Results 1 to 10 of about 1,972,553 (236)

A novel cuproptosis-related gene signature for predicting prognosis in cervical cancer

open access: yesFrontiers in Genetics, 2022
Purpose: Cuproptosis, a form of copper-induced cell death, can be a promising therapeutic target for refractory cancers. Hence, we conducted this research to explore the association between cuproptosis and prognosis in cervical cancer (CC).Methods: For ...
Lei Lei, Liao Tan, Long Sui
doaj   +1 more source

RETRACTED: ECT2 Increases the stability of EGFR and Tumorigenicity by Inhibiting Grb2 Ubiquitination in Pancreatic Cancer

open access: yesFrontiers in Oncology, 2021
The poor prognosis of patients with pancreatic ductal adenocarcinoma (PDAC) is associated with the invasion and metastasis of tumor cells. Epithelial cell transforming 2 (ECT2) is a guanine nucleotide exchange factor (GEF) of the Rho family of GTPases ...
Junxiong Wang   +15 more
doaj   +1 more source

Over-the-scope clip-assisted endoscopic full-thickness resection has potential to treat complex nonampullary duodenal lesions: a single-center case series

open access: yesBMC Gastroenterology, 2021
Background and aims The duodenum is considered a challenging area for the endoscopic resection of lesions. This study aimed to evaluate the efficacy and safety of over-the-scope clip (OTSC)-assisted endoscopic full-thickness resection (EFTR) for complex ...
Yongqiu Wei   +4 more
doaj   +1 more source

Of networked lesions and lesioned networks

open access: yesBrain, 2022
This scientific commentary refers to ‘Post-stroke outcomes predicted from multivariate lesion-behaviour and lesion network mapping’ by Bowren et al. (https://doi.org/10.1093/brain/awac010).
Robert Gray, Parashkev Nachev
openaire   +3 more sources

KLF13 suppresses the proliferation and growth of colorectal cancer cells through transcriptionally inhibiting HMGCS1-mediated cholesterol biosynthesis

open access: yesCell & Bioscience, 2020
Background Colorectal cancer (CRC) is the fourth most deadly malignancy throughout the world. Extensive studies have shown that Krüppel-like factors (KLFs) play essential roles in cancer development.
Weilong Yao   +3 more
doaj   +1 more source

Both extracellular vesicles from helicobacter pylori-infected cells and helicobacter pylori outer membrane vesicles are involved in gastric/extragastric diseases

open access: yesEuropean Journal of Medical Research, 2023
Bacterial-derived extracellular vesicles (EVs) have emerged as crucial mediators in the cross-talk between hosts and pathogens, playing a significant role in infectious diseases and cancers. Among these pathogens, Helicobacter pylori (H.
Chengyao Wang   +7 more
doaj   +1 more source

Does Early Endoscopy Affect the Clinical Outcomes of Patients with Acute Nonvariceal Upper Gastrointestinal Bleeding? A Systematic Review and Meta-Analysis

open access: yesGut and Liver, 2023
Background/Aims: In patients with acute nonvariceal upper gastrointestinal bleeding (ANVUGIB), the optimal timing of endoscopy is still a matter of dispute.
Liyi Bai   +5 more
doaj   +1 more source

Impact of chromophores on colour appearance in a computational skin model [PDF]

open access: yes, 2020
Early diagnosis of skin cancer offers the patient more favorable treatment options. Color fidelity of skin images is a major concern for dermatologists as adoption of digital dermatoscopes is increasing rapidly. Accurate color depiction of the lesion and
Bakic, Predrag R.   +6 more
core   +4 more sources

Exosomal Sonic Hedgehog derived from cancer‐associated fibroblasts promotes proliferation and migration of esophageal squamous cell carcinoma

open access: yesCancer Medicine, 2020
Esophageal squamous cell carcinoma (ESCC) is one of the most common and aggressive malignancies in China. Cancer‐associated fibroblasts (CAFs) can actively communicate with and stimulate tumor cells, thereby contributing to the development and ...
Guiping Zhao   +6 more
doaj   +1 more source

Non-alcoholic fatty liver is associated with increased risk of irritable bowel syndrome: a prospective cohort study

open access: yesBMC Medicine, 2022
Background The relationship between non-alcoholic fatty liver degree as well as non-alcoholic fatty liver disease (NAFLD) and irritable bowel syndrome (IBS) remains poorly understood.
Shanshan Wu   +6 more
doaj   +1 more source

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