Results 211 to 220 of about 191,908 (258)

Oral immunization with filovirus-like particles partially protects IFNAR<sup>-</sup>/<sup>-</sup> mice against lethal ebola virus challenge. [PDF]

open access: yesSci Rep
Escudero-Pérez B   +11 more
europepmc   +1 more source

Pharmacokinetics and bio-distribution of differently functionalized Carbon nanotube in Zebrafish, Danio rerio. [PDF]

open access: yesDiscov Nano
Kumari K   +10 more
europepmc   +1 more source

Development of whole virion inactivated Kyasanur Forest Disease vaccine candidate and its preclinical safety and efficacy evaluation. [PDF]

open access: yesFront Immunol
Sunagar R   +12 more
europepmc   +1 more source

A dynamic pharmacometric framework defining the relationship between ivermectin exposure and mosquito lethality

open access: yes
Hoglund RM   +9 more
europepmc   +1 more source
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The lethal heat dose for 50% primary human fibroblast cell death is 48 °C

Archives of Dermatological Research, 2021
Understanding the effect of heat on skin cells is important for the prevention of burn injury. Knowledge of the heat dose required to kill cells can be used to study the cellular mechanisms involved in thermal injury cell death, to assist with the development of novel burn treatments. In this study, primary human skin dermal fibroblasts were exposed to
Elissa Henderson   +8 more
openaire   +5 more sources

Effect of Intraventricular Administration of Antisomatostatin γ-Globulin on the Lethal Dose-50 of Strychnine and Pentobarbital in Rats*

Endocrinology, 1978
Effects of intraventricular injection of sheep anti-somatostatin gamma-globulin (anti-SSG) on strychnine-induced seizures, strychnine LD50, and pentobarbital LD50 were examined in male rats under light ether anesthesia. Ten microliters of anti-SSG given 2 h earlier significantly decreased the duration of strychnine-induced seizures as compared with ...
K, Chihara   +3 more
openaire   +2 more sources

Determination of acute lethal dose 50 (LD50) of uranyl nitrate in male swiss albino mice

Research Journal of Pharmacy and Technology, 2018
Evaluation of LD50 is the foremost step in the assessment of toxicity of a substance. The present study was designed to determine the acute LD50 of uranyl nitrate via intraperitoneal route in male swiss albino mice. The selected single doses of uranyl nitrate from the pilot study conducted were 64, 32, 16, 8, 4mg/kg bdwt.
Sangeetha P. Vijayan   +3 more
openaire   +1 more source

[Ciradian variation in the lethal dose 50 of mercuric chloride in mice].

Comptes rendus des seances de l'Academie des sciences. Serie III, Sciences de la vie, 1982
If circadian variations in tolerance to drugs have been often demonstrated, such observations about heavy metals are still very scarce. The present study proposes to determine if circadian variations occur in the tolerance of Mice to single lethal dose of mercuric chloride. 360 female Mice, kept in cages on a 8.00 - 20.00 L/D cycle, receive I.P.
J, Cambar, J C, Cal
openaire   +1 more source

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