Cryptosporidium varanii Infection in Captive Leopard Gecko (Eublepharis macularius) and Its Association with Wasting Syndrome in Thailand [PDF]
AnimalsCryptosporidiosis is a globally important protozoan disease that causes severe gastrointestinal illness in immunocompromised humans and animals and has been associated with chronic wasting and death in reptiles.
Panasaya Nipithakul +5 more
doaj +3 more sources
mTOR pathway in human cardiac hypertrophy caused by LEOPARD syndrome: a different role compared with animal models? [PDF]
Orphanet Journal of Rare Diseases, 2019 Background Animal studies suggested that blocking the activation of the mammalian target of rapamycin (mTOR) pathway might be effective to treat cardiac hypertrophy in LEOPARD syndrome (LS) caused by PTPN11 mutations.
Hao Cui +11 more
doaj +3 more sources
LEOPARD syndrome with PTPN11 gene mutation in monozygotic twins: A case description and literature review [PDF]
ESC Heart FailureYingwen Zhou +3 more
doaj +3 more sources
Kardiologiia, 2020 LEOPARD syndrome with multiple lentigines (cardiomyopathic lentiginosis) is a rare, genetically predetermined disease with autosomal dominant inheritance. Prevalence of this syndrome is unknown. One of pathognomonic clinical manifestations of this syndrome is the presence of multiple lentiginous pigment spots all over the body.
S A, Gabrusenko +4 more
semanticscholar +5 more sources
Melanoma and LEOPARD Syndrome: Understanding the Role of PTPN11 Mutations in Melanomagenesis [PDF]
Acta Dermato-Venereologicais missing (Short communication)
Rodolfo David Palacios-Diaz +4 more
doaj +2 more sources
LEOPARD syndrome: You could be the first one to diagnose!
Journal of Indian Society of Pedodontics and Preventive Dentistry, 2015 Leopard syndrome is a rare genetic disease complex associated with multiple anomalies. The main anomalies are summarized in the acronym LEOPARD in which each letter corresponds to mnemonic for the major features of this disorder:multiple Lentigines, ECG ...
Pallavi Urs +3 more
doaj +2 more sources
Juvenile Patient with LEOPARD Syndrome: Clinical Profile of a Genetically Confirmed Case. [PDF]
Ann Dermatol, 2023 Wan P, Cheng Y, Chen Z, Chen J.
europepmc +2 more sources
Leopard syndrome without lentigenes: A rare presentation and literature review
Journal of Integrative Medicine and ResearchLeopard syndrome (LS) has presentations of lentigines, conduction abnormalities in the heart, hypertelorism of the eyes, stenosis of the pulmonary artery, cryptorchidism, mental retardation, and sensorineural deafness.
Nikhila Gannavarapu +5 more
doaj +2 more sources
Multimodality Imaging of LEOPARD Syndrome: Myocardial Hypertrophy With Diffuse Coronary Artery Dilation. [PDF]
JACC Case Rep, 2022 We describe the case of a 5-year-old girl with genetically confirmed LEOPARD syndrome (LS) who presented with multiple lentigines, ocular hypertelorism, retardation of growth, myocardial hypertrophy, and diffuse coronary artery dilatation.
Yang D, Wang Y, Lu M.
europepmc +2 more sources
Biventricular Hypertrophic Cardiomyopathy in a Child with LEOPARD Syndrome: a Case Report
Journal of Interdisciplinary Medicine, 2017 Background: LEOPARD syndrome is a complex dysmorphogenetic disorder of inconstant penetrance and various morphologic expressions. The syndrome is an autosomal dominant disease that features multiple lentigines, electrocardiographic changes, eye ...
Blesneac Cristina +5 more
doaj +2 more sources