MRI and clinical resolution of a suspected intracranial toxoplasma granuloma with medical treatment in a domestic short hair cat [PDF]
A two-year-old cat was presented with a left paradoxical vestibular syndrome. MRI of the brain revealed an extra-axial homogenously contrast enhancing mass in the region of the left caudal cerebellar peduncle.
Beltran, E, Crawford, A H, Drees, R
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Chronic white matter lesion activity predicts clinical progression in primary progressive multiple sclerosis. [PDF]
Chronic active and slowly expanding lesions with smouldering inflammation are neuropathological correlates of progressive multiple sclerosis pathology.
Arnold, Douglas L +10 more
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Analysis of lesion localisation at colonoscopy: outcomes from a multi-centre U.K. study [PDF]
Background: Colonoscopy is currently the gold standard for detection of colorectal lesions, but may be limited in anatomically localising lesions. This audit aimed to determine the accuracy of colonoscopy lesion localisation, any subsequent changes in
Anderson, John H. +22 more
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Morphologic Criteria of Lesion Activity in Neovascular Age-Related Macular Degeneration: A Consensus Article [PDF]
Intravitreal antivascular endothelial growth factor drugs represent the current standard of care for neovascular age-related macular degeneration (nAMD).
Elena Gusson +8 more
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Brain networks under attack : robustness properties and the impact of lesions [PDF]
A growing number of studies approach the brain as a complex network, the so-called ‘connectome’. Adopting this framework, we examine what types or extent of damage the brain can withstand—referred to as network ‘robustness’—and conversely, which kind of ...
Aerts, Hannelore +3 more
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Intrinsic up-regulation of 2-AG favors an area specific neuronal survival in different in vitro models of neuronal damage [PDF]
BACKGROUND: The endocannabinoid 2-arachidonoyl glycerol (2-AG) acts as a retrograde messenger and modulates synaptic signaling e. g. in the hippocampus. 2-AG also exerts neuroprotective effects under pathological situations.
Bechmann, Ingo Jürgen +8 more
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Exceptional aggressiveness of cerebral cavernous malformation disease associated with PDCD10 mutations. [PDF]
PurposeThe phenotypic manifestations of cerebral cavernous malformation disease caused by rare PDCD10 mutations have not been systematically examined, and a mechanistic link to Rho kinase-mediated hyperpermeability, a potential therapeutic target, has ...
Akers, Amy L +16 more
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Naming and recognition of six foot lesions of sheep using written and pictorial information: a study of 809 English sheep farmers [PDF]
In 2005, 3000 questionnaires were sent to a random sample of English sheep farmers from a list kept by the English Beef and Lamb Executive (EBLEX) to investigate whether farmers could correctly name six common foot lesions in sheep from a characteristic ...
Green, Laura E., Kaler, Jasmeet
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Diagnosis in vascular dementia, applying ‘Cochrane diagnosis rules’ to ‘dementia diagnostic tools’ [PDF]
In this issue of Clinical Science, Biesbroek and colleagues describe recent work on magnetic resonance imaging (MRI)-based cerebral lesion location and its association with cognitive decline.
McCleery, Jenny, Quinn, Terence J.
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Functional connectivity in relation to motor performance and recovery after stroke. [PDF]
Plasticity after stroke has traditionally been studied by observing changes only in the spatial distribution and laterality of focal brain activation during affected limb movement.
Nagarajan, Srikantan S +1 more
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