Results 51 to 60 of about 2,066,107 (321)

Multi-omics Analysis of Gut Microbiota and Metabolites in Rats With Irritable Bowel Syndrome

Frontiers in Cellular and Infection Microbiology, 2019
Irritable bowel syndrome (IBS) is a common gastrointestinal dysfunctional disease. The pathophysiology of IBS is, however, largely unknown. This study aimed to determine whether evaluation of fecal metabolite and microbiota profiles may offer an ...
Si Liu, Chaozeng Si, Yang Yu, Guiping Zhao, Lei Chen, Yu Zhao, Zheng Zhang, Hengcun Li, Yang Chen, Li Min, Shutian Zhang, Shengtao Zhu   +11 more
doaj   +1 more source

Skin Lesions in Children: Evaluation of Clinicopathological Findings

Türk Patoloji Dergisi, 2023
Objective: Pediatric skin diseases may show various manifestations, occasionally affecting the patients quality of life. Histopathological examination may be required for the diagnosis.
Begum CALIM-GURBUZ, Burcin PEHLIVANOGLU, Tuce SOYLEMEZ-AKKURT, Ozan ERDEM, Anvar AHMEDOV   +4 more
doaj   +1 more source

GSplit LBI: Taming the Procedural Bias in Neuroimaging for Disease Prediction

, 2017
In voxel-based neuroimage analysis, lesion features have been the main focus in disease prediction due to their interpretability with respect to the related diseases.
H Zou, J Ashburner, J Ashburner, Jailin Peng, L Grosenick, LI Rudin, LR Dice, R Tibshirani, RJ Tibshirani, Stanley Osher, Z Dai   +10 more
core   +2 more sources

A cutaneous lesion [PDF]

Internal and Emergency Medicine, 2015
A 34-year-old man presented to dermatology clinic with a lesion on his left palm. The lesion was first noticed 2 weeks before presentation as a nodule with gradual enlargement, accompanied by pain. There was no pruritus or bleeding. He was a shepherd with no prior past medical history.
Pouya Entezari, Hadi Mirfazaelian, Ameneh Alaini, Yahya Daneshbod   +3 more
openaire   +3 more sources

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

RIOK3 sustains colorectal cancer cell survival under glucose deprivation via an HSP90α-dependent pathway

Oncogenesis
Glucose oxidation via the pentose phosphate pathway serves as the primary cellular mechanism for generating nicotinamide adenine dinucleotide phosphate (NADPH).
Nan Zhang, Lu Dong, Tingting Ning, Feng Du, Mengran Zhao, Junxuan Xu, Sian Xie, Si Liu, Xiujing Sun, Peng Li, Shutian Zhang, Shengtao Zhu   +11 more
doaj   +1 more source

Study Of The Special Features Of The Meniscal Tear

Central Asian Journal of Medical Sciences, 2023
Objectives: Arthroscopic meniscectomy is a treatment with good short-term results. To prevent the long-term adverse effects of meniscal tear injuries, it is necessary to study the unique features, such asthedemographic characteristics of the injury, the ...
Orgil Zorigtbaatar, Gonchigsuren Dagvasumberel, Naranbat Lkhagvasuren, Baatarjav Sosor   +3 more
doaj   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

FEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura, Lixiang Wang, Nao Hasuzawa, Ayako Nagayama, Sawako Moriyama, Kenji Ashida, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto   +8 more
wiley   +1 more source

From west to east: dissecting the global shift in inflammatory bowel disease burden and projecting future scenarios

BMC Public Health
Background The epidemiology of inflammatory bowel disease (IBD) has changed dramatically worldwide. This survey analyzed patterns and trends in the burden of IBD to aid future decision making.
Kaiqi Yang, Changhao Zhang, Rui Gong, Wei Jiang, Yuchen Ding, Yang Yu, Jinlong Chen, Min Zhu, Jiaxuan Zuo, Xueping Huang, Lumei Wang, Peng Li, Xiujing Sun   +12 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source