Results 201 to 210 of about 172,662 (343)

Editorial: Gene Therapy for the Central and Peripheral Nervous System

open access: yesFrontiers in Molecular Neuroscience, 2018
Andrew P. Tosolini, George M. Smith
doaj   +1 more source

Lentivirus-mediated downregulation of hypothalamic insulin receptor expression

open access: green, 2007
Claudia A. Grillo   +10 more
openalex   +1 more source

Astrocytic PCBP1 Suppresses Ferroptosis to Restore Glutamatergic Homeostasis and Mitigate Stress‐Induced Depression in Male Mice

open access: yesAdvanced Science, EarlyView.
This study demonstrates that polyC‐RNA‐binding protein 1 (PCBP1) in ventral hippocampal astrocytes modulates depressive‐like behaviors by regulating glutathione peroxidase 4‐mediated ferroptosis and synaptic glutamatergic transmission. PCBP1 overexpression intervention in the chronic unpredictable mild stress model rescues behavioral deficits ...
Jinyu Zhang   +15 more
wiley   +1 more source

TRIM24 promotes proliferation and metastasis of gastric cancer via mediating NRBP1 ubiquitination. [PDF]

open access: yesCell Death Dis
Weng C   +13 more
europepmc   +1 more source

Cancer Stem Cells Shift Metabolite Acetyl‐Coenzyme A to Abrogate the Differentiation of CD103+ T Cells

open access: yesAdvanced Science, EarlyView.
Lei et al. demonstrate that cancer stem cells (CSCs) play a pivotal role in impairing the differentiation of CD103+ T cells in patients with non‐small‐cell lung cancer. The key mechanism involves CSC‐derived acetyl‐CoA, which disrupts CD103+ T cell differentiation by sequentially inducing acetylation and ubiquitination of the Blimp‐1 protein. Targeting
Jiaxin Lei   +10 more
wiley   +1 more source

Transmembrane protein oligomers of caprine arthritis-encephalitis lentivirus are immunodominant in goats with progressive arthritis [PDF]

open access: bronze, 1992
T C McGuire   +5 more
openalex   +1 more source

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