Results 101 to 110 of about 92,791 (280)

A Hypothalamic Oxytocinergic–Sympathetic Axis Couples Anxiety Dysregulation With Impaired Tendon–Bone Repair

open access: yesAdvanced Science, EarlyView.
RCI is associated with functional suppression of oxytocinergic neurons in the PVN. Reduced PVNOXT neuronal activity contributes to altered sympathetic regulation involving the IML–sympathetic chain pathway, accompanied by changes in norepinephrine signaling at the BTI.
Liyang Wan   +8 more
wiley   +1 more source

Expresión de BAX y BCL2 en lesiones cervicales

open access: yesV Congreso Internacional de Investigación en Ciencias de la Salud y II Seminario Internacional de Nutrición y Salud Alimentaria, 2021
Jéssica Mestanza   +2 more
openaire   +1 more source

Meningeal Lymphatic LTBR Deficiency Links Spinal Cord Injury to Secondary Brain Pathology

open access: yesAdvanced Science, EarlyView.
Spinal cord injury (SCI) induces remote brain alterations beyond the injured spinal cord. This study links dysfunction of meningeal lymphatic vessels (mLVs) to neuroinflammation and neuronal injury after SCI. LTBR‐mediated lymphatic restoration improves meningeal lymphatic integrity and neurological outcomes, highlighting LTBR as a potential regulator ...
Yi Chen   +12 more
wiley   +1 more source

RBMS1 Contributes to Early Arteriovenous Fistula Neointimal Remodeling Through Modulation of VSMC Phenotypic Responses

open access: yesAdvanced Science, EarlyView.
Postoperative arteriovenous fistulas exhibit increased RBMS1 in vascular smooth muscle cells (VSMCs). In experimental AVFs, RBMS1 overexpression aggravates, whereas deletion attenuates, neointimal hyperplasia. RBMS1 binds MPZL1 mRNA and promotes exon 5 skipping to generate MPZL1‐Δ5, which interacts with G3BP1 to activate AKT, driving VSMC proliferation,
Zongda Li   +14 more
wiley   +1 more source

Photoactivated Platinum Complexes: Targeting Membrane Proteins and Organelles for Precision Cancer Therapy

open access: yesAngewandte Chemie, EarlyView.
This review highlights an emerging anticancer approach integrating platinum agents into photodynamic therapy (PDT) and photoactivated chemotherapy (PACT) systems, further augmented by cancer cell membrane‐ and organelle‐targeting. By directing photoactivated platinum complexes from nontargeted distribution to cancer cells or defined subcellular sites ...
Shu Chen   +3 more
wiley   +2 more sources

Precision Nanomedicine for Traumatic Neural Injury: Functional Paradigms and Translational Frameworks

open access: yesAdvanced Science, EarlyView.
This review presents a pathology‐driven framework unifying nanomedicine across TBI, SCI, and PNI. Epidemiological evidence and comparative single‐cell transcriptomic reanalysis define shared pathological modules, injury‐specific effectors, and therapeutic bottlenecks. Six functional paradigms connect nanomaterial structure and biological fate to injury‐
Mouyuan Sun   +12 more
wiley   +1 more source

Manejo de Heridas Cervicales Penetrantes [PDF]

open access: yes
Las heridas cervicales penetrantes representan una causa importante de morbimortalidad debido al riesgo de hemorragia, compromiso de la vía aérea y lesiones de estructuras vasculares, aerodigestivas y neurológicas.
White, Matthew   +2 more
core  

Astrocytic Ketogenesis Protects Central Nervous System Injury via CPT1A Stabilization and Epigenetic Regulation

open access: yesAdvanced Science, EarlyView.
A distinct astrocyte subpopulation, enriched at the lesion border, drives CNS repair through enhanced ketone body metabolism. This process promotes neuronal survival and axonal sparing via CPT1A stabilization and H3K9bhb‐dependent epigenetic reprogramming, positioning astrocytic ketogenesis as a promising therapeutic target for tissue regeneration ...
Dishui Pan   +14 more
wiley   +1 more source

Estudio histológico de conización con Asa diatérmica en pacientes con lesiones en cérvix

open access: yesArchivo Médico de Camagüey, 2010
Fundamento: la biopsia por conización con Asa diatérmica se aplica con frecuencia en el diagnóstico y tratamiento de la neoplasia intraepitelial cervical.
Bárbara María Martínez Hiriart   +3 more
doaj  

Prevalencia de lesiones cervicales no cariosas en alumnos del I.E.S.T.P. Pedro A. Del Águila Hidalgo – Iquitos – 2025

open access: yes
El presente estudio tuvo por objetivo determinar la prevalencia de Lesiones Cervicales No Cariosas en Alumnos del I.E.S.T.P. Pedro A. del Águila Hidalgo – Iquitos – 2025.
Sangama Navarro, Amidey
core  

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