Results 271 to 280 of about 169,744 (339)

EFTUD2 Regulates Cortical Morphogenesis via Modulation of Caspase‐3 and Aifm1 Splicing Pathways

Advanced Science, EarlyView.
EFTUD2, a spliceosomal GTPase linked to MFDM, regulates cortical development through apoptotic control. Conditional Eftud2 knockout in murine neural stem cells induces microcephaly and cortical disorganization, while pathogenic variants drive neuronal loss.
Liping Chen, Ying Li, Yan Yu, Mingze Cai, Hao Li, Minghe Huang, Guochao Yang, Jiageng Guo, Huailin Wang, Zhihong Song, Wei Shen, Huihui Jiang, Haitao Wu   +12 more
wiley   +1 more source

Neuroprotective effect of riboflavin kinase on cerebral ischemia injury in rats. [PDF]

Mol Med
Zou Y, Ruan M, Feng X, Liu F, Liu W, Chen S, Chu Z.   +6 more
europepmc   +1 more source

In Vivo Impairment of Neutrophil Recruitment during Lentivirus Infection

, 2003
Paul Kubes, Bryan Heit, Guido van Marle, James B. Johnston, Derrice Knight, Adil I. Khan, Christopher Power   +6 more
openalex   +1 more source

PIP5K1A Suppresses Ferroptosis and Induces Sorafenib Resistance by Stabilizing NRF2 in Hepatocellular Carcinoma

Advanced Science, EarlyView.
Inducing ferroptosis is a promising strategy for combating tumor resistance. Upregulated PIP5K1A competes with NRF2 for KEAP1 binding, which decreases the ubiquitination degradation of NRF2 and promotes its nuclear translocation, thereby suppressing ferroptosis, and ultimately driving hepatocellular carcinoma (HCC) tumorigeneses and sorafenib ...
Mengzhou Guo, Sinuo Chen, Jialei Sun, Ruchen Xu, Zhuoran Qi, Jie Li, Lianer Zhou, Yuan Fang, Tianshu Liu, Jinglin Xia   +9 more
wiley   +1 more source

The Gene Expression Profile of Milk Somatic Cells of Small Ruminant Lentivirus-Seropositive and -Seronegative Dairy Goats (<i>Capra hircus</i>) During Their First Lactation. [PDF]

Viruses
Pławińska-Czarnak J, Majewska A, Zarzyńska JM, Kaba J, Bagnicka E.   +4 more
europepmc   +1 more source

Nasal Delivery of Engineered Exosomes via a Thermo‐Sensitive Hydrogel Depot Reprograms Glial Cells for Spinal Cord Repair

Advanced Science, EarlyView.
Engineered macrophage‐derived exosomes overexpressing GNA12 and GNA13 reprogram glial cells to promote neuroprotection and neural regeneration following SCI. A chitosan‐based thermosensitive hydrogel enables sustained intranasal exosome delivery, bypassing systemic barriers and enhancing therapeutic efficacy.
Yangyang Wang, Jingsong Liu, Pengfei Li, Zhibin Peng, Yubo Zhang, Yishu Liu, Mi Li, Xuqiang Gong, Daqian Liu, Enze Xu, Hongbo Yang, Yuanliang Sun, Yan Xu, Yansong Wang   +13 more
wiley   +1 more source

FKBP5 promotes osteogenic differentiation of mesenchymal stem cells through type-I interferon pathway Inhibition. [PDF]

Cell Mol Life Sci
Tang J, Li M, Chen Y, Liang Y, Yan W, Ning Q, Deng H, Liu H, Li Y, Huang L.   +9 more
europepmc   +1 more source

Long-term transgene expression by administration of a lentivirus-based vector to the fetal circulation of immuno-competent mice

, 2003
Simon N. Waddington, Kyriacos Mitrophanous, Fiona M. Ellard, Suzanne M. K. Buckley, Megha Nivsarkar, Lorraine Lawrence, H. Terence Cook, Faisal A. Al-Allaf, Brian Bigger, Susan M. Kingsman, Charles Coutelle, Michael Themis   +11 more
openalex   +1 more source

Lysosomal Cathepsin S Escape Facilitates Near Infrared Light‐Triggered Pyroptosis Via an Antibody‐Indocyanine Green Conjugate

Advanced Science, EarlyView.
ICAM1 antibody‐bound ICG triggers tumor‐specific, caspase‐1‐independent pyroptosis via CTSS‐mediated GSDMD cleavage, activates antitumor immunity, and synergizes with anti–PD‐1 therapy, offering a non‐apoptotic strategy to overcome resistance in cancer treatment.
Fan Chen, Xue‐Fei Tian, Teng Yang, Yu‐Jie Dai, Da‐Yuan Chen, Hong‐Bo Chen, Takaya Shimura, Xin‐Fang Li, Chu‐Lin Sha, Qing Ji, Jun Cao, Mei‐Yu Fang, Jin‐Biao Shang, Jian‐Min Fang, Ye Lu, Wei‐Hui Zheng, Peng Guo, Wei‐Hong Tan   +17 more
wiley   +1 more source

Human immunodeficiency virus type 1 Vif supports efficient primate lentivirus replication in rhesus monkey cells

, 2003
Sujata Kar, Phoebe Cummings, Louis Alexander   +2 more
openalex   +1 more source