Results 261 to 270 of about 199,900 (336)

754. Repeat Administration of Sendai Virus-F/HN Pseudotyped Lentivirus Vector to the Respiratory Epithelium Is Feasible

, 2008

openalex   +1 more source

Puerarin Targets MIC19 to Suppress Mitochondrial Metabolism of Tumor‐Infiltrating Tregs and Enhance Anti‐tumor Immunity

Advanced Science, EarlyView.
Puerarin targets mitochondrial MIC19 in tumor‐infiltrating Tregs, impairing their immunosuppressive function and enhancing antitumor immunity. This study uncovers the metabolic dependency of tumor‐infiltrating Tregs and highlights a potential metabolic‐targeted immunotherapeutic strategy for liver cancer. Abstract Regulatory T cells (Tregs) are pivotal
Yu Li, Ziyan Song, Jianjun Ding, Yiheng Zhou, Tianning Huang, Qufei Qian, Miao Yu, Wenzhao Chen, Jiazheng Liu, Ling Lu, Qiuyang Chen   +10 more
wiley   +1 more source

EIF4A3 Promotes Muscle Atrophy and Aging by Inhibiting the FAK Pathway Through NEDD9 mRNA Destabilization. [PDF]

J Cachexia Sarcopenia Muscle
Li Q, Yin X, Wan W, Zhou Y, Wang S, Yan Y, Chen J, Ren X, Gao J, Chen Y, Zhang Y, Cui C, Chatterjee E, Li G, Wu M, Zhang Y, Lu D, Yang T, Zheng Y, Li J.   +19 more
europepmc   +1 more source

Preclinical efficacy of a modified gamma-globin lentivirus gene therapy in Berkeley sickle cell anemia mice and human xenograft models

Archana Shrestha, Devin M. Pillis, Sydney Felker, Mengna Chi, Kimberly Wagner, Oluwabukola T. Gbotosho, Joseph Sieling, Mohammad Shadid, Punam Malik   +8 more
openalex   +1 more source

Establishment of an immortalized cell line derived from the prairie vole via lentivirus-mediated transduction of mutant cyclin-dependent kinase 4, cyclin D, and telomerase reverse transcriptase

, 2015
Masafumi Katayama, Tohru Kiyono, Kengo Horie, Takashi Hirayama, Takahiro Eitsuka, Kengo Kuroda, Kenichiro Donai, Shizu Hidema, Katsuhiko Nishimori, Tomokazu Fukuda   +9 more
openalex   +1 more source

Hepatocyte Mettl3 Deficiency Drives Primary Sclerosing Cholangitis and Liver Fibrosis via Cholangiocyte‐Macrophage Crosstalk

Advanced Science, EarlyView.
Schematic illustration demonstrating that hepatic Mettl3 depletion significantly elevates the secretion of Mif and Csf1. This elevation facilitates Trem2+ macrophage infiltration and triggers cholangiocyte remodeling through the Spp1‐Cd44 interaction, resulting in spontaneous PSC development in vivo.
Wenting Pan, Yuting Yong, Yuanshuai Li, Gaona Shi, Min Zhang, Lingfei Wan, Yue Zhao, Wenling Zhan, Yanli Lin, Qiaozhen Qin, Xupeng Chen, Yanli Ni, Haixu Chen, Wenzai Shi, Xiaomeng Guo, Juan Chen, Shuchen Liu, Youliang Wang, Bing Liu, Xinlong Yan   +19 more
wiley   +1 more source

Promotion of human choroidal melanoma cell metastases by FOXP3 <i>via</i> Wnt5a/CaMKII signaling pathway. [PDF]

Int J Ophthalmol
Yuan YY, Liu YC, Zhang Q, Gao XD, Zhu YZ, Cheng K, Zhao H, Fu WW, Lei K, Sui AH, Luo WJ.   +10 more
europepmc   +1 more source

Bovine Lentivirus Group [PDF]

, 2020
openaire   +1 more source

ARL5B Drives Esophageal Squamous Cell Carcinoma Progression via ROCK1–SREBP1‐Mediated Lipid Metabolic Reprogramming

Advanced Science, EarlyView.
Esophageal squamous cell carcinoma urgently requires new therapeutic strategies. Adenosine diphosphate‐ribosylation factor‐like protein 5B (ARL5B) is identified as a novel oncogene that remodels fatty acid metabolism through the ras homologous‐associated coiled‐coil containing protein kinase 1 (ROCK1)–sterol regulatory element‐binding protein 1 (SREBP1)
Xinyue Ma, Yanfei Sun, Hongyuan Mao, Chenhan Huang, Zerun Li, Tianzi Wang, Dizhi Jiang, Xinyu Zhang, Zhenyu Yuan, Zhihui Zhang, Bo Cheng, Ruiqing Wang, Yufeng Cheng   +12 more
wiley   +1 more source

Knockdown of the snoRNA-Jouvence Blocks the Proliferation and Leads to the Death of Human Primary Glioblastoma Cells. [PDF]

Noncoding RNA
Jaque-Cabrera L, Buggiani J, Bignon J, Daira P, Bernoud-Hubac N, Martin JR.   +5 more
europepmc   +1 more source