Results 191 to 200 of about 5,255,382 (240)
Pharmacotherapy for Leptomeningeal Disease in Breast Cancer [PDF]
Cancer Treatment ReviewsClinical data supporting the best therapeutic approach in leptomeningeal disease (LMD; also known as leptomeningeal metastases or leptomeningeal carcinomatosis) are lacking.
Katarzyna J Jerzak +2 more
exaly +5 more sources
Olaparib Treatment for BRCA-Mutant Ovarian Cancer With Leptomeningeal Disease [PDF]
Gynecologic Oncology Reports, 2016 HIGHLIGHTS: Leptomeningeal disease occurs more commonly in BRCA-mutated ovarian cancer; A clinically significant dose of olaprib is able to penetrate the leptomeninges; Leptomeningeal metastases in a BRCA-mutated ovarian cancer responded to ...
Madeleine Bangham, Jonathan A Ledermann
exaly +1 more source
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Brain Metastases and Leptomeningeal Disease
Continuum, 2023Central nervous system (CNS) metastases include brain parenchymal, spinal cord, and leptomeningeal metastases. This article discusses the diagnostic and therapeutic advances of the last decade that have improved outcomes for patients with these CNS metastases.The diagnostic tools for CNS metastases, particularly leptomeningeal disease, have evolved ...
Priya, Kumthekar, Emilie, Le Rhun
openaire +2 more sources
2008
Abstract Leptomeningeal metastases are an important, yet relatively infrequent, complication of malignancy. Leptomeningeal metastases are found in 5 per cent of all patients with cancer, but are believed to be increasing in frequency, due to more successful treatment options for the underlying malignancy. Prolonged survival, coupled with
Vicki Jackson, Lida Nabati
openaire +2 more sources
Abstract Leptomeningeal metastases are an important, yet relatively infrequent, complication of malignancy. Leptomeningeal metastases are found in 5 per cent of all patients with cancer, but are believed to be increasing in frequency, due to more successful treatment options for the underlying malignancy. Prolonged survival, coupled with
Vicki Jackson, Lida Nabati
openaire +2 more sources
Neurosurgery Clinics of North America, 2011
Leptomeningeal metastasis (LMD) is a lethal complication caused by a variety of cancers, typically developing late in the disease course. It is associated with major neurologic disabilities and short survival. The incidence of LMD may increase because of longer survival of patients who have cancer, and because of the use of newer large-molecule ...
openaire +3 more sources
Leptomeningeal metastasis (LMD) is a lethal complication caused by a variety of cancers, typically developing late in the disease course. It is associated with major neurologic disabilities and short survival. The incidence of LMD may increase because of longer survival of patients who have cancer, and because of the use of newer large-molecule ...
openaire +3 more sources
Advances in the Diagnosis and Treatment of Leptomeningeal Disease
Current Neurology and Neuroscience Reports, 2022Leptomeningeal disease (LMD) is a rare, late complication of systemic cancer and is associated with significant neurological morbidity and high mortality. Here we provide an overview of this condition, summarizing key recent research findings and clinical practice trends in its diagnosis and treatment.
Akanksha Sharma +2 more
openaire +2 more sources
Castleman's disease of the leptomeninges
Journal of Neurosurgery, 1988✓ Castleman's disease is a rare, benign lymphoproliferative disorder that usually arises in lymph nodes, most commonly in the mediastinum. The authors report the clinical and pathological features of three patients with localized Castleman's disease of the leptomeninges. There were two women, aged 63 and 82 years, and one 25-year-old man.
G S, Severson +8 more
openaire +2 more sources
Leptomeningeal Hodgkin's Disease
Annals of Internal Medicine, 1980Excerpt To the editor: Although involvement of the meninges is a well-known complication of carcinoma and lymphoma, such involvement in Hodgkin's disease is not.
ROBERT O. DILLMAN +3 more
openaire +1 more source
Leptomeningeal disease in BRIP1-mutated pancreatic adenocarcinoma
BMJ Case Reports, 2022Leptomeningeal disease is rare in pancreatic cancer and prognosis remains poor. Mutation profiles are now directing therapy to improve survival. We describe a case of leptomeningeal and brain metastasis in BRCA1 interacting protein 1, or BRIP1-mutated pancreatic adenocarcinoma with progression through several lines of chemotherapy and immunotherapy.
Eunji Yim, Denise Leung
openaire +2 more sources