Results 91 to 100 of about 2,445,354 (228)

LEOPARD syndrome and hypertrophic obstructive cardiomyopathy: a case report

The Turkish Journal of Pediatrics, 2004
The LEOPARD syndrome is a rare, autosomal dominant multisystemic disorder characterized by lentiginosis, ocular hypertelorism, abnormal genitalia, growth retardation, sensorineural deafness, and cardiac and electrocardiographic abnormalities ...
Ergun Cetinkaya, Nazlihan Günal, Nilgün Sönmez, Zehra Aycan, Sadi Vidinlisan, Oz Kahramanyol, Ilhan Paşaoğlu   +6 more
doaj  

Everolimus therapy in an infant with Noonan syndrome with multiple lentigines

Annals of Pediatric Cardiology
RASopathies are the most common underlying etiology in infants with hypertrophic cardiomyopathy. An improved understanding of the downstream molecular mechanisms of the disease has enabled us to target therapy for genetic abnormalities in human cancers ...
Mani Ram Krishna, Usha Nandhini Sennaiyan   +1 more
doaj   +1 more source

Roadless Areas in China: Dynamic Patterns and Conservation Implications

Earth's Future, Volume 13, Issue 12, December 2025.
Abstract Expanding public transportation and conserving biodiversity are two major components of the United Nations Sustainable Development Goals. However, these objectives often conflict, as habitat loss and fragmentation caused by transportation networks and subsequent development are regarded as significant threats to biodiversity.
Xinyue Fan, Weihua Xu, Mei Han, Li An, Jingjing Zhang, Zhiyun Ouyang   +5 more
wiley   +1 more source

AN ANALYSIS ON MALCOLM RIVER’S DISSOCIATIVE IDENTITY DISORDER IN IDENTITY MOVIE DIRECTED BY JAMES MANGOLD [PDF]

, 2017
This project aims to analyze the character Malcolm River in Identity movie. The result of analyzing the figures Malcolm Riversis that he suffered multiple personality syndrome or now known as Dissociative Identity Disorder. Malcolm was abused, neglected,
Wibowo, Abdul RohimIndra
core   +1 more source

Wildlife Trade and Human Health in Lao PDR: An Assessment of the Zoonotic Disease Risk in Markets. [PDF]

, 2016
Although the majority of emerging infectious diseases can be linked to wildlife sources, most pathogen spillover events to people could likely be avoided if transmission was better understood and practices adjusted to mitigate risk.
Douangngeun, Bounlom, Fine, Amanda E, Gilbert, Martin, Greatorex, Zoe F, Hansel, Troy, Joly, Damien O, Karesh, William B, Keatts, Lucy, Khammavong, Kongsy, Mazet, Jonna AK, O'Rourke, Kathleen, Olson, Sarah H, Silithammavong, Soubanh, Singhalath, Sinpakone, Theppangna, Watthana, Weisman, Wendy, Zimicki, Susan   +16 more
core   +2 more sources

Individual variation in animal communication: from species averages to unique voices

Biological Reviews, Volume 100, Issue 6, Page 2625-2640, December 2025.
ABSTRACT The comparative study of communicative behaviour in non‐human animals, especially primates, has yielded crucial insights into the evolution of human language. This research, mostly focused on the species and population level, has improved our understanding of the various socio‐ecological factors that shape communication systems.
Angèle Lombrey, Marlen Fröhlich
wiley   +1 more source

That's So Last Season: Unraveling the Genomic Consequences of Fur Farming in Arctic Foxes (Vulpes lagopus)

Molecular Ecology, Volume 34, Issue 24, December 2025.
ABSTRACT Humans have relied on animal fur for centuries, yet fur farming only began recently during the mid‐19th Century. Little is known about this incipient domestication or the genomic processes involved. Domestication may involve founder effects, population bottlenecks and low population size, which, when combined with intense artificial selection,
Christopher A. Cockerill, J. Camilo Chacón‐Duque, Nora Bergfeldt, Johanna von Seth, Gabriella Björklund, Malin Hasselgren, Johan Wallén, Anders Angerbjörn, Eva Fuglei, Ester Rut Unnsteinsdottir, Paula White, Gustaf Samelius, Ray Alisauskas, Dominique Berteaux, Øystein Flagstad, Arild Landa, Nina E. Eide, Remi‐André Olsen, Ignas Bunikis, Snæbjörn Pálsson, Kristinn Pétur Magnússon, Love Dalén, Karin Norén   +22 more
wiley   +1 more source

The Transition from Stem Cell to Progenitor Spermatogonia and Male Fertility Requires the SHP2 Protein Tyrosine Phosphatase [PDF]

, 2014
SHP2 is a widely expressed protein tyrosine phosphatase required for signal transduction from multiple cell surface receptors. Gain and loss of function SHP2 mutations in humans are known to cause Noonan and LEOPARD syndromes, respectively, that are ...
Feng, Gen‐sheng, King, Philip D., Lapinski, Philip E., Orwig, Kyle E., Phillips, Bart T., Puri, Pawan, Rajkovic, Aleksandar, Suzuki, Hitomi, Walker, William H.   +8 more
core   +1 more source

Mechanisms and Pathophysiological Significance of Insulin Resistance in Offspring With Intrauterine Growth Restriction Mediated by Hepatic GR/miR‐1224 Programming

Advanced Science, Volume 12, Issue 44, November 27, 2025.
This work found that early‐stage insulin sensitization but late‐stage insulin resistance in prenatal caffeine exposure (PCE)‐ induced intrauterine growth restriction (IUGR) offspring may be related to the hepatic AGEs accumulation via intrauterine GR/miR‐1224 programming by glucocorticoids.
Yongguo Dai, Xiaoling Guo, Pengxia Yu, Dingmei Zhang, Hao Kou, Hui Wang   +5 more
wiley   +1 more source

The Once and Future World: Nature As It Was, As It Is, As It Could Be by J.B. MacKinnon [PDF]

, 2014
Review of The Once and Future World: Nature As It Was, As It Is, As It Could Be by J.B ...
Banting, Pamela
core   +1 more source