Abstract The isoproterenol‐induced myocardial infarction model is a well‐established experimental approach for studying cardiac injury and testing potential protective treatments. By overstimulating beta‐adrenergic receptors, this model closely reproduces key features of human heart attacks, including oxidative damage, calcium imbalance, inflammatory ...
Bushra Imran +5 more
wiley +1 more source
Case Report: The aslanger pattern as an indicator of severe acute coronary syndrome. [PDF]
Chen YZ +5 more
europepmc +1 more source
LKB1–AMPK Signaling Pathway in Cardiovascular and Other Diseases
The LKB1–AMPK pathway has a central regulatory role in various diseases. Dysfunction of this pathway can lead to pathological processes in cardiovascular diseases (atrial fibrillation, myocardial infarction, myocardial hypertrophy, atherosclerosis), metabolic diseases (diabetes and kidney disease), neurodegenerative diseases (Alzheimer's disease ...
Zhuo Chen, Qin Yang, Guo‐Wei He
wiley +1 more source
Successful reperfusion for better outcomes in medium vessel occlusion: Penumbral salvage versus infarct volume reduction. [PDF]
He G +8 more
europepmc +1 more source
The NLRP3 Inflammasome: Mechanisms of Activation, Regulation, and Therapeutic Opportunities
Diverse diseases converge on NLRP3. We depict a discovery‐to‐clinic track: high‐throughput/phenotypic screens, structure‐guided design, and modality innovation (allosteric inhibitors, interface blockers, degraders) deliver third‐generation, disease‐tailored NLRP3 control.
Chan Zou +5 more
wiley +1 more source
Diagnostic challenges in acute coronary syndrome: reconciling the STEMI-NSTEMI and OMI-NOMI paradigms. [PDF]
Umit TB +6 more
europepmc +1 more source
Human Cyclophilins—An Emerging Class of Drug Targets
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova +3 more
wiley +1 more source
Pitfalls of Posterior Leads for Posterior Occlusion MI. [PDF]
Newmarch T, El-Baba M, McLaren JTT.
europepmc +1 more source
“CRITERIOS NO INVASIVOS DE REPERFUSIÓN CORONARIA, EN PACIENTES CON INFARTO AGUDO AL MIOCARDIO CON ELEVACIÓN DEL SEGMENTO ST,EN LA SALA DE CHOQUE DEL CENTRO MÉDICO LIC. ADOLFO LÓPEZ MATEOS” [PDF]
Campa Escobar, Jesús Alberto +1 more
core
RNA‐Binding Proteins and Ferroptosis in Cancer: Mechanism and Therapeutic Implications
Ferroptosis critically influences cancer cell fate and represents a promising therapeutic strategy. Emerging evidence identifies RNA‐binding proteins (RBPs) as key post‐transcriptional regulators of ferroptosis. The figure summarizes ferroptosis‐related RBPs across cancers: blue RBPs act as tumor suppressors by promoting ferroptosis, whereas red RBPs ...
Linlin Chang +6 more
wiley +1 more source

