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Oral immunization with filovirus-like particles partially protects IFNAR<sup>-</sup>/<sup>-</sup> mice against lethal ebola virus challenge. [PDF]
Escudero-Pérez B +11 more
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Pharmacokinetics and bio-distribution of differently functionalized Carbon nanotube in Zebrafish, Danio rerio. [PDF]
Kumari K +10 more
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Acute toxicity and sex-dependent lethality of isotonitazene in fischer 344 rats. [PDF]
Hernandez YL, Vinerean H, Aggarwal S.
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Development of whole virion inactivated Kyasanur Forest Disease vaccine candidate and its preclinical safety and efficacy evaluation. [PDF]
Sunagar R +12 more
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The lethal heat dose for 50% primary human fibroblast cell death is 48 °C
Archives of Dermatological Research, 2021Understanding the effect of heat on skin cells is important for the prevention of burn injury. Knowledge of the heat dose required to kill cells can be used to study the cellular mechanisms involved in thermal injury cell death, to assist with the development of novel burn treatments. In this study, primary human skin dermal fibroblasts were exposed to
Elissa Henderson +8 more
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Endocrinology, 1978
Effects of intraventricular injection of sheep anti-somatostatin gamma-globulin (anti-SSG) on strychnine-induced seizures, strychnine LD50, and pentobarbital LD50 were examined in male rats under light ether anesthesia. Ten microliters of anti-SSG given 2 h earlier significantly decreased the duration of strychnine-induced seizures as compared with ...
K, Chihara +3 more
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Effects of intraventricular injection of sheep anti-somatostatin gamma-globulin (anti-SSG) on strychnine-induced seizures, strychnine LD50, and pentobarbital LD50 were examined in male rats under light ether anesthesia. Ten microliters of anti-SSG given 2 h earlier significantly decreased the duration of strychnine-induced seizures as compared with ...
K, Chihara +3 more
openaire +2 more sources
Determination of acute lethal dose 50 (LD50) of uranyl nitrate in male swiss albino mice
Research Journal of Pharmacy and Technology, 2018Evaluation of LD50 is the foremost step in the assessment of toxicity of a substance. The present study was designed to determine the acute LD50 of uranyl nitrate via intraperitoneal route in male swiss albino mice. The selected single doses of uranyl nitrate from the pilot study conducted were 64, 32, 16, 8, 4mg/kg bdwt.
Sangeetha P. Vijayan +3 more
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[Ciradian variation in the lethal dose 50 of mercuric chloride in mice].
Comptes rendus des seances de l'Academie des sciences. Serie III, Sciences de la vie, 1982If circadian variations in tolerance to drugs have been often demonstrated, such observations about heavy metals are still very scarce. The present study proposes to determine if circadian variations occur in the tolerance of Mice to single lethal dose of mercuric chloride. 360 female Mice, kept in cages on a 8.00 - 20.00 L/D cycle, receive I.P.
J, Cambar, J C, Cal
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