Results 231 to 240 of about 411,689 (282)

Preclinical toxicity analyses of lentiviral vectors expressing the HIV-1 LTR-specific designer-recombinase Brec1. [PDF]

PLoS One
Beschorner N, Künzle P, Voges M, Hauber I, Indenbirken D, Nakel J, Virdi S, Bradtke P, Lory NC, Rothe M, Paszkowski-Rogacz M, Buchholz F, Grundhoff A, Schambach A, Thirion C, Mittrücker HW, Schulze Zur Wiesch J, Hauber J, Chemnitz J.   +18 more
europepmc   +1 more source

Continuous manufacturing of lentiviral vectors using a stable producer cell line in a fixed-bed bioreactor. [PDF]

Mol Ther Methods Clin Dev
Stibbs DJ, Silva Couto P, Takeuchi Y, Rafiq QA, Jackson NB, Rayat ACME.   +5 more
europepmc   +1 more source

In vivo CAR T-cell generation in nonhuman primates using lentiviral vectors displaying a multidomain fusion ligand.

Blood
Nicolai CJ, Parker MH, Qin J, Tang W, Ulrich-Lewis JT, Gottschalk RJ, Cooper SE, Hernandez Lopez SA, Parrilla D, Mangio RS, Ericson NG, Brandes AH, Umuhoza S, Michels KR, McDonnell MM, Park LY, Shin S, Leung WH, Scharenberg AM, Kiem HP, Larson RP, Beitz LO, Ryu BY.   +22 more
europepmc   +1 more source

Use of Lentiviral Vectors in Vaccination

Expert Review of Vaccines, 2021
International audienceIntroduction: Lentiviral vectors have emerged as powerful vectors for vaccination, due to their high efficiency to transduce dendritic cells and to induce long-lasting humoral immunity, CD8 + T cells, and effective protection in ...
Laleh Majlessi, Pierre Charneau
exaly   +2 more sources

Some of the next articles are maybe not open access.

Related searches:

Lentiviral Vectors

2005
We review the use of lentiviral vectors in current human gene therapy applications that involve genetic modification of nondividing tissues with integrated transgenes. Safety issues, including insertional mutagenesis and replication-competent retroviruses, are discussed.
Nils, Loewen, Eric M, Poeschla
openaire   +2 more sources

Lentiviral Vectors

2011
Lentiviral vectors have evolved over the last decade as powerful, reliable, and safe tools for stable gene transfer in a wide variety of mammalian cells. Contrary to other vectors derived from oncoretroviruses, they allow for stable gene delivery into most nondividing primary cells.
Giry-Laterrière M, Verhoeyen E, Salmon P   +2 more
openaire   +3 more sources

Lentiviral Vector Targeting

2002
After more than a decade of consternation over the lack of convincing efficacy data from the early gene therapy clinical trials, the recent reports of CAVAZZANA et al. (2000) and ABONOUR et al. (2000) have brought to gene therapists and their patients a new wave of optimism.
A, Larochelle, K W, Peng, S J, Russell
openaire   +2 more sources

Nonprimate Lentiviral Vectors

2002
Advances in the nascent field of gene therapy have created a demand for gene transfer vehicles that are capable of safely and stably delivering genes to both dividing and nondividing cells. Retroviral vectors, by virtue of their ability to permanently integrate genes of interest into the target cell genome, have played a prominent role in much of the ...
M A, Curran, G P, Nolan
openaire   +2 more sources

Immune Responses to Lentiviral Vectors

Current Gene Therapy, 2007
Efficient delivery and sustained expression of a therapeutic gene into human tissues are the requisite to accomplish the high expectations of gene therapy. A major challenge has concerned development of gene transfer systems capable of efficient cell transduction and transgene expression without harm to the recipient.
FOLLENZI, Antonia, SANTAMBROGIO L, ANNONI A.   +2 more
openaire   +3 more sources

Production and Titration of Lentiviral Vectors

Current Protocols in Neuroscience, 2010
AbstractLentiviral vectors have emerged over the last decade as powerful, reliable, and safe tools for stable gene transfer in a wide variety of mammalian cells. Unlike other vectors derived from oncoretroviruses, they allow for stable gene delivery into most nondividing primary cells, including neurons.
Barde, Isabelle, Salmon, Patrick, Trono, Didier   +2 more
openaire   +4 more sources