Results 41 to 50 of about 1,781,133 (270)

Intraoperative Collection of Ascitic Fluid With Intra‐ or Postoperative Reinfusion in Ovarian Cancer: Safety and Feasibility of a Roller Pumping Method

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients with ovarian cancer often present with massive ascites, leading to significant protein loss during surgical procedures. Although cell‐free concentrated ascites reinfusion therapy (CART) is used in palliative settings to mitigate protein loss, its application in intraoperative settings remains unexplored.
Yutaka Yoneoka, Tsukuru Amano, Akimasa Takahashi, Mari Deguchi, Hiroyuki Yamanaka, Yuji Tanaka, Shunichiro Tsuji, Takashi Murakami   +7 more
wiley   +1 more source

Cellular and Extracellular Components in Tumor Microenvironment and Their Application in Early Diagnosis of Cancers

Analytical Cellular Pathology, 2020
Tumors are surrounded by complex environmental components, including blood and lymph vessels, fibroblasts, endothelial cells, immune cells, cytokines, extracellular vesicles, and extracellular matrix.
Rui Wei, Si Liu, Shutian Zhang, Li Min, Shengtao Zhu   +4 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Skin Lesions in Children: Evaluation of Clinicopathological Findings

Türk Patoloji Dergisi, 2023
Objective: Pediatric skin diseases may show various manifestations, occasionally affecting the patients quality of life. Histopathological examination may be required for the diagnosis.
Begum CALIM-GURBUZ, Burcin PEHLIVANOGLU, Tuce SOYLEMEZ-AKKURT, Ozan ERDEM, Anvar AHMEDOV   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Multi-omics Analysis of Gut Microbiota and Metabolites in Rats With Irritable Bowel Syndrome

Frontiers in Cellular and Infection Microbiology, 2019
Irritable bowel syndrome (IBS) is a common gastrointestinal dysfunctional disease. The pathophysiology of IBS is, however, largely unknown. This study aimed to determine whether evaluation of fecal metabolite and microbiota profiles may offer an ...
Si Liu, Chaozeng Si, Yang Yu, Guiping Zhao, Lei Chen, Yu Zhao, Zheng Zhang, Hengcun Li, Yang Chen, Li Min, Shutian Zhang, Shengtao Zhu   +11 more
doaj   +1 more source

Study Of The Special Features Of The Meniscal Tear

Central Asian Journal of Medical Sciences, 2023
Objectives: Arthroscopic meniscectomy is a treatment with good short-term results. To prevent the long-term adverse effects of meniscal tear injuries, it is necessary to study the unique features, such asthedemographic characteristics of the injury, the ...
Orgil Zorigtbaatar, Gonchigsuren Dagvasumberel, Naranbat Lkhagvasuren, Baatarjav Sosor   +3 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The Evidence for a Causal Link Between Disease and Damaging Behavior in Pigs

Frontiers in Veterinary Science, 2022
Damaging behaviors (DB) such as tail and ear biting are prevalent in pig production and reduce welfare and performance. Anecdotal reports suggest that health challenges increase the risk of tail-biting.
Laura A. Boyle, Sandra A. Edwards, J. Elizabeth Bolhuis, Françoise Pol, Manja Zupan Šemrov, Sabine Schütze, Janicke Nordgreen, Nadya Bozakova, Evangelia N. Sossidou, Anna Valros   +9 more
doaj   +1 more source