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Expression of Placental Leptin and Leptin Receptors in Preeclampsia
International Journal of Gynecological Pathology, 2004This study investigated the expression profile of placental leptin and leptin receptor isoforms in preeclampsia, using placental tissue from normal pregnancies that were matched in gestational age and birth weight as controls. A total of 29 cases of preeclampsia were studied by immunohistochemistry, including 16 severe and 13 mild preeclampsia cases ...
Li, RHW, Poon, SCS, Yu, MY, Wong, YF
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Soluble receptor inhibits leptin transport
Journal of Cellular Physiology, 2007AbstractEvidence both from mice and cultured cells suggests an important role of soluble leptin receptors in obesity and leptin signaling. However, the direct effects of soluble receptors on leptin uptake by cells are not clear. This study shows that soluble leptin receptors antagonize the permeation of leptin across the mouse blood‐brain barrier by ...
Hong, Tu +3 more
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Immunoassays for Leptin and Leptin Receptors
2006Availability of methods for accurate and reproducible quantification of lepth in various biological fluids in humans and in animals has greatly facilitated research leading to the understanding of its role in various physiological and pathophysiological conditions. Immunoassay techniques provide a simple and robust tool for measurement of biomolecules.
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Role of leptin and leptin receptors in hematological malignancies
Leukemia & Lymphoma, 2015Leptin is an adipose-derived cytokine that has an important role in bodyweight homeostasis and energy balance. There are a number of studies which have suggested that leptin and its receptors dysregulation play a critical role in the development of malignancies including hematological malignancies, mainly via activation of the JAK/STAT pathway which ...
Shahab, Uddin, Ramzi M, Mohammad
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Leptin, Leptin Receptors, and the Control of Body Weight
Nutrition Reviews, 2009The assimilation, storage, and disposition of nutrient energy constitute a complex homeostatic system central to the survival of both prokaryotic and eukaryotic organisms. In vertebrates, and especially among land dwelling mammalian species, the ability to store large quantities of energy-dense fuel in the form of adipose tissue triglyceride permits ...
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Current treatment and recent progress in gastric cancer
Ca-A Cancer Journal for Clinicians, 2021Smita S Joshi, Brian D Badgwell
exaly