted from Lentinus edodes, which has no toxicity and possesses various ...
Huifang Yin, Huifang Yin, Huifang Yin, Guanhong Xue, Ailing Dai, Ailing Dai, Ailing Dai, Haichong Wu, Haichong Wu, Haichong Wu   +9 more
doaj   +1 more source

The Use of Lentinan for Treating Gastric Cancer [PDF]

Anti-Cancer Agents in Medicinal Chemistry, 2013
Natural compounds containing fungal β-glucans have been used to improve general health for thousands of years in China and Japan. Lentinan, the backbone of β-(1, 3)-glucan with β-(1, 6) branches, is one of the active ingredients purified from Shiitake mushrooms and has been approved as a biological response modifier for the treatment of gastric cancer ...
Ina, Kenji, Kataoka, Takae, Ando, Takafumi   +2 more
openaire   +2 more sources

Anti-Influenza Effect and Mechanisms of Lentinan in an ICR Mouse Model

Frontiers in Cellular and Infection Microbiology, 2022
Influenza virus is a serious threat to global human health and public health security. There is an urgent need to develop new anti-influenza drugs. Lentinan (LNT) has attracted increasing attention in recent years.
Huan Cui, Huan Cui, Cheng Zhang, Cheng Zhang, Chunmao Zhang, Zhuming Cai, Ligong Chen, Zhaoliang Chen, Zhaoliang Chen, Kui Zhao, Sina Qiao, Yingchun Wang, Lijia Meng, Shishan Dong, Juxiang Liu, Zhendong Guo   +15 more
doaj   +1 more source

DataSheet1_Protective Effects of Lentinan Against Lipopolysaccharide-Induced Mastitis in Mice.ZIP

, 2021
Mastitis is a worldwide production disease in dairy cows, which mainly affects milk yield, causing huge economic losses to dairy farmers. Lentinan is a kind of polysaccharide extracted from Lentinus edodes, which has no toxicity and possesses various ...
Guanhong Xue (11475322), Huifang Yin (3695302), Ailing Dai (11475325), Haichong Wu (5673227)   +3 more
core   +1 more source