Results 81 to 90 of about 3,530 (206)

Can lactoferrin modulate the immunostimulant activity of levamisole in rats [PDF]

, 2014
Objective: The aim of this study was to study the immunomodulatory activity improvement of levamisole by using lactoferrin when applied to immunosuppressed rat model.
Wafaa Abdou Mohamed Mohamed
core   +1 more source

PI3K/AKT/mTOR Axis in Cancer: From Pathogenesis to Treatment

MedComm, Volume 6, Issue 8, August 2025.
The PI3K/AKT/mTOR signaling axis is crucial in cancer progression, regulating cell growth, survival, and metabolism. Often hyperactivated through mutations or loss of tumor suppressors such as PTEN, this pathway promotes cancer cell proliferation and survival by inhibiting apoptosis and activating mTOR, which drives protein synthesis and suppresses ...
Mingyang Jiang, Ke Zhang, Zhenwang Zhang, Xinran Zeng, Zihang Huang, Peizhuo Qin, Zhilin Xie, Xue Cai, Milad Ashrafizadeh, Yu Tian, Ruqiong Wei   +10 more
wiley   +1 more source

Shiitake mushroom-induced flagellate dermatitis: Case report

Journal of Dermatology and Dermatologic Surgery, 2020
Shiitake mushroom (SM)-induced flagellate dermatitis follows the ingestion of undercooked SMs. Pathogenesis is thought to be a delayed-type hypersensitivity reaction to lentinan, a heat-sensitive polysaccharide found in SM. Eruption is self-resolving and
Abdullah Aleisa, Natalia Plotnikova
doaj   +1 more source

Optimised quantification method for yeast-derived 1,3-β- d -glucan and α- d -mannan [PDF]

, 2018
The polysaccharides 1,3-β-d-glucan and α-d-mannan show numerous beneficial effects for the health of humans and animals. For several years, an increasing number of glucan- and mannan-containing products intended for food and feed applications are ...
Amadò, Renato, Arrigoni, Eva, Freimund, Stefan, Janett, Sandro   +3 more
core  

Harnessing the Nutritional Value, Therapeutic Applications, and Environmental Impact of Mushrooms

Food Science &Nutrition, Volume 13, Issue 7, July 2025.
Mushrooms are highly nutritious, packed with vitamins, minerals, antioxidants, essential amino acids, and bioactive compounds. They offer various health benefits, including boosting immunity, reducing inflammation, and supporting gut and cardiovascular health. Rich in carbohydrates, quality protein, essential fatty acids, and both soluble and insoluble
Solomon Fitsum, Desta Berhe Sbhatu, Gebreselema Gebreyohannes   +2 more
wiley   +1 more source

Evaluation of Ganoderma lucidum strains for the production of bioactive components and their potential use as antimicrobial agents [PDF]

, 2015
In the present study, mycelial biomass of Ganoderma lucidum strains was produced in mushroom complete media under optimized culture conditions of temperature, pH, agitation and the fruiting bodies were raised on wheat straw supplemented with 5 per cent ...
Kapoor, Shammi, Kaur, Harsimran, Khanna, P.K., Sharma, Shivani   +3 more
core   +2 more sources

Lentinan progress in inflammatory diseases and tumor diseases

European Journal of Medical Research
AbstractShiitake mushrooms are a fungal food that has been recorded in Chinese medicine to nourish the blood and qi. Lentinan (lLNT) is an active substance extracted from shiitake mushrooms with powerful antioxidant, anti-inflammatory, anti-tumor functions.
Guangda Zhou, Haiyan Liu, Ying Yuan, Qian Wang, Lanping Wang, Jianghua Wu   +5 more
openaire   +3 more sources

Lentinan: clinical benefit in the management of systemic malignancies [PDF]

Surgery Today, 2013
Sunagawa et al. [1] have provided interesting data in their recent article. Lentinan may also exert significant antineoplastic effects against other systemic malignancies. For instance, lentinan is of clinical benefit in the management of esophageal malignancies.
openaire   +2 more sources

Effects of Lentinan on Cytotoxic Functions of Human Lymphocytes

Immunopharmacology and Immunotoxicology, 1986
The in vitro effects of lentinan on natural killer (NK), antibody-dependent cell-mediated cytotoxicity (ADCC), lectin-dependent cell-mediated cytotoxicity (LDCC) and mitogen-induced blast transformation were studied in patients with solid tumors and chronic lymphocytic leukemia (CLL).
G, Péter, V, Károly, B, Imre, F, János, Y, Kaneko   +4 more
openaire   +2 more sources

Lentinan protects pancreatic β cells from STZ‐induced damage

Journal of Cellular and Molecular Medicine, 2016
AbstractPancreatic β‐cell death or dysfunction mediated by oxidative stress underlies the development and progression of diabetes mellitus (DM). In this study, we evaluated the effect of lentinan (LNT), an active ingredient purified from the bodies of Lentinus edodes, on pancreatic β‐cell apoptosis and dysfunction caused by streptozotocin (STZ) and the
Zhang, Yaqin, Mei, Hongliang, Shan, Wei, Shi, Li, Chang, Xiaoai, Zhu, Yunxia, Chen, Fang, Han, Xiao   +7 more
openaire   +2 more sources