Results 271 to 280 of about 731,605 (329)

Proof of concept for high-dose Cannabidiol pretreatment to antagonize opioid induced persistent apnea in mice. [PDF]

Front Neurosci
Wiese BM, Bondarenko E, Feldman JL.
europepmc   +1 more source

Direct Extracellular Matrix Modulation Attenuates Intestinal Fibrosis via a Fibronectin‐Targeted Approach

Advanced Science, EarlyView.
Fibronectin regulates the extracellular matrix (ECM)–myofibroblast cycle through three key steps: (1) its secretion and assembly by myofibroblasts (inhibited by pUR4); (2) collagen deposition along its scaffold (inhibited by R1R2); and (3) integrin α5β1‐mediated mechanotransduction (inhibited by ATN161).
Wenlong Ma, Siyu Yang, Tengkai Wang, Di Zhang, Hewei Wu, Shichen Fu, Xiaohan Wan, Lixiang Li, Xiuli Zuo, Yanqing Li, Jiaoyang Lu   +10 more
wiley   +1 more source

Immune Responses and Protective Efficacy of Nanoemulsion-Adjuvanted Monkeypox Virus Recombinant Vaccines Against Lethal Challenge in Mice. [PDF]

Pathogens
Zhang C, Liu N, Zhao Y, Pan Z, Wang D, Tang W, He Y, Zheng X, Qi Z, Zhang X, Zhao P.   +10 more
europepmc   +1 more source

Pathogenicity of Theileria parva is influenced by the host cell type infected by the parasite [PDF]

, 1996
Lalor, Paul A, MacHugh, Niall, Morrison, Ivan   +2 more
core  

Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma

Advanced Science, EarlyView.
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian, Sreenidhi Mohanvelu, Sheeja Aravindan, Afsana Parveen Jahir Hussain, Sivasubramani Narayanan, Sabir Salim, Loganayaki Periyasamy, Natarajan Aravindan   +7 more
wiley   +1 more source

Pyrethroid Resistance in Anopheles gambiae s.l.: A Focus on Permethrin and Deltamethrin for Malaria Vector Control. [PDF]

Rev Soc Bras Med Trop
Adesoye OA, Awoniyi AM, Adeogun AO.
europepmc   +1 more source

Disrupting Lipid Raft Microdomains to Block Polyploid Giant Cancer Cell Budding and Enhance Radiotherapy Response

Advanced Science, EarlyView.
Radiation induces polyploid giant cancer cells (PGCCs) that regenerate tumors through virus‐like budding. This process depends on a SNCG–FLOT2–CHMP4B signaling axis functioning in lipid raft microdomains. Disrupting these domains using statins or anti‐PCSK9 antibodies blocks PGCC budding, suppresses tumor repopulation, and enhances radiotherapy ...
Zheng Deng, Haoran Sun, Jin Cheng, Ruyi Zhao, Jianzhu Xie, Yanwei Song, Yucui Zhao, Chenwei Lin, Binjie Hu, Yanping Gong, Jun Lin, Sijia He, Yuntao Luo, Minghui Zhao, Yiwei Wang, Ming Jiao, Yuqin Yang, Jikun Li, Shujie Xia, Chuanyuan Li, Qian Huang   +20 more
wiley   +1 more source

A Dual-Targeted Therapy with Fucoidan-Functionalized Thrombolytic Discoidal Microparticles for Pulmonary Thromboembolism. [PDF]

Drug Des Devel Ther
Choi W, Cho H, Jang H, Park H, Youn I, Han S, Key J.   +6 more
europepmc   +1 more source

<i>In Vitro</i> Termiticidal Activity of Medicinal Plant Essential Oils Against <i>Microcerotermes crassus</i>. [PDF]

Insects
Chantarapitak C, Pumnuan J, Chanpitak C, Kramchote S.   +3 more
europepmc   +1 more source

[Determination of the 50% lethal dose (LD50) of endotoxins (F68) from coliform bacteria with and without Salmonella antigen].

Boletin medico del Hospital Infantil de Mexico, 2003
openaire   +1 more source