Results 131 to 140 of about 22,625 (246)

The multicellular environment of the re‐entrant circuit in post‐myocardial infarction ventricular tachycardia: Beyond fibrosis

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the temporal evolution of the post‐myocardial infarction substrate leading to ventricular tachycardia. Acute ischaemic injury initiates metabolic and electrophysiological disruption, followed by progressive inflammatory, fibrotic and structural remodelling within the infarct border zone.
Mohammed Obeidat, Jaffar Al‐Sheikhli, Andrew M. Blanks, Joseph Mayer, Nicolas Lellouche, Tarvinder Dhanjal, Christopher O'Shea   +6 more
wiley   +1 more source

Dexamethasone Versus Placebo in Comatose Survivors of Out‐of‐Hospital Cardiac Arrest: Study Protocol for a Multicenter Randomized Comparison Within the Danish Out‐of‐Hospital Cardiac Arrest Trial (DANOHCA)

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 7, August 2026.
ABSTRACT Background The inflammatory response to whole‐body ischemia, as seen in comatose survivors after out‐of‐hospital cardiac arrest (OHCA), is associated with increased morbidity and mortality. Early high‐dose dexamethasone may dampen the inflammatory response, which may diminish secondary brain damage and other organ injury and decrease mortality.
Jo B. Andreasen, Anders Morten Grejs, Simon Mölström, Lars P. K. Andersen, Sören Möller, Steffen Christensen, Henrik Schmidt, Jacob E. Møller, Martin A. S. Meyer, Jesper Kjærgaard, Alexander W. Erbs, Bodil S. Rasmussen, Christian Hassager   +12 more
wiley   +1 more source

Safety and efficacy of intravenous tPA after successful thrombectomy for large vessel occlusion: a retrospective study. [PDF]

Front Neurol
Kotsugi M, Okamoto T, Hayami H, Nakase K, Morisaki Y, Yokoyama S, Matsuda R, Yamada S, Nakagawa I.   +8 more
europepmc   +1 more source

Specific Deletion of Interleukin‐1 Beta in Microglia Improves Acute Outcome and Modulates Neurogenesis After Ischemic Stroke

Glia, Volume 74, Issue 7, July 2026.
Microglial IL‐1β deletion improves acute outcome and reduces neutrophil recruitment after experimental ischemic stroke. Microglial IL‐1β deletion increases neurogenesis in the subventricular zone after experimental ischemic stroke. ABSTRACT Interleukin‐1 (IL‐1) signaling is a major driver of post‐ischemic neuroinflammation, yet the cell‐ and isoform ...
Alba Grayston, Margarida Baptista, Kelly Wemyss, Ruby Taylor, Grace Cullen, Syeda S. Jafree, Nadim Luka, Joshua R. Cox, Joanne E. Konkel, David Brough, Stuart M. Allan, Emmanuel Pinteaux   +11 more
wiley   +1 more source

Peri-procedural recognition of a calcified cerebral embolus following mechanical thrombectomy: A case report. [PDF]

Radiol Case Rep
Dai M, Ogura T, Ohmori S.
europepmc   +1 more source

Curcumin Attenuates Aroclor 1254‐Induced Oxidative, Genotoxic, and Apoptotic Alterations in HepG2 Cells

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 7, July 2026.
In HepG2 cells, Aroclor 1254 induced oxidative stress, DNA damage, apoptosis, and mutagenicity; co‐treatment with curcumin restored antioxidant defenses (GSH/thiols; SOD, CAT, GPx, GR, TrxR), reduced ROS and comet/8‐OHdG readouts, and attenuated caspase activation, demonstrating curcumin's hepatoprotective and genoprotective modulation of PCB toxicity.
Pınar Erkekoğlu, Selinay Başak Erdemli Köse, Hülya Tezel Yalçın, Deniz Arca Çakır   +3 more
wiley   +1 more source

Temporal dynamics of diffusion kurtosis imaging parallels astroglial GFAP expression in a non-traumatic spinal cord injury animal model of ischemia-reperfusion. [PDF]

Front Neurol
Wang L, Li X, Wang L, Li D.
europepmc   +1 more source

Cuidado de enfermería al paciente en la reanimación cardio-cerebro pulmonar.

, 2018
En este artículo se explora los cuidados de enfermería en una reanimación cerebro-cardio- pulmonar (RCP) en los tres momentos. Objetivo: Realizar revisión documental sobre cuidados de enfermería a la persona antes, durante y después del paro cardio ...
Gómez López, Sandy Saraí, Castro Ramírez, Lilibeth, Ayala Tarazona, Wilmer Libardo, Álvarez Ramírez, Johanna Marcela, Marín González, Ivone Marcela   +4 more
core  

Ischemia–Reperfusion Injury: Molecular Mechanisms and Therapeutic Interventions

MedComm, Volume 7, Issue 7, July 2026.
Multiorgan ischemia–reperfusion injury begins with ischemia‐induced ATP depletion and ionic imbalance, followed by reperfusion‐triggered mitochondrial ROS/RNS bursts, regulated cell death, and DAMP release. Sterile inflammation converges on endothelial–immune–coagulation crosstalk, where NETs drive immunothrombosis, no‐reflow, and remote organ injury ...
Peng An, Yi An, Mengwei Chen, Longlong Wu, Rong Wang   +4 more
wiley   +1 more source

The role of fluvoxamine in the treatment of endotoxin‐induced acute heart injury

British Journal of Pharmacology, Volume 183, Issue 13, Page 3815-3828, July 2026.
Abstract Background and Purpose Cardiovascular diseases are among the most common health problems worldwide. Inflammation plays a critical role in the pathogenesis of various heart diseases. Lipopolysaccharides (LPS) trigger inflammatory mechanisms, leading to an inflammatory response.
Ilter Ilhan, Halil Aşcı, Muhammet Yusuf Tepebasi, Nursel Hasseyid, Melih Arlıoğlu, Özlem Özmen   +5 more
wiley   +1 more source