Results 31 to 40 of about 14,189 (215)
Mouse Model for Sublethal Leptospira interrogans Infection [PDF]
ABSTRACT Although Leptospira can infect a wide range of mammalian species, most studies have been conducted in golden Syrian hamsters, a species particularly sensitive to acute disease. Chronic disease has been well characterized in the rat, one of the natural reservoir hosts.
Luciana, Richer +4 more
openaire +2 more sources
Risk factors for human acute leptospirosis in northern Tanzania [PDF]
Introduction: Leptospirosis is a major cause of febrile illness in Africa but little is known about risk factors for human infection. We conducted a cross-sectional study to investigate risk factors for acute leptospirosis and Leptospira ...
Allan, Kathryn J. +16 more
core +2 more sources
Unique organization of Leptospira interrogans rRNA genes [PDF]
We cloned Sau3AI fragments containing the rRNA genes for Leptospira interrogans serovar canicola strain Moulton in the BamHI site of lambda EMBL3 bacteriophage DNA. Physical maps of the fragments were constructed, and the locations of the rRNA genes were determined by Southern blot hybridization and S1 protection.
M, Fukunaga, I, Mifuchi
openaire +2 more sources
Leptospirosis is a neglected zoonotic disease with global importance caused by pathogenic Leptospira. Rodents are considered the most significant reservoirs for both human and animal infection.
Jian-Wei Shao +6 more
doaj +1 more source
Leptospira interrogans Binds to Cadherins
Leptospirosis, caused by pathogenic species of Leptospira, is the most widespread zoonosis and has emerged as a major public health problem worldwide. The adhesion of pathogenic Leptospira to host cells, and to extracellular matrix (ECM) components, is likely to be necessary for the ability of leptospires to penetrate, disseminate and persist in ...
Karen Evangelista +3 more
openaire +4 more sources
The purpose of this study was to report the first recovery and characterization of Leptospira interrogans (serogroup Australis) from urine of swine in Brazil. The isolate was studied by serogrouping, MLVA, PGFE, and partial sequencing of rrs and secY. It
Camila Hamond +6 more
doaj +1 more source
Leptospirosis is a worldwide zoonosis caused by the pathogenic Leptospira spp. Canine and human leptospirosis sometimes occur on Amami Oshima Island, located in the Nansei Archipelago, southwestern Japan; however, information on the causative Leptospira ...
So Shinya +3 more
doaj +1 more source
Glycolipoprotein Cytotoxin from Leptospira interrogans serovar copenhageni [PDF]
Lipopolysaccharide (LPS), glycolipoprotein (GLP) and lipid extract were prepared from Leptospira interrogans serovar copenhageni. GLP, lipid extract or purified fatty acids from lipid extract produced cytotoxic effects seen as cell enzyme leakage followed by cytotoxic death when tested in mouse fibroblast L929 cells in tissue culture. All extracts also
T, Vinh, B, Adler, S, Faine
openaire +2 more sources
Leptospira Interrogans induces fibrosis in the mouse kidney through Inos-dependent, TLR- and NLR-independent signaling pathways. [PDF]
BACKGROUND: Leptospira (L.) interrogans are bacteria responsible for a worldwide reemerging zoonosis. Rodents carry L. interrogans asymptomatically in their kidneys and excrete bacteria in the urine, contaminating the environment.
Martine Fanton d'Andon +8 more
doaj +1 more source
Advances and challenges in barcoding pathogenic and environmental Leptospira [PDF]
Leptospirosis is a zoonotic bacterial disease of global importance. A large spectrum of asymptomatic animal hosts can carry the infection and contribute to the burden of human disease.
Allan, Kathryn J. +2 more
core +4 more sources

