Results 11 to 20 of about 3,530 (206)

Lentinan protects Caenorhabditis elegans against fluopyram-induced toxicity through DAF-16 and SKN-1 pathways

Ecotoxicology and Environmental Safety, 2023
Fluopyram, a SDH inhibitor fungicide, is widely used in agriculture to control fungi and nematodes. However, fluopyram has been proved toxic that caused damage to organs through oxidative stress.
Huimin Liu, Bingjie Liu, Siqi Zhang, Miao Fan, Xiaoxue Ji, Shouan Zhang, Zhongtang Wang, Kang Qiao   +7 more
doaj   +1 more source

Effects of Ultrasound Modification with Different Frequency Modes on the Structure, Chain Conformation, and Immune Activity of Polysaccharides from Lentinus edodes

Foods, 2022
The aim of this study was to investigate the effects of ultrasound with different frequency modes on the chemical structure, chain conformation, and immune activity of lentinan from Lentinus edodes; the structure–activity relationship of lentinan was ...
Yu Hua, Haihui Zhang, Qian Fu, Yuqin Feng, Yuqing Duan, Haile Ma   +5 more
doaj   +1 more source

Intestinal anti-inflammatory activity of lentinan: influence on IL-8 and TNFR1 expression in intestinal epithelial cells. [PDF]

PLoS ONE, 2013
Inflammatory bowel disease (IBD) is characterized by chronic inflammation of the gastrointestinal tract. It is unknown whether β-1,3;1,6-glucan can induce immune suppressive effects.
Yosuke Nishitani, Ling Zhang, Masaru Yoshida, Takeshi Azuma, Kazuki Kanazawa, Takashi Hashimoto, Masashi Mizuno   +6 more
doaj   +1 more source

Protective Effects of Lentinan Against Lipopolysaccharide-Induced Mastitis in Mice

Frontiers in Pharmacology, 2021
Mastitis is a worldwide production disease in dairy cows, which mainly affects milk yield, causing huge economic losses to dairy farmers. Lentinan is a kind of polysaccharide extracted from Lentinus edodes, which has no toxicity and possesses various ...
Huifang Yin, Huifang Yin, Huifang Yin, Guanhong Xue, Ailing Dai, Ailing Dai, Ailing Dai, Haichong Wu, Haichong Wu, Haichong Wu   +9 more
doaj   +1 more source

Safety and efficacy of lentinan nasal drops in patients infected with the variant of COVID-19: a randomized, placebo-controlled trial

Frontiers in Pharmacology, 2023
Objective: Lentinan has antiviral, anti-tumor, immunomodulatory, stimulating interferon production, and other pharmacological effects. Previous animal experiments have shown that lentinan nasal drops can assist [Corona Virus Disease 2019) COVID-19 ...
Wenhan Fan, Benming You, Xinyu Wang, Xu Zheng, Aijing Xu, Yangang Liu, Haoran Peng, Wei Yin, Mingxiao Xu, Xu Dong, Yayun Liu, Ping Zhao, Xuesong Liang   +12 more
doaj   +1 more source

Structure-functional activity relationship of β-glucans from the perspective of immunomodulation : a mini-review [PDF]

, 2020
β-Glucans are a heterogeneous group of glucose polymers with a common structure comprising a main chain of β-(1,3) and/or β-(1,4)-glucopyranosyl units, along with side chains with various branches and lengths.
Baruah, Sri Kartik, Bossier, Peter, Cox, Eric, Han, Biao, Vanrompay, Daisy   +4 more
core   +2 more sources

Effects of Lentinan on Endothelial Cell Activity, Inflammatory Response, Endoplasmic Reticulum Stress, and Apoptosis in Sepsis

Advances in Polymer Technology, 2020
The aim of this study is to explore the protective effects of lentinan on endoplasmic reticulum stress, inflammation, and apoptosis in sepsis endothelial cells. Firstly, lentinan was extracted, purified, and analyzed.
Yan Xu, Yeping Du
doaj   +1 more source

Anti-Influenza Effect and Mechanisms of Lentinan in an ICR Mouse Model

Frontiers in Cellular and Infection Microbiology, 2022
Influenza virus is a serious threat to global human health and public health security. There is an urgent need to develop new anti-influenza drugs. Lentinan (LNT) has attracted increasing attention in recent years.
Huan Cui, Huan Cui, Cheng Zhang, Cheng Zhang, Chunmao Zhang, Zhuming Cai, Ligong Chen, Zhaoliang Chen, Zhaoliang Chen, Kui Zhao, Sina Qiao, Yingchun Wang, Lijia Meng, Shishan Dong, Juxiang Liu, Zhendong Guo   +15 more
doaj   +1 more source

Mushroom Bioactive Molecules as Anticancerous Agents: An Overview. [PDF]

Food Sci Nutr
This review discusses the molecular mechanisms through which these compounds inhibit cancer progression, including the induction of reactive oxygen species, inhibition of mitotic kinase and angiogenesis, and suppression of topoisomerase activity. By providing the latest insights on these anti‐tumor agents and their pharmacological actions, our review ...
Ikram A, Ibrahim NA, Arshad MT, Fatima A, Taseer AA, Hussain MF, Abdullah Z, Basher NS, Abdullahi MA, Al-Farga A, Al-Duais MA.   +10 more
europepmc   +2 more sources

Lentinan alleviates arsenic-induced hepatotoxicity in mice via downregulation of OX40/IL-17A and activation of Nrf2 signaling

BMC Pharmacology and Toxicology, 2022
Background Arsenic, existing ubiquitously in soil, drinking water, or food, is well known to be an environmental pollutants concerned by European Food Safety Authority.
Yuan Yang, Shuang Song, Yuanyuan Nie, Rong Chen, Peng Chen   +4 more
doaj   +1 more source