Results 41 to 50 of about 3,826,952 (368)

Non-Thermal Plasma Jet-Treated Medium Induces Selective Cytotoxicity against Mycobacterium tuberculosis-Infected Macrophages

Biomedicines, 2022
Plasma-treated media (PTM) serve as an adjuvant therapy to postoperatively remove residual cancerous lesions. We speculated that PTM could selectively kill cells infected with Mycobacterium tuberculosis (Mtb) and remove postoperative residual tuberculous
Chae Bok Lee, Kang In Lee, Young Jae Kim, In Taek Jang, Sintayehu Kebede Gurmessa, Eun Ha Choi, Nagendra Kumar Kaushik, Hwa-Jung Kim   +7 more
doaj   +1 more source

Multimodal skin lesion classification using deep learning

Experimental Dermatology, 2018
While convolutional neural networks (CNNs) have successfully been applied for skin lesion classification, previous studies have generally considered only a single clinical/macroscopic image and output a binary decision.
J. Yap, William Yolland, P. Tschandl
semanticscholar   +1 more source

Dysflective cones: Visual function and cone reflectivity in long-term follow-up of acute bilateral foveolitis. [PDF]

, 2017
PURPOSE:Confocal adaptive optics scanning laser ophthalmoscope (AOSLO) images provide a sensitive measure of cone structure. However, the relationship between structural findings of diminished cone reflectivity and visual function is unclear.
Cunningham, Emmett T, Duncan, Jacque L, Foote, Katharina G, Gorin, Michael B, Lujan, Brandon J, Qin, Jia, Ratnam, Kavitha, Roorda, Austin, Tu, Joanna H, Tuten, William S   +9 more
core   +1 more source

FAM175B promotes apoptosis by inhibiting ATF4 ubiquitination in esophageal squamous cell carcinoma

Molecular Oncology, 2019
FAM175B is a reported regulator of p53 and suppresses tumorigenesis in numerous types of cancer, but very little is known about its function in esophageal squamous cell carcinomas (ESCCs), almost 70% of which exhibit mutations in p53.
Yu Zhao, Yang Yu, Hengcun Li, Zheng Zhang, Shuilong Guo, Shengtao Zhu, Qingdong Guo, Peng Li, Li Min, Shutian Zhang   +9 more
doaj   +1 more source

Intracellular matrix Gla protein promotes tumor progression by activating JAK2/STAT5 signaling in gastric cancer

Molecular Oncology, 2020
Matrix Gla protein (MGP) has been widely reported as an extracellular matrix protein with abnormal expression in various types of cancer. However, the function of intracellular MGP in gastric cancer (GC) cells remains largely unknown.
Mizhu Wang, Lei Chen, Yu Chen, Rui Wei, Qingdong Guo, Shengquan Zhu, Shuilong Guo, Shengtao Zhu, Shutian Zhang, Li Min   +9 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

A Comparative Trial of Single Dose Chemotherapy in Paucibacillary Leprosy Patients with Two to Three Skin Lesions. [PDF]

, 2001
A multicentric double-blind, controlled, clinical trial was carried out to compare the efficacy of a combination of rifampicin 600 mg plus ofloxacin 400 mg plus minocycline 100 mg (ROM) administered as single dose with that of standard WHO/MDT/PB six ...
2-3 Lesion Multicentre Trial Group, --
core  

Long-term risk of irritable bowel syndrome associated with MASLD, MASLD type and different cardiometabolic risk factors: a large-scale prospective cohort study

BMC Gastroenterology
Background Despite the increased irritable bowel syndrome (IBS) risk associated with hepatic steatosis demonstrated in prior evidence, it is still unclear whether the newly coined metabolic dysfunction-associated steatotic liver disease (MASLD), could in
Yesheng Zhou, Zhirong Yang, Si Liu, Sian Xie, Qian Zhang, Shutian Zhang, Shengtao Zhu, Shanshan Wu   +7 more
doaj   +1 more source

Cellular and Extracellular Components in Tumor Microenvironment and Their Application in Early Diagnosis of Cancers

Analytical Cellular Pathology, 2020
Tumors are surrounded by complex environmental components, including blood and lymph vessels, fibroblasts, endothelial cells, immune cells, cytokines, extracellular vesicles, and extracellular matrix.
Rui Wei, Si Liu, Shutian Zhang, Li Min, Shengtao Zhu   +4 more
doaj   +1 more source

Advanced lesion symptom mapping analyses and implementation as BCBtoolkit

bioRxiv, 2017
Background Patients with brain lesions provide a unique opportunity to understand the functioning of the human mind. However, even when focal, brain lesions have local and remote effects that impact functionally and structurally connected circuits ...
Chris Foulon, L. Cerliani, S. Kinkingnéhun, Richard Levy, Charlotte Rosso, M. Urbanski, Emmanuelle Volle, M. Thiebaut de Schotten   +7 more
semanticscholar   +1 more source