Results 31 to 40 of about 42,791 (225)

In vivo and in silico Virulence Analysis of Leptospira Species Isolated From Environments and Rodents in Leptospirosis Outbreak Areas in Malaysia

Frontiers in Microbiology, 2021
The zoonotic disease leptospirosis is caused by pathogenic species of the genus Leptospira. With the advancement of studies in leptospirosis, several new species are being reported.
Noraini Philip, Jaeyres Jani, Nurul Natasya Azhari, Zamberi Sekawi, Vasantha Kumari Neela   +4 more
doaj   +1 more source

Leptospira spp. Prevalence in Cats from Southern Italy with Evaluation of Risk Factors for Exposure and Clinical Findings in Infected Cats

Pathogens, 2022
Leptospirosis is a worldwide zoonotic disease, but feline leptospirosis is rarely reported. This study aimed at investigating Leptospira spp. prevalence in cats from southern Italy, evaluating risk factors, clinical findings and laboratory data ...
Giulia Donato, M. Masucci, K. Hartmann, M. Goris, A. Ahmed, J. Archer, A. Alibrandi, M. Pennisi   +7 more
semanticscholar   +1 more source

Leptospira enrichment culture followed by ONT metagenomic sequencing allows better detection of Leptospira presence and diversity in water and soil samples

bioRxiv, 2022
Background Leptospirosis, a life-threatening disease in humans and animals, is one of the most widespread global zoonosis. Contaminated soil and water are the major transmission sources in humans and animals.
Myranda Gorman, Ruijie Xu, D. Prakoso, L. C. Salvador, S. Rajeev   +4 more
semanticscholar   +1 more source

Analyzying the documented results by using microscopic agglutination test to examine sera from patients suspected of leptospirosis

Инфекция и иммунитет, 2022
Leptospirosis holds one of the leading places among zoonoses due to the breadth of distribution of natural and economic foci, as well as the severity of the clinical manifestation and mortality rate.
A. P. Samsonova, E. M. Petrov, O. V. Savelyeva, A. E. Ivanova, N. E. Sharapova   +4 more
doaj   +1 more source

Leptospira Seropositivity in Humans, Livestock and Wild Animals in a Semi-Arid Area of Tanzania

Pathogens, 2021
Background: Leptospirosis is among the major neglected zoonoses in developing countries. The prevalence of leptospirosis remains underestimated in many African countries because of limited diagnostic facilities.
G. Mgode, G. Mhamphi, A. Massawe, R. Machang'u   +3 more
semanticscholar   +1 more source

A live attenuated-vaccine model confers cross-protective immunity against different species of the Leptospira genus

eLife, 2021
Leptospirosis is the leading zoonotic disease in terms of morbidity and mortality worldwide. Effective prevention is urgently needed as the drivers of disease transmission continue to intensify.
Elsio A. Wunder, Haritha Adhikarla, Camila Hamond, Katharine A. Owers Bonner, Li Liang, Camila B. Rodrigues, V. Bisht, J. Nally, D. Alt, M. Reis, P. Diggle, P. Felgner, A. Ko   +12 more
semanticscholar   +1 more source

THE OUTER MEMBRANE OF PATHOGENIC REPRESENTATIVES OF THE LEPTOSPIRA GENIUS

Инфекция и иммунитет, 2014
. Pathogenic leptospires can infect wide spectrum of hosts and they can survive in the environment long time. The outer membrane is the cellular component participated in interaction of microorganisms and environment.
A. N. Vaganova
doaj   +1 more source

Leptospira interrogans biofilm formation in Rattus norvegicus (Norway rats) natural reservoirs

PLoS Neglected Tropical Diseases, 2021
Rattus norvegicus (Norway rat) is the main reservoir host of pathogenic Leptospira, the causative agent of leptospirosis, in urban environments. Pathogenic Leptospira forms biofilms in the environment, possibly contributing for bacterial survival and ...
Ana Amélia Nunes Santos, Priscyla dos Santos Ribeiro, Geórgia Virgínia da França, F. N. Souza, E. Ramos, C. Figueira, M. Reis, F. Costa, Paula Ristow   +8 more
semanticscholar   +1 more source

Genetic manipulation of pathogenic Leptospira: CRISPR interference (CRISPRi)-mediated gene silencing and rapid mutant recovery at 37 °C

Scientific Reports, 2021
Leptospirosis is a neglected, widespread zoonosis caused by pathogenic species of the genus Leptospira, and is responsible for 60,000 deaths per year. Pathogenic mechanisms of leptospirosis remain poorly understood mainly because targeted mutations or ...
L. G. Fernandes, R. L. Hornsby, A. L. Nascimento, J. Nally   +3 more
semanticscholar   +1 more source

A Review on Host-Leptospira Interactions: What We Know and Future Expectations

Frontiers in Cellular and Infection Microbiology, 2021
Leptospirosis is a widespread zoonosis caused by pathogenic Leptospira spp. It is considered a neglected infectious disease of human and veterinary concern.
B. B. Daroz, L. G. Fernandes, Maria F. Cavenague, L. T. Kochi, Felipe J. Passalia, M. B. Takahashi, Edson G. Nascimento Filho, A. F. Teixeira, A. L. Nascimento   +8 more
semanticscholar   +1 more source