Results 81 to 90 of about 2,445,354 (228)

Doença do Verme do Coração (Dirofilaria immitis) em gato-do-mato-pequeno (Leopardus tigrinus) no Brasil [PDF]

open access: yes, 2009
Heartworm disease is caused by the intravascular nematode Dirofilaria immitis, a pathogen of public health importance usually associated to domestic dogs and cats, and to a lesser extend to other mammal species.
CATÃO-DIAS, José Luiz   +5 more
core   +2 more sources

Programmable Hydrogels: Frontiers in Dynamic Closed‐Loop Systems, Biomimetic Synergy, and Clinical Translation

open access: yesAdvanced Science, Volume 12, Issue 47, December 18, 2025.
This review summarizes the design principles and key features of programmable hydrogels that respond to multiple stimuli. It then delves into the cutting‐edge mechanisms of self‐executing systems, highlighting their role as the cornerstone of next‐generation programmable hydrogels (NGPHs).
Guangli Xiang   +8 more
wiley   +1 more source

Generation of an induced pluripotent stem cell line (TRNDi003-A) from a Noonan syndrome with multiple lentigines (NSML) patient carrying a p.Q510P mutation in the PTPN11 gene

open access: yesStem Cell Research, 2019
Noonan syndrome with multiple lentigines (NSML), formerly known as LEOPARD Syndrome, is a rare autosomal dominant disorder. Approximately 90% of NSML cases are caused by missense mutations in the PTPN11 gene which encodes the protein tyrosine phosphatase
Rong Li   +10 more
doaj   +1 more source

Clinical Genetics in Britain: Origins and development [PDF]

open access: yes, 2010
Annotated and edited transcript of a Witness Seminar held on 23 September 2008. Introduction by Professor Sir John Bell, Uiversity of Oxford.First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2010.©The Trustee of the ...
Harper, PS, Reynolds, LA, Tansey, EM
core  

Patient and Disease-Specific Induced Pluripotent Stem Cells for Discovery of Personalized Cardiovascular Drugs and Therapeutics. [PDF]

open access: yes, 2020
Human induced pluripotent stem cells (iPSCs) have emerged as an effective platform for regenerative therapy, disease modeling, and drug discovery.
Chandy, Mark   +2 more
core  

Ten years of the horse reference genome: insights into equine biology, domestication and population dynamics in the post-genome era. [PDF]

open access: yes, 2019
The horse reference genome from the Thoroughbred mare Twilight has been available for a decade and, together with advances in genomics technologies, has led to unparalleled developments in equine genomics.
Bellone, R   +3 more
core   +2 more sources

Physiological Differences Underlying Divergent Hypoxia Responses and Altitude Adaptations in Humans, Rats and Mice

open access: yesComprehensive Physiology, Volume 15, Issue 6, December 2025.
Despite many physiological similarities, mice, rats and humans respond remarkably differently to hypoxia. In line with their high‐altitude phylogeographic history, mice are physiologically well equipped to deal better with high‐altitude hypoxia than humans, while the low‐land origin of rats may be associated with a particularly high vulnerability to ...
Johannes Burtscher   +5 more
wiley   +1 more source

Noonan syndrome – a new survey

open access: yesArchives of Medical Science, 2016
Noonan syndrome (NS) is an autosomal dominant disorder with vast heterogeneity in clinical and genetic features. Various symptoms have been reported for this abnormality such as short stature, unusual facial characteristics, congenital heart ...
Alireza Tafazoli   +3 more
doaj   +1 more source

Clinically aggressive central giant cell granulomas in two patients with neurofibromatosis 1 [PDF]

open access: yes, 2006
Background Neurofibromatosis 1 (NF1) is an autosomal dominantly inherited disorder caused by a spectrum of mutations affecting the Nf1 gene. Affected patients develop benign and malignant tumors at an increased frequency.
Edwards, Paul C.   +5 more
core   +1 more source

Megafaunal Rodents: Behaviour and Ecological Roles of Southeast Asian Forest Porcupines

open access: yesEcology and Evolution, Volume 15, Issue 12, December 2025.
Southeast Asian porcupines (Malayan porcupine, Hystrix brachyura; brush‐tailed porcupine, Atherurus macrourus) performed at least four important ecological roles in a Malaysian rainforest. Burrows of both species were used in several ways by at least 22 animal species, while the soil above was potentially good sites for seedling recruitment. Porcupines
Kim R. McConkey   +9 more
wiley   +1 more source

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