Results 31 to 40 of about 2,066,107 (321)

Cellular and Extracellular Components in Tumor Microenvironment and Their Application in Early Diagnosis of Cancers

open access: yesAnalytical Cellular Pathology, 2020
Tumors are surrounded by complex environmental components, including blood and lymph vessels, fibroblasts, endothelial cells, immune cells, cytokines, extracellular vesicles, and extracellular matrix.
Rui Wei   +4 more
doaj   +1 more source

Vitamin D3 Inhibits Helicobacter pylori Infection by Activating the VitD3/VDR-CAMP Pathway in Mice

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
Helicobacter pylori (H. pylori) infection is closely associated with the occurrence and development of gastric diseases. Therefore, eliminating H. pylori infection should help to prevent gastric diseases.
Anni Zhou   +9 more
doaj   +1 more source

A Comparative Trial of Single Dose Chemotherapy in Paucibacillary Leprosy Patients with Two to Three Skin Lesions. [PDF]

open access: yes, 2001
A multicentric double-blind, controlled, clinical trial was carried out to compare the efficacy of a combination of rifampicin 600 mg plus ofloxacin 400 mg plus minocycline 100 mg (ROM) administered as single dose with that of standard WHO/MDT/PB six ...
2-3 Lesion Multicentre Trial Group, --
core  

Granulocyte-colony stimulating factor in experimental stroke and its effects on infarct size and functional outcome: a systematic review [PDF]

open access: yes, 2009
Background Granulocyte-colony stimulating factor (G-CSF) shows promise as a treatment for stroke. This systematic review assesses G-CSF in experimental ischaemic stroke.
Alvarez-Dolado   +55 more
core   +2 more sources

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Long-term risk of irritable bowel syndrome associated with MASLD, MASLD type and different cardiometabolic risk factors: a large-scale prospective cohort study

open access: yesBMC Gastroenterology
Background Despite the increased irritable bowel syndrome (IBS) risk associated with hepatic steatosis demonstrated in prior evidence, it is still unclear whether the newly coined metabolic dysfunction-associated steatotic liver disease (MASLD), could in
Yesheng Zhou   +7 more
doaj   +1 more source

FAM175B promotes apoptosis by inhibiting ATF4 ubiquitination in esophageal squamous cell carcinoma

open access: yesMolecular Oncology, 2019
FAM175B is a reported regulator of p53 and suppresses tumorigenesis in numerous types of cancer, but very little is known about its function in esophageal squamous cell carcinomas (ESCCs), almost 70% of which exhibit mutations in p53.
Yu Zhao   +9 more
doaj   +1 more source

Deep Lesion Graphs in the Wild: Relationship Learning and Organization of Significant Radiology Image Findings in a Diverse Large-scale Lesion Database

open access: yes, 2018
Radiologists in their daily work routinely find and annotate significant abnormalities on a large number of radiology images. Such abnormalities, or lesions, have collected over years and stored in hospitals' picture archiving and communication systems ...
A Esteva   +23 more
core   +1 more source

Naming and recognition of six foot lesions of sheep using written and pictorial information: a study of 809 English sheep farmers [PDF]

open access: yes, 2008
In 2005, 3000 questionnaires were sent to a random sample of English sheep farmers from a list kept by the English Beef and Lamb Executive (EBLEX) to investigate whether farmers could correctly name six common foot lesions in sheep from a characteristic ...
Green, Laura E., Kaler, Jasmeet
core   +2 more sources

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

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