Results 221 to 230 of about 172,662 (343)

Uncoupling Metastasis and Epithelial‐to‐Mesenchymal Transition in sgP19/kRAS‐Driven Spontaneous Metastatic Liver Tumor Model

Advanced Science, EarlyView.
The article first reported that a murine mixed typical intrahepatic cholangiocarcinoma (iCCA)/sarcomatoid iCCA liver tumor model with 100% incidence of spontaneous extrahepatic metastasis and confirmed the occurrence of in mouse iCCA. Most importantly, EMT induced by the TGF‐β/ZEB1 axis does not influence tumor development or distant metastasis in this
Jingwen Wang, Zijing Xu, Lei Xu, Lishan Wang, Jiahao Geng, Xue Wang, Meng Xu, Daphne Superville, Melissa Reeves, Matthias Evert, Diego F. Calvisi, Xin Chen, Xinhua Song   +12 more
wiley   +1 more source

Loss of KDM5A-mediated H3K4me3 demethylation promotes aberrant neural development by Wnt/β-catenin pathway activation. [PDF]

Cell Death Dis
Li J, Liang Y, Cao Z, Xie Q, Gu X, Ma P, Li L, Ren W, Fu Y, Liu Z, Wang Y, Zhang T, Yang H, Yang S, Xie J.   +14 more
europepmc   +1 more source

Corrigendum to “Development of traceable international standard materials using sequence-customized lentivirus, modeled on SARS-CoV-2 nucleic acid amplification tests, and validation through a pilot external quality assessment” [J Infect Chemother 31 (5) 2025 102694] [PDF]

Mizuki Sugawara Itano, Kotaro Aoki, Haruka Nakagawa Kamura, Yoshikazu Ishii, Kazuhiro Tateda   +4 more
openalex   +1 more source

Irradiated Tumor Cell‐Derived Microparticles Activate Systemic Anti‐Tumor Immunity via the STING/NLRP3/GSDMD Axis in Neutrophils

Advanced Science, EarlyView.
Radiotherapy induces tumor cells to release microparticles (RT‐MPs) into the circulation. The mitochondrial DNA carried by these RT‐MPs activates the STING/NLRP3/GSDMD axis in splenic neutrophils, triggering IL‐1β secretion. This, in turn, enhances dendritic cell function and facilitates the formation of cytotoxic T lymphocytes, thereby promoting ...
Yan Hu, Jiacheng Wang, Mengjie Che, Zheng Yang, Jingshu Meng, Xiao Yang, Yue Deng, Zhiyuan Zhou, Yijun Wang, Wenwen Wei, Zhanjie Zhang, Bian Wu, You Qin, Kunyu Yang, Honglin Jin, Fang Huang, Yajie Sun, Lu Wen, Chao Wan   +18 more
wiley   +1 more source

Novel rabies vaccine candidates development based on pseudotyped lentiviral vectors with rabies virus glycoprotein. [PDF]

PLoS Negl Trop Dis
Shuai L, Xu M, Pei N, Zhu C, Belghait M, Hu Z, Li J, Li H, Mao Y, Du H.   +9 more
europepmc   +1 more source

Lentivirus-mediated PHLDA2 overexpression inhibits trophoblast proliferation, migration and invasion, and induces apoptosis

, 2016
Feng Jin, Chong Qiao, Nannan Luan, Hui Li   +3 more
openalex   +2 more sources

Lentivirus Particles

As a leader in lentiviral technology, Creative Biogene has developed a comprehensive library of human, mouse, and rat genes cloned into lentiviral vectors or ready-to-use lentivirus, which can be used to manipulate the expression of your gene of interest within a wide range of host cells.
openaire   +1 more source

Autocrine Netrin‐1 Signaling in Hepatic Stellate Cells Drives Liver Fibrosis and Diet‐Induced Metabolic Dysfunction‐Associated Steatohepatitis in Mice

Advanced Science, EarlyView.
Netrin‐1 expression is upregulated in hepatic stellate cells (HSCs) during metabolic dysfunction–associated steatohepatitis and injury‐mediated liver fibrosis. Secreted Netrin‐1 establishes an autocrine positive feedback loop by binding to UNC5B receptors on HSCs.
Jiahui Zhao, Yajie Peng, Hongyan Lei, Tianyi Wang, Huajuan Wang, Bo Wang, Jin Li, Xiaoying Li, Xuelian Xiong   +8 more
wiley   +1 more source

Targeted demethylation of the BRD7 promoter based on CRISPR/dCas9 system inhibits the malignant progression of nasopharyngeal carcinoma. [PDF]

Clin Transl Med
Wei J, Duan Y, Xue C, Zheng L, Wei Q, Wu Z, Xin H, Zeng T, Deng H, Fan S, Xiong W, Zeng Z, Li M, Zhou M.   +13 more
europepmc   +1 more source

Generation of a molecular clone of an attenuated lentivirus, a first step in understanding cytopathogenicity and virulence

, 2015
Laure Blatti-Cardinaux, G. Pisoni, Michael Stoffel, Reto Zanoni, Marie-Luise Zahno, Giuseppe Bertoni   +5 more
openalex   +1 more source