Results 61 to 70 of about 1,344,206 (319)

Entorhinal denervation induces homeostatic synaptic scaling of excitatory postsynapses of dentate granule cells in mouse organotypic slice cultures

, 2012
Denervation-induced changes in excitatory synaptic strength were studied following entorhinal deafferentation of hippocampal granule cells in mature (≥3 weeks old) mouse organotypic entorhino-hippocampal slice cultures.
Roeper, Jochen, Roeper Jochen, Winkels, Raphael, Denise Becker (179935), Thomas Deller, Thomas Deller (179947), Denise Becker, Jedlička, Peter, Becker Denise, Jochen Roeper, Jedlicka Peter, Winkels Raphael, Andreas Vlachos (47497), Vlachos Andreas, Vlachos, Andreas, Andreas Vlachos, Peter Jedlicka, Jochen Roeper (179944), Becker, Denise, Peter Jedlicka (179938), Raphael Winkels (179941), Deller Thomas, Deller, Thomas, Raphael Winkels   +23 more
core   +1 more source

RIOK3 sustains colorectal cancer cell survival under glucose deprivation via an HSP90α-dependent pathway

Oncogenesis
Glucose oxidation via the pentose phosphate pathway serves as the primary cellular mechanism for generating nicotinamide adenine dinucleotide phosphate (NADPH).
Nan Zhang, Lu Dong, Tingting Ning, Feng Du, Mengran Zhao, Junxuan Xu, Sian Xie, Si Liu, Xiujing Sun, Peng Li, Shutian Zhang, Shengtao Zhu   +11 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Carious Lesion Diagnosis: Methods, Problems, Thresholds.

, 2018
The difference between carious lesion diagnosis and carious lesion detection is discussed here. Concerning carious lesions, 3 diagnostic requirements should be fulfilled: to detect lesions, to assess surface integrity, and to assess lesion activity to ...
Adrian Lussi, Lussi, Adrian, Neuhaus, Klaus W., Klaus W. Neuhaus   +3 more
core   +1 more source

Pathogenicity of the root lesion nematode Pratylenchus neglectus depends on pre-culture conditions [PDF]

, 2023
The ability of a plant parasitic nematode to infect and reproduce within a host plant depends on its genotype and the environmental conditions before and during infection.
Fatemi, Ehsan, Jung, Christian
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Lesion-to-liver contrast-to-noise ratio (CNR) for HCCs.

, 2016
Box-and-whisker plots showing the median (middle line of each box), quartiles (top and bottom lines of each box), and upper and lower adjacent (upper and lower whiskers for each box) values of the lesion-to-liver contrast-to-noise ratio (CNR) for HCCs ...
Eun-Suk Cho (804566), Joo Hee Kim (804567), Jeong-Sik Yu (804568), Dae Jung Kim (629148), Jae-Joon Chung (804569), Inhwan Jeon (3391028)   +5 more
core   +1 more source

Disentangling interoception: insights from focal strokes affecting the perception of external and internal milieus

Frontiers in Psychology, 2015
Interoception is the moment-to-moment sensing of the physiological condition of the body. The multimodal sources of interoception can be classified into two different streams of afferents: an internal pathway of signals arising from core structures (i.e.,
Agustin eIbanez
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Pain relief following spinal lesion treatment with stereotactic radiosurgery: Clinical experience in 65 cases

Journal of Medical Sciences, 2015
Background: This study determines the pain-reducing effect of CyberKnife radiosurgery in the treatment of spinal lesions. Materials and Methods: We evaluated the clinical outcomes of patients treated with CyberKnife radiosurgery for spinal lesions in 65 ...
Shih-Wei Hsu, Hsing-Lung Chao, Kuen-Tze Lin, Yu-Ching Chou, Cheng-Hsiang Lo, Shih-Yu Lee, Wen-Yen Huang, Chun-Shu Lin, Chien-Min Lin, Chao-Yueh Fan, Da-Tong Ju   +10 more
doaj   +1 more source