Strategies to rescue the consequences of inducible arginase-1 deficiency in mice [PDF]
, 2015 Arginase-1 catalyzes the conversion of arginine to ornithine and urea, which is the final step of the urea cycle used to remove excess ammonia from the body.
Ballantyne, Laurel L +9 more
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Risks for public health related to the presence of tetrodotoxin (TTX) and TTX analogues in marine bivalves and gastropods [PDF]
, 2017 Peer reviewedPublisher ...
EFSA Panel on Contaminants in the Food Chain (CONTAM)
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Combined immunosuppressive therapy with low dose FK506 and antimetabolites in rat allogeneic heart transplantation [PDF]
, 1994 Following rat heterotopic heart allotransplantation, low to lethal doses of the antimetabolites mizoribine (MIZ), RS-61443 (RS), and AZA were given alone or in combination with subtherapeutic doses of FK506 (0.04 mg/kg/day) for 14 days after ...
Fujisaki, S +6 more
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Lethal Dose Conjecture on Data Poisoning
Advances in Neural Information Processing Systems 35, 2022 36th Conference on Neural Information Processing Systems (NeurIPS 2022)
Wenxiao Wang 0002 +2 more
openaire +3 more sources
Chemical-free inactivated whole influenza virus vaccine prepared by ultrashort pulsed laser treatment [PDF]
, 2014 There is an urgent need for rapid methods to develop vaccines in response to emerging viral pathogens. Whole inactivated virus (WIV) vaccines represent an ideal strategy for this purpose; however, a universal method for producing safe and immunogenic ...
Achilefu, Samuel +10 more
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Wild bee toxicity data for pesticide risk assessments [PDF]
, 2019 Pollination services are vital for agriculture, food security and biodiversity. Although many insect species provide pollination services, honeybees are thought to be the major provider of this service to agriculture. However, the importance of wild bees
Lewis, Kathleen, Tzilivakis, John
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Consequences of the Lack of IL-10 in Different Endotoxin Effects and its Relationship With Glucocorticoids [PDF]
, 2019 Sepsis constitutes one of the major causes of death in ICUs. In sepsis induced by gram-negative, although lipopolysaccharide (LPS) initially induces an exacerbated secretion of proinflammatory cytokines leading to endotoxic shock and death resembling a ...
Barrientos, Gabriela Laura +10 more
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Calculation of the Median Lethal Dose and Low Lethal Dose Using the CombiStats Biometric Software
The Bulletin of the Scientific Centre for Expert Evaluation of Medicinal Products, 2021 The median lethal dose (LD50) and low lethal dose (LD10) are calculated in acute toxicity studies, as well as during specific activity assessment of some medicines. The aim of the study was to develop a procedure for using CombiStats to calculate LD50 and LD10.
P. V. Shadrin +3 more
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His+ reversions Caused in Salmonella typhimurium by different types of ionizing radiation [PDF]
, 1988 The yield of his+ reversions in the Ames Salmonella tester strain TA2638 has been determined for 60Co γ rays, 140 kV X rays, 5.4 keV characteristic X rays, 2.2 MeV protons, 3.1 MeV α particles, and 18 MeV/U Fe ions.
Fitzek, M. +3 more
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The dose makes the poison: have “field realistic” rates of exposure of bees to neonicotinoid insecticides been overestimated in laboratory studies? [PDF]
, 2014 Recent laboratory based studies have demonstrated adverse sub-lethal effects of neonicotinoid insecticides on honey bees and bumble bees, and these studies have been influential in leading to a European Union moratorium on the use of three neonicotinoids,
BARON G L +16 more
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